- All Results [97]
- Product Catalog[17]
- Buying Guides[0]
- Support & Troubleshoot[66]
Drug Discovery Assays
Advance your drug discovery pipeline today using our comprehensive portfolio of products and services to investigate the major druggable target classes.
FRAP1 (mTOR) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4753 | 10 µg | 793.00 |
Description
FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are View full product details >
General Specifications
- Species
-
Human
- Target Gene
-
FK506 binding protein 12-rapamycin associated protein 1
- Gene Aliases
-
FRAP1 (mTOR)
- Kinase Group
-
Ser⁄Thr Kinases: Atypical
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Serine⁄Threonine Kinases
- Accession Number
-
NP_004949.1
- Molecular Weight
-
163.9 kDa
- Research Category
-
Oncology
Signal Transduction
- System Compatibility
-
LanthaScreen™ Substrate
LanthaScreen™ Antibody
Z'-LYTE™
- Validated Application
-
Kinase Assay
- Protein Length or Portion (a.a.)
-
aa 1360-2549
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
PIKK Kinase Family
- Protein Form
-
Catalytic
Recombinant
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productFRAP1 (mTOR) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | Contact Us |
|---|---|---|---|
| PV4754 | 1 mg |
Description
FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
FRAP1 (mTOR)
- Kinase Group
-
Ser⁄Thr Kinases: Atypical
- Product Size
-
1 mg
- Accession Number
-
NP_004949.1
- Molecular Weight
-
163.9 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
PIKK Kinase Family
- Protein Form
-
Catalytic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
FRAP1 (mTOR) Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR8683B | 100 µg | 2500.00 |
Description
FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
FRAP1 (mTOR)
- Kinase Group
-
Ser⁄Thr Kinases: Atypical
- Product Size
-
100 µg
- Accession Number
-
NP_004949.1
- Molecular Weight
-
163.9 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
PIKK Kinase Family
- Protein Form
-
Catalytic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
1X FRAP1 (mTOR) Assay Buffer
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4794 | 20 ml | 126.00 |
Description
1X Assay Buffer for use with the LanthaScreen™ FRAP1 (mTOR) assays. View full product details >
General Specifications
- Form
-
Liquid
- Product Size
-
20 ml
- Shipping Condition
-
Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen™ Akt HEK293E Cell Line View 1 Citations
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1615 | 1 vial | 9949.00 |
Description
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context. The PI3K⁄AKT View full product details >
General Specifications
- System
-
LanthaScreen™
- Readout
-
TR-FRET
- Reporter
-
GFP (EmGFP)
- Cell Line
-
293E (HEK)
- Cell State
-
Dividing Cells
- Antagonists
-
LY294002
PI-103
- Gene Symbol
-
AKT1
- Product Size
-
1 vial
- Primary Agonist
-
IGF-1
- Detection Method
-
Fluorescent
- Druggable Target
-
Signaling Pathway
Kinases
- Optimal Response
-
IGF-1 (EC50 = 0.42 µg/ml)
- Alternate Agonists
-
Insulin
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
mTOR/FRAP [pS2448] Rabbit Polyclonal Antibody View 1 Citations
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 441125G | 10 blots | 299.00 |
Description
MTOR [pS2448] PAb; Unconjugated Polyclonal antibody specific to Human, Mouse, H, (Rat) mTOR [pS2448]. This antibody is validated for use in Western Blot, Immunocytochemistry⁄ View full product details >
General Specifications
- Reactivity
-
Human
Mouse
- Validated Application
-
Immunofluorescence
Western Blot
- Host
-
Rabbit
- Clonality
-
Polyclonal
- Target Gene
-
mTOR/FRAP [pS2448]
- Gene ID
-
2475
- Label or Dye
-
Unconjugated
- Target Modification State
-
Phospho
- Purification
-
Purified
- Product Size
-
10 blots
- Protein Family
-
Kinases & Inhibitors
- Research Category
-
Signal Transduction
- Shipping Condition
-
Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Z′-LYTE® Kinase Assay Kit - Ser/Thr 11 Peptide
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3670 | 800 × 20 µl assays | 522.00 |
Description
A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon bovine beta-casein A2, View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
FRET
- Assay Type
-
Serine⁄Threonine Kinase Assay
- References
-
Eur. J. Biochemistry, 186, pp.459-464 (1989)
- Label or Dye
-
Coumarin
- Product Size
-
800 × 20 µl assays
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
CSNK1A1, CSNK1D, CSNK1E, CSNK2A1 , CSNK2A2, IKBKE, FRAP1 (mTOR)
- Number of Reactions
-
800 Reactions
- Substrate Properties
-
Peptide-Based Substrate
- Protein or Peptide Source
-
bovine ß-casein A2 residues 14-21 (ESLSSSEE)
- Excitation⁄Emission (nm)
-
405⁄465, 535
