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DDR2 Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4188 | 1 mg | 5400.00 |
Description
DDR2 is a member of a subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. DDR1 and DDR2 have been shown to be potently inhibited View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
DDR2, TK, NTRKR3
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
1 mg
- Accession Number
-
NP_006173, S642A
- Molecular Weight
-
79.8 kDa
- Research Category
-
Drug Development
- Protein Tag or Fusion
-
GST Tag
- Validated Application
-
Kinase Assay
- Expression
-
Baculovirus
- Kinase Family
-
DDR Kinase Family
- Protein Form
-
Cytoplasmic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productDDR2 Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR7167A | 100 µg | 1250.00 |
Description
DDR2 is a member of a subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. DDR1 and DDR2 have been shown to be potently inhibited View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
DDR2, TK, NTRKR3
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
100 µg
- Accession Number
-
NP_006173, S642A
- Molecular Weight
-
79.8 kDa
- Research Category
-
Drug Development
- Protein Tag or Fusion
-
GST Tag
- Validated Application
-
Kinase Assay
- Expression
-
Baculovirus
- Kinase Family
-
DDR Kinase Family
- Protein Form
-
Cytoplasmic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
DDR2 Recombinant Human Protein
See all Receptor Tyrosine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3870 | 10 µg | 376.00 |
Description
DDR2 is a member of a subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. DDR1 and DDR2 have been shown to be potently inhibited View full product details >
General Specifications
- Gene ID
-
114294, 4921
- Species
-
Human
- Target Gene
-
discoidin domain receptor tyrosine kinase 2
- Gene Aliases
-
DDR2, TK, NTRKR3
- Kinase Group
-
Tyrosine Kinases
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Receptor Tyrosine Kinases
- Accession Number
-
NP_006173, S642A
- Molecular Weight
-
79.8 kDa
- Research Category
-
Signal Transduction
- System Compatibility
-
LanthaScreen™ Antibody
LanthaScreen™ Substrate
- Protein Tag or Fusion
-
GST Tag
- Validated Application
-
Kinase Assay
- Protein Length or Portion (a.a.)
-
aa 427-855
- Expression
-
Baculovirus
- Kinase Family
-
DDR Kinase Family
- Protein Form
-
Recombinant
Cytoplasmic
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-Poly GAT
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3611 | 1 ml | 661.00 |
Description
A general fluorescein peptide substrate consisting of a polymer of glutamate, alanine, and tyrosine that is used to monitor tyrosine kinase activity.
For use in combination
View full product details >
General Specifications
- Substrate
-
Fluorescein-Poly GAT
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 ml
- Target Enzyme
-
Tyrosine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Amino Acid Sequence
-
Fluorescein- Poly Glu:Ala:Tyr (6:3:1)
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Fluorescein-Poly GT
See all Kinase & Phosphatase Substrates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3610 | 1 ml | 661.00 |
Description
A general fluorescein peptide substrate consisting of a polymer of glutamate, and tyrosine that is used to monitor tyrosine kinase activity.
For use in combination with the
View full product details >
General Specifications
- Substrate
-
Fluorescein-Poly GT
- Label or Dye
-
FITC (Fluorescein)
- Product Size
-
1 ml
- Target Enzyme
-
Tyrosine Kinases
- Substrate Type
-
Kinase Substrate
- Detection Method
-
Fluorescent
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Amino Acid Sequence
-
Fluorescein- Poly Glu:Tyr (4:1)
- Substrate Properties
-
Peptide-Based Substrate
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-PY20 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3553 | 1 mg | 7940.00 |
Description
A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.
For use in
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
1 mg
- Target Enzyme
-
Tyrosine Kinases
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-PY20 Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3552 | 25 µg | 883.00 |
Description
A general reagent to monitor tyrosine kinase activity, the pY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate.
For use in
View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
TR-FRET
- Label or Dye
-
FITC (Fluorescein)
Terbium (Tb)
- Product Size
-
25 µg
- Target Enzyme
-
Tyrosine Kinases
- Validated Kinases
-
ABL1, ABL2, AXL, BLK, BMX, BTK, CSF1R, CSK, DDR2, EGFR, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPHB4, ERBB2, ERBB4, FER, FGFR1, FGFR2, FGFR3, FGFR4, FGR, FLT1, FLT3, FLT4, FRK, FYN, HCK, IGF1R, INSR, KDR, KIT, LCK, LTK, LYNA, LYNB, MATK, MERTK, MET, MST1R, MUSK, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PTK2, PTK2B, PTK6, RET, ROS1, SRC, SRCN1, SRMS, SYK, TEC, TEK, TNK2, TTK, TYRO3, YES1, ZAP70
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
DDR2 LanthaScreen Binding Assay Validation Packet
Manual / Product Insert
DDR2 LanthaScreen Activity Assay Validation Packet
Manual / Product Insert
DDR2 Recombinant Human Protein
MSDS
Mutations in DDR2 Gene Cause SMED with Short Limbs and Abnormal Calcifications
Citations & References
- Authors: Bargal, R; Cormier-Daire, V; Ben-Neriah, Z; Le Merrer, M; Sosna, J; Melki, J; Zangen, DH; Smithson, SF; Borochowitz, Z; Belostotsky, R; Raas-Rothschild, A
- Journal: AMERICAN JOURNAL OF HUMAN GENETICS 2009 1:80-84
- Product Usage: Capillary Electrophoresis Systems
- ID: PN98891
TargetSeq BED hg19 with Gene Names
Manual / Product Insert
Binding Assay Kinase Selectivity Data
Product Literature
- Download
- Version: 9 June 2010
