IRAK4 Monoclonal Antibody (clone 12H2L6), ABfinity™ Recombinant

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
700026 100 µg 299.00

Description

ABfinity™ Recombinant Rabbit Monoclonal Antibody validated to Human and expected reactivity with human, mouse, rat, primates, sheep, equine, swine, bovine, canine, Xenopus.   View full product details >

General Specifications

Reactivity
Human
Validated Application
Flow Cytometry
Immunofluorescence
Host
Rabbit
SubClass (Isotype)
IgG
Clonality
Monoclonal
Clone ID
12H2L6
Antibody Fragment
Whole Antibody
Target Gene
IRAK4
Gene ID
51135
Accession Number
Q9NWZ3
Label or Dye
Unconjugated
Purification
Affinity Purified
Concentration
0.5 mg⁄ml
Color
Unconjugated
Form
Liquid
Neutralizing Antibody
No
Platform
Fluorescence Microscope
Confocal Microscope
Flow Cytometer
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Quantity
1
Volume
200 µl
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis

User Ratings

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700026
2593caa8add446dbd09827b57dd46280_CmgtBuyProduct

IRAK4 Rabbit Polyclonal Antibody View 1 Citations

See all Protein Specific Primary Antibodies

Catalog # Unit Size List Price
365500 100 µg 299.00

Description

For improved reproducibility and sensitivity please try IRAK4 ABfinity™ Recombinant Rabbit Monoclonal Antibody Catalog# 700026.
Rabbit anti-IRAK4, Unconjugated Polyclonal   View full product details >

General Specifications

Reactivity
Human
Validated Application
Immunofluorescence
Western Blot
Host
Rabbit
Clonality
Polyclonal
Target Gene
IRAK4
Gene ID
51135, 266632, 300177
Label or Dye
Unconjugated
Purification
Epitope Affinity Purified
Product Size
100 µg
Protein Family
Kinases & Inhibitors
Research Category
Signal Transduction
Shipping Condition
Wet Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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365500
ed95e3678485d39be74bba14f5b22043_CmgtBuyProduct

IRAK4 Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV3362 10 µg 376.00

Description

IL-1 receptor associated kinases (IRAKs) are serine⁄threonine kinases involved in signaling via Toll⁄IL-1 pathways.   View full product details >

General Specifications

Gene ID
51135
Species
Human
Target Gene
interleukin-1 receptor-associated kinase 4
Gene Aliases
IRAK4
Kinase Group
Ser⁄Thr Kinases: TKL Group
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_057207
Molecular Weight
55.6 kDa
Research Category
Signal Transduction
System Compatibility
Z'-LYTE™
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
IRAK Kinase Family
Protein Form
Recombinant
Full Length
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3362
c7986cecab62fc0b5695ad52aad1ce02_CmgtBuyProduct

IRAK4 Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4002 1 mg 5400.00

Description

IL-1 receptor associated kinases (IRAKs) are serine⁄threonine kinases involved in signaling via Toll⁄IL-1 pathways.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
IRAK4
Kinase Group
Ser⁄Thr Kinases: TKL Group
Product Size
1 mg
Accession Number
NP_057207
Molecular Weight
55.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
IRAK Kinase Family
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4002
591d2a132879eda1198da46625ddc209_CmgtBuyProduct

IRAK4 Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PR5612U 100 µg 1250.00

Description

IL-1 receptor associated kinases (IRAKs) are serine⁄threonine kinases involved in signaling via Toll⁄IL-1 pathways.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
IRAK4
Kinase Group
Ser⁄Thr Kinases: TKL Group
Product Size
100 µg
Accession Number
NP_057207
Molecular Weight
55.6 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
His Tag
Expression
Baculovirus
Kinase Family
IRAK Kinase Family
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

User Ratings

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8624da411ce1a8d45544d110a873df8c_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 7 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3180 800 × 20 µl assays 522.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide contains a PKC consensus sequence (R⁄K)   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
Label or Dye
Coumarin
Product Size
800 × 20 µl assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
NEK2, NEK9, PASK, PHKG1, PHKG2, PIM1, PIM2, PKN1, PKC
ROCK1, RPS6KB1, SRPK2, STK3, STK4, STK24, STK25, TAOK2
CHEK2, IRAK4, MAP3K9, MAP4K2, MAP4K4, MAP4K5, MINK1, MST4, NEK1
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
PKC consensus sequence (R⁄K)1-3(X)0-2 S⁄T (X)0-2(R⁄K)1-3
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis
  • RNAi, Epigenetics & Non-Coding RNA Research

User Ratings

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PV3180
b20b314506c47c1b0d85b1a3b0ebf4d2_CmgtBuyProduct

IRAK4 LanthaScreen Eu Kinase Binding Assay Validation Packet

Manual / Product Insert

Catalog #s
PV3362
e31a1ba03ccbd7a24310cfb120957746_Manuals

Rabbit anti-IRAK4

Manual / Product Insert

Catalog #s
365500
e92d74ccacdc984afa0c517ad0d557a6_Manuals

IRAK4 Rabbit Polyclonal Antibody

MSDS

MSDS Files
365500
Catalog #s
365500
6d4d379eff8f161a9ade5aa60dd376e6_MSDS

IRAK4 Recombinant Human Protein

MSDS

MSDS Files
PV3362
Catalog #s
PV3362
9aca27878c0781792365f03f2cb838e2_MSDS

IRAK4 Recombinant Human Protein

MSDS

MSDS Files
PV4002
Catalog #s
PV4002
61630500025a3a458e914d784d1b1331_MSDS

IRAK4 Monoclonal Antibody (clone 12H2L6), ABfinity™ Recombinant

MSDS

MSDS Files
700026
Catalog #s
700026
1702b4d4b7bf510c45f0201041c9df3b_MSDS

A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity.

Citations & References

  • Authors: Kim TW, Staschke K, Bulek K, Yao J, Peters K, Oh KH, Vandenburg Y, Xiao H, Qian W, Hamilton T, Min B, Sen G, Gilmour R, Li X
  • Journal: J Exp Med 2007 5:1025-1036
  • Product Usage: 7300 Real-Time PCR System
  • ID: PN121369
Catalog #s
111
4330087R
4350814
4351101
4351101R
4351103
4351103R
4359284
4359286
4363914
4363915
4367246
4379633
4379635
ZGEXSC7300
ZGEXSC73003Y
5ab668e1aea1ee3f263cd9012cd72aef_Citations

IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease.

Citations & References

  • Authors: Staschke KA, Dong S, Saha J, Zhao J, Brooks NA, Hepburn DL, Xia J, Gulen MF, Kang Z, Altuntas CZ, Tuohy VK, Gilmour R, Li X, Na S
  • Journal: J Immunol 2009 1:568-577
  • Product Usage: TaqMan® MicroRNA Assays;TaqMan® Gene Expression Assays
  • ID: PN127490
Catalog #s
4331182
4351368
4351370
4351372
3e35b029a125702c450fedec34814493_Citations