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Kinase Tracer 314, 25 µM
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV6087 | 25 µl | 361.00 |
Description
In the LanthaScreen® Eu Kinase Binding Assay, binding of an Alexa Fluor® conjugate or “tracer" such as Kinase Tracer 314 to a kinase is detected by addition of a View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
Kinetic
- Platform
-
Microplate Reader
- Technique
-
TR-FRET
- Assay Type
-
Kinase Binding Assay
- Label or Dye
-
Alexa Fluor® 647
- Product Size
-
25 µl
- Target Enzyme
-
Kinases (Multiple)
- cGMP Compliance
-
non-cGMP Compliant
- Validated Kinases
-
PIK3CD, PIK3CG, FRAP1 (mTOR)
- Excitation⁄Emission (nm)
-
340⁄615, 665
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
User Ratings
mTOR Oligoclonal Antibody, ABfinity™ Recombinant
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 710408 | 100 µg | 290.00 |
Description
This is a purified rabbit anti-human mTOR antibody that can be used in validated applications such as indirect ELISA, western blot (WB), flow cytometry (FC), and View full product details >
General Specifications
- Reactivity
-
Human
- Validated Application
-
Immunocytochemistry
Western Blot
Flow Cytometry
ELISA
- Host
-
Rabbit
- SubClass (Isotype)
-
IgG
- Clonality
-
Oligoclonal
- Clone ID
-
7HCLC
- Antibody Fragment
-
Whole Antibody
- Target Gene
-
mechanistic target of rapamycin (serine/threonine kinase)
- Gene ID
-
2475
- Gene Symbol
-
MTOR
- Accession Number
-
P42345
- Gene Aliases
-
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
- Label or Dye
-
Unconjugated
- Concentration
-
0.5 mg⁄ml
- Form
-
Liquid
- Product Size
-
100 µg
- Protein Family
-
Kinases & Inhibitors
- Buffer
-
PBS (Phosphate Buffered Saline)
- Research Category
-
Cell Cycle & Proliferation
- Other Additives
-
Sodium Azide Preservative
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Proteins, Expression, Isolation & Analysis
User Ratings
mTOR Monoclonal Antibody (clone 7H13L18), ABfinity™ Recombinant View 1 Citations
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 701483 | 100 µg | 299.00 |
Description
This is a purified rabbit anti-human mTOR monoclonal antibody that can be use in the validated applications of indirect ELISA, Western blot, and immunocytochemistry.
View full product details >
General Specifications
- Reactivity
-
Human
- Validated Application
-
Immunocytochemistry
ELISA
Flow Cytometry
Western Blotting
- Host
-
Rabbit
- SubClass (Isotype)
-
IgG
- Clonality
-
Monoclonal
- Clone ID
-
7H13L18
- Antibody Fragment
-
Whole Antibody
- Target Gene
-
mechanistic target of rapamycin (serine/threonine kinase)
- Gene ID
-
2475
- Gene Symbol
-
MTOR
- Accession Number
-
P42345
- Gene Aliases
-
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
- Label or Dye
-
Unconjugated
- Concentration
-
0.5 mg⁄ml
- Form
-
Liquid
- Product Size
-
100 µg
- Protein Family
-
Kinases
- Buffer
-
PBS (Phosphate Buffered Saline)
- Research Category
-
Signal Transduction
- Other Additives
-
Sodium Azide Preservative
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-p4E-BP1 (pThr46) Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4757 | 25 µg | 3458.00 |
Description
A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1 View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
GFP (EmGFP)
Terbium (Tb)
- Product Size
-
25 µg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
FRAP1 (mTOR)
FRAP1 (mTOR)
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
mTOR Mouse Monoclonal Antibody (clone 215Q18)
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| AHO1232 | 100 µg | 299.00 |
Description
mTOR MAb (215Q18) hu, ms, rt ; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat mTOR. This antibody is validated for use in Western Blot. Anti-mTOR recognizes the View full product details >
General Specifications
- Reactivity
-
Human
Mouse
Rat
- Validated Application
-
Western Blot
- Host
-
Mouse
- Clonality
-
Monoclonal
- Clone ID
-
215Q18
- Target Gene
-
mTOR
- Gene ID
-
2475, 56717, 56718
- Label or Dye
-
Unconjugated
- Purification
-
Affinity Purified
- Product Size
-
100 µg
- Protein Family
-
Kinases & Inhibitors
- Research Category
-
Signal Transduction
- Shipping Condition
-
Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-p4E-BP1 (pThr46) Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4758 | 1 mg | 17620.00 |
Description
A part of the PI3K/AKT Pathway, 4E-BP1 (EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1) is a cytosolic protein that is phosphorylated at Thr46 by mTORC1 View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
GFP (EmGFP)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
FRAP1 (mTOR)
FRAP1 (mTOR)
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
