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Gene-Related Products
IRS2 Mouse Monoclonal Antibody (clone 8S15)
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| AHO1532 | 100 µg | 299.00 |
Description
Insulin exerts its effects by binding to the insulin receptor, a disulfide-linked heterotetrameric protein composed of two α subunits and two β subunits. The α View full product details >
General Specifications
- Reactivity
-
Mouse
Human
- Validated Application
-
Western Blot
- Host
-
Mouse
- Clonality
-
Monoclonal
- Clone ID
-
8S15
- Target Gene
-
IRS2
- Gene ID
-
8660
- Label or Dye
-
Unconjugated
- Purification
-
Affinity Purified
- Product Size
-
100 µg
- Research Category
-
Signal Transduction
- Shipping Condition
-
Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productAHO1532
0c5abf43ed5452c7cb73ae019fc0ac9e_CmgtBuyProduct
IRS2 Mouse Monoclonal Antibody (clone 8S15)
MSDS
d548811f6f11b350872ffd4c81699a32_MSDS
Neuronal insulin receptor substrate 2 (IRS2) expression is regulated by ZBP89 and SP1 binding to the IRS2 promoter.
Citations & References
- Authors: Udelhoven M, Pasieka M, Leeser U, Krone W, Schubert M
- Journal: J Endocrinol 2010 2:199-208
- Product Usage: StepOne™ Real-Time PCR System
- ID: PN128665
- Catalog #s
- 4376357
- 4376373
- 4376374
- 4379216
- ZGEXSCSTEPONE
- ZGEXSCSTEPONE3Y
72ea57591960a001a06de152ffa71ca4_Citations
Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.
Citations & References
- Authors: Park S, Dong X, Fisher TL, Dunn S, Omer AK, Weir G, White MF
- Journal: J Biol Chem 2006 (281):1159-1168
- Product Usage:
- ID: PN130613
dbf6a87972c70dc9aa91d017d92d22b8_Citations
Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth.
Citations & References
- Authors: Dong X, Park S, Lin X, Copps K, Yi X, White MF
- Journal: J Clin Invest (2006) 116:101-114
- Product Usage:
- ID: PN59140
- Catalog #s
- A22189
cc02d42b8939768b8a4f1e4d826faa79_Citations
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice.
Citations & References
- Authors: Killick R, Scales G, Leroy K, Causevic M, Hooper C, Irvine EE, Choudhury AI, Drinkwater L, Kerr F, Al-Qassab H, Stephenson J, Yilmaz Z, Giese KP, Brion JP, Withers DJ, Lovestone S
- Journal: Biochem Biophys Res Commun 2009 1:257-262
- Product Usage: TaqMan® Gene Expression Assays
- ID: PN124243
792e863023d320156ef8cc8b6a695fa3_Citations
Associations among IRS1, IRS2, IGF1, and IGFBP3 genetic polymorphisms and colorectal cancer.
Citations & References
- Authors: Slattery ML; Samowitz W; Curtin K; Ma KN; Hoffman M; Caan B; Neuhausen S
- Journal: Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association for Cancer Research, Cosponsored By the American Society of Preventive Oncology 2004 7:1206-1214
- Product Usage: AmpliTaq Gold® Reagents
- ID: PN92197
410752bab2cba660c9a996619e104261_Citations
Array Plate: Human IL-9 Pathway (XLS)
Manual / Product Insert
f0ba46d49fb8aaa73c357600ce574db8_Manuals
Array Plate: Human Diabetes (XLS)
Manual / Product Insert
87da00efc5e7f70a6361d0492957b9cc_Manuals
Reference: Reference: cAMP-Screen Direct® Immunoassay System
Product Literature
- Download
- Version: 5 December 2008
eb76c035d5d0a2bd2a0d0834b93c9c26_Brochures
ABfinity™ IL9 Recombinant Rabbit Oligoclonal Antibody
Manual / Product Insert
e6e20a281ef337d524062368acecd1c4_Manuals
ABfinity™ IL-9 Recombinant Rabbit Monoclonal Antibody
Manual / Product Insert
2ec6792786944a49d0f482b57d9b0432_Manuals
Array Plate: Human Interferon Pathway (XLS)
Manual / Product Insert
fd95de778a7546239dbe44d067c96b74_Manuals
Interferon (IFN)
Overview
To find antibodies, assays, and proteins associated with the interferon pathway.
4c0bc9ca06b250de578af2a0433334f7_DayContent
