IKBKE (IKK Epsilon) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4875 10 µg 376.00

Description

IKBKE is an activator of nuclear factor-kappa-B. Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death.   View full product details >

General Specifications

Gene ID
9641
Species
Human
Target Gene
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
Gene Aliases
IKBKE (IKK Epsilon)
Kinase Group
Ser⁄Thr Kinases: Other
Product Size
10 µg
Protein Family
Kinases & Inhibitors
Protein Subtype
Serine⁄Threonine Kinases
Accession Number
NP_054721
Molecular Weight
107.9 kDa
Research Category
Oncology
Signal Transduction
System Compatibility
Z'-LYTE™
LanthaScreen™ Substrate
LanthaScreen™ Antibody
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
IKK Kinase Family
Protein Form
Full Length
Recombinant
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4875
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IKBKE (IKK Epsilon) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PR8031B 100 µg 1385.00

Description

IKBKE is an activator of nuclear factor-kappa-B. Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
IKBKE (IKK Epsilon)
Kinase Group
Ser⁄Thr Kinases: Other
Product Size
100 µg
Accession Number
NP_054721
Molecular Weight
107.9 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
IKK Kinase Family
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Proteins, Expression, Isolation & Analysis

User Ratings

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IKBKE (IKK Epsilon) Recombinant Human Protein

See all Serine⁄Threonine Kinases

Catalog # Unit Size List Price
PV4876 1 mg 8800.00

Description

IKBKE is an activator of nuclear factor-kappa-B. Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death.   View full product details >

General Specifications

Form
Frozen
Species
Human
Gene Aliases
IKBKE (IKK Epsilon)
Kinase Group
Ser⁄Thr Kinases: Other
Product Size
1 mg
Accession Number
NP_054721
Molecular Weight
107.9 kDa
Research Category
Drug Development
Validated Application
Kinase Assay
Protein Tag or Fusion
GST Tag
Expression
Baculovirus
Kinase Family
IKK Kinase Family
Protein Form
Full Length
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV4876
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LanthaScreen® Tb-IKBa pSer32 Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3562 25 µg 3458.00

Description

An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.

For use in combination   View full product details >

General Specifications

Format
384-well plate
Gene ID
1147, 2869, 3551
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Terbium (Tb)
Product Size
25 µg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
CHUK, GRK5, GRK6, IKBKB, IKBKE
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3562
dad739872c9b70a0eedf2293d056966d_CmgtBuyProduct

Z′-LYTE® Kinase Assay Kit - Ser/Thr 11 Peptide

See all Kinase Assay Kits

Catalog # Unit Size List Price
PV3670 800 × 20 µl assays 522.00

Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon bovine beta-casein A2,   View full product details >

General Specifications

Format
384-well plate
Readout
End Point
Technique
FRET
Assay Type
Serine⁄Threonine Kinase Assay
References
Eur. J. Biochemistry, 186, pp.459-464 (1989)
Label or Dye
Coumarin
Product Size
800 × 20 µl assays
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
CSNK1A1, CSNK1D, CSNK1E, CSNK2A1 , CSNK2A2, IKBKE, FRAP1 (mTOR)
Number of Reactions
800 Reactions
Substrate Properties
Peptide-Based Substrate
Protein or Peptide Source
bovine ß-casein A2 residues 14-21 (ESLSSSEE)
Excitation⁄Emission (nm)
405⁄465, 535
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3670
7d273ef1c88557e78d0276197e30bc67_CmgtBuyProduct

Fluorescein-IKK Substrate

See all Kinase & Phosphatase Substrates

Catalog # Unit Size List Price
PV3507 1 mg 655.00

Description

A fluorescein-labeled peptide substrate that is primarily used with the IkappaB kinase (IKK) family.

For use in combination with the LanthaScreenâ„¢ Tb-IkappaBalpha [   View full product details >

General Specifications

Gene ID
1147, 2869, 3551
Substrate
Fluorescein-IKK
Label or Dye
FITC (Fluorescein)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1864 Da
Validated Kinases
CHUK, GRK5, GRK6, IKBKB, IKBKE
Amino Acid Sequence
Fluorescein- DRHDSGLDSMKDE
Substrate Properties
Peptide-Based Substrate
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

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PV3507
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LanthaScreen® Tb-IKBa pSer32 Antibody Kit

See all TR-FRET Primary Antibodies

Catalog # Unit Size List Price
PV3563 1 mg 17620.00

Description

An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.

For use in combination   View full product details >

General Specifications

Format
384-well plate
Gene ID
1147, 2869, 3551
Readout
End Point
Technique
TR-FRET
Reactivity
Human
Label or Dye
FITC (Fluorescein)
Terbium (Tb)
Product Size
1 mg
Target Enzyme
Serine⁄Threonine Kinases
Validated Kinases
CHUK, GRK5, GRK6, IKBKB, IKBKE
Antibody Molecular Weight
150000 Da
Excitation⁄Emission (nm)
340⁄490, 520
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

Ratings IconRate this product

PV3563
b8e9ac86ff58a32b530e1ba38b1895f9_CmgtBuyProduct

Omnia® S/T Peptide 24 Kit

See all Kinase Assay Kits

Catalog # Unit Size List Price
KNZ1241 1 Kit 901.00

Description

The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to   View full product details >

General Specifications

Form
Frozen
Color
Green
Gene ID
1452, 1453, 1454, 1455, 1456, 53944
Readout
Kinetic
Platform
Microplate Reader
Technique
Fluorescence Intensity
Assay Type
Serine⁄Threonine Kinase Assay
References
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
Label or Dye
Sox Chelation-Enhanced Fluorophore
Product Size
1 Kit
Target Enzyme
Serine/Threonine Kinases
Substrate Type
Kinase Substrate
Detection Method
Fluorescent
Molecular Weight
1939.7 Da
Validated Kinases
CSNK1A1 (CK1), CSNK1D, CSNK1E, CSNK1G1, CSNK1G2, CSNK1G3, IKBKE
Amino Acid Sequence
Ac-KRRRALS(pS)VASLdP(Sox)G-NH2
Substrate Properties
Peptide-Based Substrate
Excitation⁄Emission (nm)
360⁄485
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Drug Discovery & Development
  • Proteins, Expression, Isolation & Analysis

User Ratings

Ratings IconRate this product

KNZ1241
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IKBKE LanthaScreen Eu Binding Assay Validation Packet

Manual / Product Insert

Catalog #s
PV4875
44c9a4254627e41e9842bbf690a37dcc_Manuals

IKBKE LanthaScreen Activity Assay Validation Packet

Manual / Product Insert

Catalog #s
PV4875
b1a6da1fe555b20268bf9ce70ed980e7_Manuals

IKBKE (IKK Epsilon) Recombinant Human Protein

MSDS

MSDS Files
PV4875
Catalog #s
PV4875
b35a6b4d8e7d70998c60a359361ffdb6_MSDS

IKBKE (IKK Epsilon) Recombinant Human Protein

MSDS

MSDS Files
PV4876
Catalog #s
PV4876
34a6bb8278df58896b73d6fa8d4f744d_MSDS

TargetSeq BED hg19 with Gene Names

Manual / Product Insert

Catalog #s
A14060
A14061
A14062
A14063
A14177
A14178
9256f177e09e1f3f6f860a86373b3aad_Manuals

4378701 Plate Info

Manual / Product Insert

Catalog #s
4378701
fc524d9465535e3f32c487236668155f_Manuals