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- Product Catalog[9]
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- Support & Troubleshoot[1]
CHUK (IKK α) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4310 | 10 µg | 376.00 |
Description
CHUK (IKK alpha) is a serine⁄threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an View full product details >
General Specifications
- Gene ID
-
114294, 1147
- Species
-
Human
- Target Gene
-
conserved helix-loop-helix ubiquitous kinase
- Gene Aliases
-
CHUK (IKK α)
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Serine⁄Threonine Kinases
- Accession Number
-
NP_001269
- Molecular Weight
-
88.7 kDa
- Research Category
-
Signal Transduction
- System Compatibility
-
Adapta™
LanthaScreen™ Substrate
LanthaScreen™ Antibody
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
His Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Recombinant
Full Length
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productLanthaScreen® Tb-IKBa pSer32 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3563 | 1 mg | 17620.00 |
Description
An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.
For use in combination
View full product details >
General Specifications
- Format
-
384-well plate
- Gene ID
-
1147, 2869, 3551
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CHUK, GRK5, GRK6, IKBKB, IKBKE
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
CellSensor® NFkB-bla ME-180 Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1667 | 1 vial | 9949.00 |
Description
The CellSensor® NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably View full product details >
General Specifications
- System
-
CellSensor™
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Druggable Target
-
Cytokines
Signaling Pathway
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
Adapta™ Universal Kinase Assay Kit
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV5099 | 1 kit | 656.00 |
Description
The Adapta™ Universal Kinase Assay Kit is a homogenous, fluorescence-based immunoassay for the detection of ADP produced by kinases or other ATP dependent enzymes.
For
View full product details >
General Specifications
- Format
-
384-well plate
- Gene ID
-
1022, 1147, 120892, 1612, 3376, 5289, 5290, 5294, 8536
- Readout
-
End Point
- Technique
-
TR-FRET
- Assay Type
-
Universal Kinase Assay
- Label or Dye
-
Europium
Alexa Fluor® 647
- Product Size
-
1 kit
- Target Enzyme
-
Kinases (Multiple)
- Validated Kinases
-
CAMK1, CDK7, CDK9, CHUK, LRRK2, PI4KB, PIK3C2B, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3C2A
- Excitation⁄Emission (nm)
-
340⁄615, 665
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-IKBa pSer32 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3562 | 25 µg | 3458.00 |
Description
An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.
For use in combination
View full product details >
General Specifications
- Format
-
384-well plate
- Gene ID
-
1147, 2869, 3551
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
25 µg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CHUK, GRK5, GRK6, IKBKB, IKBKE
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
CHUK (IKK α) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR7619B | 100 µg | 1250.00 |
Description
CHUK (IKK alpha) is a serine⁄threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
CHUK (IKK α)
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
100 µg
- Accession Number
-
NP_001269
- Molecular Weight
-
88.7 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
His Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
CHUK (IKK α) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4327 | 1 mg | 5400.00 |
Description
CHUK (IKK alpha) is a serine⁄threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
CHUK (IKK α)
- Kinase Group
-
Ser⁄Thr Kinases: Other
- Product Size
-
1 mg
- Accession Number
-
NP_001269
- Molecular Weight
-
88.7 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
His Tag
- Expression
-
Baculovirus
- Kinase Family
-
IKK Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-IKK Substrate
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3507 | 1 mg | 655.00 |
Description
A fluorescein-labeled peptide substrate that is primarily used with the IkappaB kinase (IKK) family.
For use in combination with the LanthaScreen™ Tb-IkappaBalpha [
View full product details >
General Specifications
- Gene ID
-
1147, 2869, 3551
- Substrate
-
Fluorescein-IKK
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Molecular Weight
-
1864 Da
- Validated Kinases
-
CHUK, GRK5, GRK6, IKBKB, IKBKE
- Amino Acid Sequence
-
Fluorescein- DRHDSGLDSMKDE
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
IKK-alpha [pSpS176/180] Polyclonal Antibody, Rabbit
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 44714 | 10 blots | 299.00 |
Description
This rabbit anti-IKK-alpha [pSpS176/180] polyclonal antibody is specific to human IKK-alpha [pSpS176/180] and expected to react with mouse (not tested). IKK-alpha [pSpS176/180] View full product details >
General Specifications
- Reactivity
-
Human
- Validated Application
-
Western Blot
- Host
-
Rabbit
- SubClass (Isotype)
-
IgG
- Clonality
-
Polyclonal
- Target Gene
-
IKKalpha [pSpS176/180]
- Gene ID
-
1147
- Label or Dye
-
Unconjugated
- Target Modification State
-
Phospho
- Product Size
-
10 blots
- Protein Family
-
Kinases & Inhibitors
- Research Category
-
Signal Transduction
- Purity or Quality Grade
-
Azide Free
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
T-Cell Receptor (TCR)
Overview
To find antibodies, assays, and proteins associated with the T-Cell Receptor (TCR) pathway.
Genetic variation in the nuclear factor κB pathway in relation to susceptibility to rheumatoid arthritis
Citations & References
- Authors: Dieguez-Gonzalez, R; Akar, S; Calaza, M; Perez-Pampin, E; Costas, J; Torres, M; Vicario, JL; Velloso, ML; Navarro, F; Narvaez, J; Joven, B; Herrero-Beaumont, G; Gonzalez-Alvaro, I; Fernandez-Gutierrez, B; de la Serna, AR; Carreno, L; Lopez-Longo, J; Caliz
- Journal: ANNALS OF THE RHEUMATIC DISEASES 2009 4:579-583
- Product Usage: TaqMan® SNP Genotyping Assays
- ID: PN99660
