Caspase-8 Colorimetric-Kit

See all Apoptosis Kits

Catalog # Unit Size List Price
KHZ0052 200 tests 598.00

Description

The Caspase-8 fluorometric protease assay kit is designed to measure the activity of Caspase-8. The kit includes substrate and optimized buffers. The substrate, IETD-AFC, is   View full product details >

General Specifications

Format
Cuvettes
96-well plate
Platform
Spectrophotometer
Microplate Reader
Label or Dye
7-amino-4-trifluoromethylcoumarin
Product Size
200 tests
Detection Method
Colorimetric
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis

User Ratings

Ratings IconRate this product

KHZ0052
273e8793aa59b78693ffaa6e9cc4b5a7_CmgtBuyProduct

Caspase-8 Colorimetric-Kit

See all Apoptosis Kits

Catalog # Unit Size List Price
KHZ0061 25 tests 206.00

Description

The Caspase-8 colorimetric protease assay kit provides a simple, convenient means for assaying the activity of Caspase-8 and caspases that recognize the amino acid sequence IETD (   View full product details >

General Specifications

Format
Cuvettes
96-well plate
Platform
Spectrophotometer
Microplate Reader
Label or Dye
pNA
Product Size
25 tests
Detection Method
Colorimetric
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis

User Ratings

Ratings IconRate this product

KHZ0061
2c7022072735af3cc4a1cb36c53b3b42_CmgtBuyProduct

Caspase-8 Colorimetric-Kit

See all Apoptosis Kits

Catalog # Unit Size List Price
KHZ0062 200 tests 598.00

Description

The Caspase-8 colorimetric protease assay kit provides a simple, convenient means for assaying the activity of Caspase-8 and caspases that recognize the amino acid sequence IETD (   View full product details >

General Specifications

Format
Cuvettes
96-well plate
Platform
Spectrophotometer
Microplate Reader
Label or Dye
pNA
Product Size
200 tests
Detection Method
Colorimetric
Shipping Condition
Dry Ice
Regulatory Statement
For Research Use Only. Not for use in diagnostic procedures.

Product Applications

  • Cell Analysis
  • Proteins, Expression, Isolation & Analysis

User Ratings

Ratings IconRate this product

KHZ0062
16d1fdaf0a16a7b970d1736b9edd5eb9_CmgtBuyProduct

Mouse anti-FADD

Manual / Product Insert

Catalog #s
358000
5e6bd7a6970cd4325e587f02667f7f73_Manuals

Increased death receptor pathway of apoptotic signaling in septic mouse aorta: effect of systemic delivery of FADD siRNA

Citations & References

  • Authors: Matsuda, N; Teramae, H; Yamamoto, S; Takano, K; Takano, Y; Hattori, Y
  • Journal: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 2010 1:H92-H101
  • Product Usage: Silencer® siRNAs
  • ID: PN113747
Catalog #s
d08770c01adfc5ec3d3a032c55a93b03_Citations

Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

Citations & References

  • Authors: Micheau O; Solary E; Hammann A; Dimanche-Boitrel M T;
  • Journal: J Biol Chem (1999) 274:7987-8079
  • Product Usage: Transient transfection of HCT116 and HT-29 cells with plasmid DNA by Lipofectamine.
  • ID: PN64823
Catalog #s
11514015
18324111
2591c97a451d43a3f51f510388f02afc_Citations

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD- dependent apoptosis and activate the NF-kappaB pathway.

Citations & References

  • Authors: Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L
  • Journal: Immunity (1997) 7:821-830
  • Product Usage: Death Receptor 5 (DR5) was isolated and its cDNA was cloned into TA cloning vector for sequencing. DR5, its homolog DR4, and other truncated forms were cloned into pSecTag vector for expression in MCF7, a human breast carcinoma cell line; 293T, a subclone of human embryonic kidney cells; and BHK, a baby hamster kidney cell line. DR5 was found to induce apoptosis and activate NF-kappaB using a TRADD-dependent pathway. (Note: Current version of pSecTag is pSecTag2 or pSecTag2/Hygro).
  • ID: PN64345
Catalog #s
K204001
V90020
V91020
582acb16fad542bca597ccb805629749_Citations

The time course of unconditioned morphine-induced psychomotor sensitization mirrors the phosphorylation of FADD and MEK/ERK in rat striatum: role of PEA-15 as a FADD-ERK binding partner in striatal plasticity.

