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Taqman® Mutation Detection Assays
The TaqMan® Mutation Detection Assays, powered by the castPCR™ technology, provide a highly specific and sensitive method to detect mutations in gene that are associated with cancer.
FGFR3 Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3145 | 10 µg | 376.00 |
Description
FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, View full product details >
General Specifications
- Gene ID
-
2261
- Species
-
Human
- Target Gene
-
fibroblast growth factor receptor 3
- Gene Aliases
-
FGFR3, CEK2, JTK4
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Receptor Tyrosine Kinases
- Accession Number
-
NP_000133
- Molecular Weight
-
49.8 kDa
- Research Category
-
Oncology
Signal Transduction
- System Compatibility
-
LanthaScreen™ Substrate
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Antibody
- Protein Tag or Fusion
-
His Tag
- Validated Application
-
Kinase Assay
- Protein Length or Portion (a.a.)
-
aa 399-806
- Expression
-
Baculovirus
- Kinase Family
-
FGF Receptors
- Protein Form
-
Recombinant
Cytoplasmic
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productFGFR3 [K650E] Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4392 | 10 µg | 376.00 |
Description
FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, View full product details >
General Specifications
- Mass
-
10 µg
- Species
-
Human
- Target Gene
-
fibroblast growth factor receptor 3
- Gene Aliases
-
FGFR3 K650E
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
10 µg
- Tag Position
-
N-Terminal
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Receptor Tyrosine Kinases
- Accession Number
-
NP_000133; K650E
- Molecular Weight
-
49.8 kDa
- Research Category
-
Oncology
Signal Transduction
- System Compatibility
-
LanthaScreen™ Substrate
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Antibody
- Protein Tag or Fusion
-
His Tag
- Validated Application
-
Kinase Assay
- Protein Length or Portion (a.a.)
-
aa 398-806; K650E
- Expression
-
Baculovirus
- Kinase Family
-
FGF Receptors
- Protein Form
-
Recombinant
Cytoplasmic
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
FGFR3 Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4107 | 1 mg | 5400.00 |
Description
FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
FGFR3, CEK2, JTK4
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
1 mg
- Accession Number
-
NP_000133
- Molecular Weight
-
49.8 kDa
- Research Category
-
Drug Development
- Protein Tag or Fusion
-
His Tag
- Validated Application
-
Kinase Assay
- Expression
-
Baculovirus
- Kinase Family
-
FGF Receptors
- Protein Form
-
Cytoplasmic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
FGFR3 [K650E] Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR8155A | 100 µg | 1995.00 |
Description
FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
FGFR3 K650E
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
100 µg
- Accession Number
-
NP_000133; K650E
- Molecular Weight
-
49.8 kDa
- Research Category
-
Drug Development
- Protein Tag or Fusion
-
His Tag
- Validated Application
-
Kinase Assay
- Expression
-
Baculovirus
- Kinase Family
-
FGF Receptors
- Protein Form
-
Cytoplasmic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
FGFR3 Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR4631B | 100 µg | 1250.00 |
Description
FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
FGFR3, CEK2, JTK4
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
100 µg
- Accession Number
-
NP_000133
- Molecular Weight
-
49.8 kDa
- Research Category
-
Drug Development
- Protein Tag or Fusion
-
His Tag
- Validated Application
-
Kinase Assay
- Expression
-
Baculovirus
- Kinase Family
-
FGF Receptors
- Protein Form
-
Cytoplasmic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
FGFR3 [K650E] Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4428 | 1 mg | 9450.00 |
Description
FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
FGFR3 K650E
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
1 mg
- Accession Number
-
NP_000133; K650E
- Molecular Weight
-
49.8 kDa
- Research Category
-
Drug Development
- Protein Tag or Fusion
-
His Tag
- Validated Application
-
Kinase Assay
- Expression
-
Baculovirus
- Kinase Family
-
FGF Receptors
- Protein Form
-
Cytoplasmic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-Poly GT
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3610 | 1 ml | 661.00 |
Description
A general fluorescein peptide substrate consisting of a polymer of glutamate, and tyrosine that is used to monitor tyrosine kinase activity.
For use in combination with the
View full product details >
General Specifications
- Substrate
-
Fluorescein-Poly GT
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 ml
- Target Enzyme
-
Tyrosine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Amino Acid Sequence
-
Fluorescein- Poly Glu:Tyr (4:1)
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-PY20 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3552 | 25 µg | 883.00 |
Description
A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.
For use in
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
25 µg
- Target Enzyme
-
Tyrosine Kinases
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Z′-LYTE® Kinase Assay Kit - Tyrosine 4 Peptide
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3193 | 800 × 20 µl assays | 522.00 |
Description
A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide contains an X-(E⁄D)-Y-(I⁄L⁄ View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
FRET
- Assay Type
-
Tyrosine Kinase Assay
- Label or Dye
-
Coumarin
- Product Size
-
800 × 20 µl assays
- Target Enzyme
-
Tyrosine Kinases
- Validated Kinases
-
EGFR, EPHA2, FGFR, FLT1, FLT4, INSRR, JAK3, MUSK, PDGFRA, PDGFRB
- Number of Reactions
-
800 Reactions
- Substrate Properties
-
Peptide-Based Substrate
- Excitation⁄Emission (nm)
-
405⁄465, 535
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-Poly GAT
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3611 | 1 ml | 661.00 |
Description
A general fluorescein peptide substrate consisting of a polymer of glutamate, alanine, and tyrosine that is used to monitor tyrosine kinase activity.
For use in combination
View full product details >
General Specifications
- Substrate
-
Fluorescein-Poly GAT
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 ml
- Target Enzyme
-
Tyrosine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Amino Acid Sequence
-
Fluorescein- Poly Glu:Ala:Tyr (6:3:1)
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-PY20 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3553 | 1 mg | 7940.00 |
Description
A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.
For use in
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Tyrosine Kinases
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Omnia® Y Peptide 11 Kit
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| KNZ3111 | 1 Kit | 901.00 |
Description
The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to View full product details >
General Specifications
- Form
-
Frozen
- Color
-
Green
- Gene ID
-
1956, 2261, 2263, 2264, 3643, 3717, 3840, 3851, 4233, 4914, 5979, 6098
- Readout
-
Kinetic
- Platform
-
Microplate Reader
- Technique
-
Fluorescence Intensity
- Assay Type
-
Tyrosine Kinase Assay
- References
-
Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)
- Label or Dye
-
Sox Chelation-Enhanced Fluorophore
- Product Size
-
1 Kit
- Target Enzyme
-
Tyrosine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Molecular Weight
-
1875.8 Da
- Validated Kinases
-
AXL, FGFR2, FGFR3, JAK2
- Amino Acid Sequence
-
Ac-KKKKEEIYFFdP(Sox)G-NH2
- Substrate Properties
-
Peptide-Based Substrate
- Excitation⁄Emission (nm)
-
360⁄485
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
