You searched for: CDKN1A [174 matches]

Description

This purified ABfinity™ recombinant rabbit monoclonal antibodyrecognizes human p21 protein.

Specific for p21
The protein p21 is a tumor suppressor protein   View full product details >

General Specifications

Reactivity

Human

Validated Application

Western Blot
ELISA

Host

Rabbit

SubClass (Isotype)

IgG

Clonality

Monoclonal

Clone ID

2H2L13

Antibody Fragment

Whole Antibody

Target Gene

p21

Gene ID

1026

Gene Symbol

CDKN1A

Accession Number

P38936

Label or Dye

Unconjugated

Purification

Purified

Concentration

0.5 mg⁄ml

Form

Liquid

Mass

100 µg

Neutralizing Antibody

No

Product Size

100 µg

Protein Family

Kinases & Inhibitors

Volume

200 µl

Research Category

Cell Cycle & Proliferation

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

p21WAF1 (HJ21) MS X; Unconjugated Monoclonal antibody specific to Human, Mouse, Rat p21WAF1. This antibody is validated for use in Western Blot, Immunohistochemistry,   View full product details >

General Specifications

Reactivity

Rat
Human
Mouse

Validated Application

Western Blot
Immunohistochemistry
Immunofluorescence

Host

Mouse

Clonality

Monoclonal

Clone ID

HJ21

Target Gene

p21WAF1

Gene ID

1026

Label or Dye

Unconjugated

Purification

Purified

Product Size

100 µg

Protein Family

Kinases & Inhibitors

Research Category

Cell Cycle & Proliferation

Shipping Condition

Approved for shipment on Wet or Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine⁄threonine p21-activating   View full product details >

General Specifications

Form

Frozen

Species

Human

Gene Aliases

PAK3, bPAK, hPAK3

Kinase Group

Ser⁄Thr Kinases: STE Group

Product Size

1 mg

Accession Number

NP_002569

Molecular Weight

68.6 kDa

Research Category

Drug Development

Validated Application

Kinase Assay

Protein Tag or Fusion

His Tag

Expression

Baculovirus

Kinase Family

STE20 Kinase Family

Protein Form

Full Length

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

The TaqMan® Array Rat Hepatocarcinogenicity Card contains 23 assays to predict and assess hepatocarcinogenicity of non-genotoxic compounds in rat. The gene signatures were   View full product details >

General Specifications

Form

Dried Down

Format

384-well microfluidic card

Species

Rat

Platform

ViiA™ 7 System

Label or Dye

FAM

Product Size

4 cards

Reaction Speed

Standard

Research Category

Toxicology & Drug Metabolism
Oncology

Product Applications

• Clinical
• Gene Expression Analysis & Genotyping
• PCR & Real-Time PCR

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Description

Mouse anti-p21; Unconjugated Monoclonal antibody specific to Human p21WAF1. This antibody is validated for use in Western Blot, Immunohistochemistry, Immunoassay (ELISA),   View full product details >

General Specifications

Reactivity

Human

Validated Application

Immunofluorescence
Immunohistochemistry
ELISA
Immunoprecipitation
Western Blot

Host

Mouse

Clonality

Monoclonal

Clone ID

EA10

Target Gene

p21

Gene ID

1026

Label or Dye

Unconjugated

Purification

Affinity Purified

Product Size

50 µg

Protein Family

Kinases & Inhibitors

Research Category

Cell Cycle & Proliferation

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

This purified oligoclonal recombinant rabbit IgG antibody recognizes p21 in human samples.

Antibody Specifications:

• Applications: Western blot,

General Specifications

Reactivity

Human

Validated Application

Immunocytochemistry
Western Blot
ELISA

Host

Rabbit

SubClass (Isotype)

IgG

Clonality

Polyclonal

Clone ID

2HCLC

Antibody Fragment

Whole Antibody

Gene ID

1026

Gene Symbol

CDKN1A

Accession Number

P38936

Label or Dye

Unconjugated

Purification

Purified

Concentration

0.5 mg⁄ml

Form

Liquid

Mass

100 µg

Neutralizing Antibody

No

Product Size

100 µg

Protein Family

Kinases & Inhibitors

Volume

200 µl

Comments

Oligoclonal (Pool of Monoclonal Abs to Several Epitopes)

Research Category

Cell Cycle & Proliferation

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon a synthetic peptide substrate   View full product details >

General Specifications

Format

384-well plate

Readout

End Point

Technique

FRET

Assay Type

Serine⁄Threonine Kinase Assay

References

EMBO J. vol. 17, pp. 5913-22 (1998)

Label or Dye

Coumarin

Product Size

800 × 20 µl assays

Target Enzyme

Serine⁄Threonine Kinases

Validated Kinases

PAK2, PAK3, PAK4, PAK6, PAK7, RPS6KA6

Number of Reactions

800 Reactions

Substrate Properties

Peptide-Based Substrate

Protein or Peptide Source

synthetic peptide substrate for NDR1 (KKRNRRLSVA)