Citations & References

  • Authors: Ramos-Miguel A, Esteban S, García-Sevilla JA,
  • Journal: Eur Neuropsychopharmacol (2010) 20:49-64
  • Product Usage: Western blotting of rat brain extracts
  • ID: PN132633
Catalog #s
44836G
cb7a0065dc72430e2f3c977a34d27f9b_Citations

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB.

Citations & References

  • Authors: Schneider P, Thome M, Burns K, Bodmer JL, Hofmann K, Kataoka T, Holler N, Tschopp J
  • Journal: Immunity (1997) 7:831-836
  • Product Usage: Some members of the tumor necrosis factor (TNF) receptor family efficiently transmit death signals via a cytoplasmic motif called the death domain. TRIAL induces apoptosis through two closely related receptors, TRIAL-R1 (DR4) and TRIAL-R2 (DR5). They are the most receitly identified death receptors. Both TRAIL receptors bind the adaptor molecules FADD and TRADD and both death signals are interrupted by a dominatnt negative form of FADD and by the FLICE-inhibitory protein FLIP. TRIAL receptor
  • ID: PN63993
Catalog #s
V87020
V87520
9037c8d6516fc5f9a5e1e7fd30459de2_Citations

A FADD-dependent innate immune mechanism in mammalian cells.

Citations & References

  • Authors: Balachandran S; Thomas E; Barber GN
  • Journal: Nature 2004 16-Mar:401-405
  • Product Usage: TaqMan® Gene Expression Assays
  • ID: PN70395
Catalog #s
4331182
4351368
4351370
4351372
2e60e2d601506bf037017f71873fb0fc_Citations

SNP genome scanning localizes oto-dental syndrome to chromosome 11q13 and microdeletions at this locus implicate FGF3 in dental and inner-ear disease and FADD in ocular coloboma.

Citations & References

  • Authors: Gregory-Evans CY; Moosajee M; Hodges MD; Mackay DS; Game L; Vargesson N; Bloch-Zupan A; Ruschendorf F; Santos-Pinto L; Wackens G; Gregory-Evans K
  • Journal: Human Molecular Genetics 2008 20:2482-2493
  • Product Usage: Capillary Electrophoresis Systems
  • ID: PN72316
Catalog #s
726734dc97f5a2b993061e2232fe0004_Citations

Aedes FADD: A novel death domain-containing protein required for antibacterial immunity in the yellow fever mosquito, Aedes aegypti

Citations & References

  • Authors: Cooper, DM; Chamberlain, CM; Lowenberger, C
  • Journal: Insect Biochemistry and Molecular Biology 2009 1:47-54
  • Product Usage: Capillary Electrophoresis Systems
  • ID: PN100330
Catalog #s
48f2efc6a6726b4d1d36a4f65ebd9be2_Citations

TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8.

Citations & References

  • Authors: Ikner A, Ashkenazi A,
  • Journal: J Biol Chem (2011) 286:21546-21554
  • Product Usage: Apoptosis Mitochondria MitopProbe Flow
  • ID: PN132264
Catalog #s
M34151
e56989669ba384851370e47c5e295e6f_Citations

Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression.

Citations & References

  • Authors: Lüschen S, Ussat S, Scherer G, Kabelitz D, Adam-Klages S
  • Journal: J Biol Chem (2000) 275:24670-24678
  • Product Usage:
  • ID: PN38168
Catalog #s
D1306
D21490
D23806
D3571
D632
a3d2924150c8fc0c437925e9bc080941_Citations