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FOXO3 [pS207]/FOXO1 [pS212] Polyclonal Antibody, Rabbit View 2 Citations
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 441230G | 10 blots | 299.00 |
Description
This rabbit anti-FOXO3 [pS207]/FOXO1 [pS212] polyclonal antibody is specific to human FOXO3 [pS207]/FOXO1 [pS212] and expected to react with rat and mouse (not tested). FOXO3 [ View full product details >
General Specifications
- Reactivity
-
Mouse
Human
- Validated Application
-
Western Blot
- Host
-
Rabbit
- Clonality
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Polyclonal
- Target Gene
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FOXO3 [pS207]/FOXO1 [pS212]
- Gene ID
-
2309, 56484
- Label or Dye
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Unconjugated
- Target Modification State
-
Phospho
- Product Size
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10 blots
- Shipping Condition
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Approved for shipment on Wet or Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productCellSensor® T-REx™ FOXO3 DBE-bla HeLa Cell Line
See all Pathway Analysis Cell Based Assay Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| K1468 | 1 vial | 9949.00 |
Description
The CellSensor® T-REx™ FOXO3 DBE-bla HeLa cell line was engineered by lentiviral transduction of HeLa cervical cancer cells with a FOXO3 response element driving View full product details >
General Specifications
- System
-
CellSensor™
- Cell Line
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HeLa
- Cell State
-
Dividing Cells
- Product Size
-
1 vial
- Detection Method
-
Fluorescent
- Druggable Target
-
Kinases
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
User Ratings
CellSensor T-REx FOXO3 DBE-bla HeLa Cell-based Assay
Manual / Product Insert
Rabbit (polyclonal) Anti-FOXO3 [pS207]/FOXO1 [pS212]
Manual / Product Insert
CellSensor® T-RExTM FOXO3 DBE-bla HeLa Cell Line Validation Packet
Manual / Product Insert
Rabbit (polyclonal) Anti-FOXO1 [pT24]/FOXO3 [pT32]
Manual / Product Insert
CellSensor® T-REx™ FOXO3 DBE-bla HeLa Cell Line
MSDS
Foxo3-/- mice demonstrate reduced numbers of pre-B and recirculating B cells but normal splenic B cell sub-population distribution.
Citations & References
- Authors: Hinman RM, Nichols WA, Diaz TM, Gallardo TD, Castrillon DH, Satterthwaite AB
- Journal: Int Immunol 2009 7:831-842
- Product Usage: TaqMan® Master Mixes;7300 Real-Time PCR System
- ID: PN122412
Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells.
Citations & References
- Authors: Yalcin S, Zhang X, Luciano JP, Mungamuri SK, Marinkovic D, Vercherat C, Sarkar A, Grisotto M, Taneja R, Ghaffari S,
- Journal: J Biol Chem (2008) 283:25692-25705
- Product Usage: Measurement of intracellular ROS by flow cytometry in murine hematopoietic stem cells.
- ID: PN67101
FOXO3 modulates endothelial gene expression and function by classical and alternative mechanisms.
Citations & References
- Authors: Czymai T, Viemann D, Sticht C, Molema G, Goebeler M, Schmidt M
- Journal: J Biol Chem 2010 14:10163-10178
- Product Usage: TaqMan® Gene Expression Assays
- ID: PN127864
Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor.
Citations & References
- Authors: Segura MF, Hanniford D, Menendez S, Reavie L, Zou X, Alvarez-Diaz S, Zakrzewski J, Blochin E, Rose A, Bogunovic D, Polsky D, Wei J, Lee P, Belitskaya-Levy I, Bhardwaj N, Osman I, Hernando E
- Journal: Proc Natl Acad Sci U S A 2009 6:1814-1819
- Product Usage: TaqMan® MicroRNA Assays
- ID: PN122609
Oxidative stress modulates complement factor H expression in retinal pigmented epithelial cells by acetylation of FOXO3.
Citations & References
- Authors: Wu Z, Lauer TW, Sick A, Hackett SF, Campochiaro PA,
- Journal: J Biol Chem (2007) 282:22414-22425
- Product Usage: Human retinal pigment epithelium cell line ARPE-19 was transfected with constructs of FOXO3 (Forkhead Box Protein O3) using lipofectamine LTX. The paper studies the role of acetylation of FOXO3 in oxidative stress modulation of CFH (Complement Factor H). Reduced activity of CFH increases the risk of AMD (age-related macular degeneration), the leading cause of severe vision loss in the elderly.
- ID: PN66361
