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IKBKB (IKK Beta) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR7489B | 100 µg | 1250.00 |
Description
Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
IKBKB (IKK Beta)
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
100 µg
- Accession Number
-
NP_001547
- Molecular Weight
-
114 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productIKBKB (IKK Beta) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR7489A | 1 mg | 5400.00 |
Description
Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
IKBKB (IKK Beta)
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
1 mg
- Accession Number
-
NP_001547
- Molecular Weight
-
114 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
IKBKB (IKK Beta) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3836 | 10 µg | 376.00 |
Description
Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the View full product details >
General Specifications
- Gene ID
-
3551, 4088
- Species
-
Human
- Target Gene
-
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
- Gene Aliases
-
IKBKB (IKK Beta)
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Serine⁄Threonine Kinases
- Accession Number
-
NP_001547
- Molecular Weight
-
114 kDa
- Research Category
-
Signal Transduction
- System Compatibility
-
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
Recombinant
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-IKK Substrate
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3507 | 1 mg | 655.00 |
Description
A fluorescein-labeled peptide substrate that is primarily used with the IkappaB kinase (IKK) family.
For use in combination with the LanthaScreen™ Tb-IkappaBalpha [
View full product details >
General Specifications
- Gene ID
-
1147, 2869, 3551
- Substrate
-
Fluorescein-IKK
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Molecular Weight
-
1864 Da
- Validated Kinases
-
CHUK, GRK5, GRK6, IKBKB, IKBKE
- Amino Acid Sequence
-
Fluorescein- DRHDSGLDSMKDE
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-IKBa pSer32 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3563 | 1 mg | 17620.00 |
Description
An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.
For use in combination
View full product details >
General Specifications
- Format
-
384-well plate
- Gene ID
-
1147, 2869, 3551
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CHUK, GRK5, GRK6, IKBKB, IKBKE
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Omnia® S/T Peptide 20 Kit
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| KNZ1201 | 1 Kit | 901.00 |
Description
The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to View full product details >
General Specifications
- Form
-
Frozen
- Color
-
Green
- Readout
-
Kinetic
- Platform
-
Microplate Reader
- Technique
-
Fluorescence Intensity
- Assay Type
-
Serine⁄Threonine Kinase Assay
- References
-
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
- Label or Dye
-
Sox Chelation-Enhanced Fluorophore
- Product Size
-
1 Kit
- Target Enzyme
-
Serine/Threonine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Molecular Weight
-
1728.3 Da
- Validated Kinases
-
IKBKB
- Amino Acid Sequence
-
Ac-DRHDpSGLDSMdP(Sox)G-NH2
- Substrate Properties
-
Peptide-Based Substrate
- Excitation⁄Emission (nm)
-
360⁄485
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-IKBa pSer32 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3562 | 25 µg | 3458.00 |
Description
An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.
For use in combination
View full product details >
General Specifications
- Format
-
384-well plate
- Gene ID
-
1147, 2869, 3551
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
25 µg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CHUK, GRK5, GRK6, IKBKB, IKBKE
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
CellSensor® NFkB-bla ME-180 Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1667 | 1 vial | 9949.00 |
Description
The CellSensor® NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Cytokines
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
Z′-LYTE® Kinase Assay Kit - Ser/Thr 5 Peptide
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3178 | 800 × 20 µl assays | 522.00 |
Description
A coumarin and fluorescein-labeled serine⁄threonine peptide substrate which can be used for kinase screening in an antibody-free format. View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
FRET
- Assay Type
-
Serine⁄Threonine Kinase Assay
- Label or Dye
-
Coumarin
- Product Size
-
800 × 20 µl assays
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CSNK1G1, CSNK1G2, CSNK1G3, IKBKB, TBK1
- Number of Reactions
-
800 Reactions
- Substrate Properties
-
Peptide-Based Substrate
- Excitation⁄Emission (nm)
-
405⁄465, 535
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
IKBKB LanthaScreen Binding Assay Validation Packet
Manual / Product Insert
IKBKB LanthaScreen Activity Assay Validation Packet
Manual / Product Insert
IKBKB (IKK Beta) Recombinant Human Protein
MSDS
IKBKB (IKK Beta) Recombinant Human Protein
MSDS