Excitation⁄Emission (nm)

405⁄465, 535

Shipping Condition

Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Drug Discovery & Development
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine⁄threonine p21-activating   View full product details >

General Specifications

Form

Frozen

Species

Human

Gene Aliases

PAK3, bPAK, hPAK3

Kinase Group

Ser⁄Thr Kinases: STE Group

Product Size

100 µg

Accession Number

NP_002569

Molecular Weight

68.6 kDa

Research Category

Drug Development

Validated Application

Kinase Assay

Protein Tag or Fusion

His Tag

Expression

Baculovirus

Kinase Family

STE20 Kinase Family

Protein Form

Full Length

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Proteins, Expression, Isolation & Analysis

User Ratings

Rate this product

Description

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine⁄threonine p21-activating   View full product details >

General Specifications

Gene ID

114294, 5063

Species

Human

Target Gene

p21 protein (Cdc42⁄Rac)-activated kinase 3

Gene Aliases

PAK3, bPAK, hPAK3

Kinase Group

Ser⁄Thr Kinases: STE Group

Product Size

10 µg

Protein Family

Kinases & Inhibitors

Protein Subtype

Serine⁄Threonine Kinases

Accession Number

NP_002569

Molecular Weight

68.6 kDa

Research Category

Signal Transduction

System Compatibility

Z'-LYTE™
Omnia® Bulk Substrate

Validated Application

Kinase Assay

Protein Tag or Fusion

His Tag

Expression

Baculovirus

Kinase Family

STE20 Kinase Family

Protein Form

Full Length
Recombinant

Shipping Condition

Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Drug Discovery & Development
• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

The p21 (Total) ELISA kit is designed to detect and quantify the level of p21 protein. This assay is intended for the detection of p21 from human cell lysates using 96-well plates   View full product details >

General Specifications

Marker

p21

Gene ID

1026

Species

Human

Platform

Microplate Reader

Gene Symbol

CDKN1A

Sensitivity

<5 pg⁄ml

Target Gene

p21

Gene Aliases

CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1

Label or Dye

HRP (Horseradish Peroxidase)

Product Size

96 tests

Concentration

15.7-1000 pg⁄ml

Sample Volume

10 µl

Incubation Time

4 hrs

Protein Subtype

Kinase Inhibitors

Detection Method

Colorimetric

Research Category

Cell Cycle & Proliferation
Signal Transduction

Sample Type (Specific)

Cell Extracts

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Cell Analysis
• Clinical
• Drug Discovery & Development

User Ratings

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Description

PAK-1,2,3 [pT402] , Phosphospecific Antibody (SKU# 480025) specific to Rat. This antibody is validated for use in WB. PAK-1,2,3 [pT402] , Phosphospecific Antibody recognizes the   View full product details >

General Specifications

Reactivity

Rat

Validated Application

Western Blot

Host

Rabbit

SubClass (Isotype)

IgG1

Clonality

Polyclonal

Clone ID

pAB

Antibody Fragment

Whole Antibody

Target Gene

PAK1/2/3 [pT402]

Gene ID

29431

Gene Symbol

PAK1

Label or Dye

Unconjugated

Target Modification State

Phospho

Purification

Affinity Purified

Form

Frozen

Product Size

100 µl

Volume

100 µl

Shipping Condition

Wet Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Proteins, Expression, Isolation & Analysis

User Ratings

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Description

The Omnia® kinase assay utilizes peptide substrates incorporating the proprietary SOX moiety to measure phosphorylation in an antibody-free format. This enables the user to   View full product details >

General Specifications

Form

Frozen

Color

Green

Readout

Kinetic

Platform

Microplate Reader

Technique

Fluorescence Intensity

Assay Type

Serine⁄Threonine Kinase Assay

References

Nature Methods Vol 2 pps 277-283 (2005) and JACS Vol 125 pps 14248 - 14249 (2003)

Label or Dye

Sox Chelation-Enhanced Fluorophore

Product Size

1 Kit

Target Enzyme

Serine/Threonine Kinases

Substrate Type

Kinase Substrate

Detection Method

Fluorescent

Molecular Weight

1532.3 Da

Validated Kinases

PAK1, PAK2, PAK3, PAK4, PAK7, PKA, PRKG1, PRKG2, PRKX, ROCK2, RPS6KA5 (MSK1)

Amino Acid Sequence

Ac-GRTGRRNSIdP(Sox)G-NH2

Substrate Properties

Peptide-Based Substrate

Excitation⁄Emission (nm)

360⁄485

Shipping Condition

Dry Ice

Regulatory Statement

For Research Use Only. Not for use in diagnostic procedures.

Product Applications

• Drug Discovery & Development
• Proteins, Expression, Isolation & Analysis

User Ratings

Rate this product