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IKBKE (IKK Epsilon) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4875 | 10 µg | 376.00 |
Description
IKBKE is an activator of nuclear factor-kappa-B. Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death. View full product details >
General Specifications
- Gene ID
-
9641
- Species
-
Human
- Target Gene
-
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
- Gene Aliases
-
IKBKE (IKK Epsilon)
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Serine⁄Threonine Kinases
- Accession Number
-
NP_054721
- Molecular Weight
-
107.9 kDa
- Research Category
-
Oncology
Signal Transduction
- System Compatibility
-
Z'-LYTE™
LanthaScreen™ Substrate
LanthaScreen™ Antibody
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
Recombinant
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
IKBKE (IKK Epsilon) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR8031B | 100 µg | 1385.00 |
Description
IKBKE is an activator of nuclear factor-kappa-B. Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death. View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
IKBKE (IKK Epsilon)
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
100 µg
- Accession Number
-
NP_054721
- Molecular Weight
-
107.9 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
IKBKE (IKK Epsilon) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4876 | 1 mg | 8800.00 |
Description
IKBKE is an activator of nuclear factor-kappa-B. Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death. View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
IKBKE (IKK Epsilon)
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
1 mg
- Accession Number
-
NP_054721
- Molecular Weight
-
107.9 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-IKBa pSer32 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3562 | 25 µg | 3458.00 |
Description
An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.
For use in combination
View full product details >
General Specifications
- Format
-
384-well plate
- Gene ID
-
1147, 2869, 3551
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
25 µg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CHUK, GRK5, GRK6, IKBKB, IKBKE
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Z′-LYTE® Kinase Assay Kit - Ser/Thr 11 Peptide
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3670 | 800 × 20 µl assays | 522.00 |
Description
A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon bovine beta-casein A2, View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
FRET
- Assay Type
-
Serine⁄Threonine Kinase Assay
- References
-
Eur. J. Biochemistry, 186, pp.459-464 (1989)
- Label or Dye
-
Coumarin
- Product Size
-
800 × 20 µl assays
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CSNK1A1, CSNK1D, CSNK1E, CSNK2A1 , CSNK2A2, IKBKE, FRAP1 (mTOR)
- Number of Reactions
-
800 Reactions
- Substrate Properties
-
Peptide-Based Substrate
- Protein or Peptide Source
-
bovine ß-casein A2 residues 14-21 (ESLSSSEE)
- Excitation⁄Emission (nm)
-
405⁄465, 535
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-IKK Substrate
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3507 | 1 mg | 655.00 |
Description
A fluorescein-labeled peptide substrate that is primarily used with the IkappaB kinase (IKK) family.
For use in combination with the LanthaScreenâ„¢ Tb-IkappaBalpha [
View full product details >
General Specifications
- Gene ID
-
1147, 2869, 3551
- Substrate
-
Fluorescein-IKK
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Molecular Weight
-
1864 Da
- Validated Kinases
-
CHUK, GRK5, GRK6, IKBKB, IKBKE
- Amino Acid Sequence
-
Fluorescein- DRHDSGLDSMKDE
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-IKBa pSer32 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3563 | 1 mg | 17620.00 |
Description
An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.
For use in combination
View full product details >
General Specifications
- Format
-
384-well plate
- Gene ID
-
1147, 2869, 3551
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CHUK, GRK5, GRK6, IKBKB, IKBKE
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Omnia® S/T Peptide 24 Kit
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| KNZ1241 | 1 Kit | 901.00 |
Description
The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to View full product details >
General Specifications
- Form
-
Frozen
- Color
-
Green
- Gene ID
-
1452, 1453, 1454, 1455, 1456, 53944
- Readout
-
Kinetic
- Platform
-
Microplate Reader
- Technique
-
Fluorescence Intensity
- Assay Type
-
Serine⁄Threonine Kinase Assay
- References
-
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
- Label or Dye
-
Sox Chelation-Enhanced Fluorophore
- Product Size
-
1 Kit
- Target Enzyme
-
Serine/Threonine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Molecular Weight
-
1939.7 Da
- Validated Kinases
-
CSNK1A1 (CK1), CSNK1D, CSNK1E, CSNK1G1, CSNK1G2, CSNK1G3, IKBKE
- Amino Acid Sequence
-
Ac-KRRRALS(pS)VASLdP(Sox)G-NH2
- Substrate Properties
-
Peptide-Based Substrate
- Excitation⁄Emission (nm)
-
360⁄485
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
IKBKE LanthaScreen Eu Binding Assay Validation Packet
Manual / Product Insert
IKBKE LanthaScreen Activity Assay Validation Packet
Manual / Product Insert
IKBKE (IKK Epsilon) Recombinant Human Protein
MSDS
IKBKE (IKK Epsilon) Recombinant Human Protein
MSDS
TargetSeq BED hg19 with Gene Names
Manual / Product Insert