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Genotyping
Human genetic variation is present in many different forms in the genome, ranging from large, structural, chromosomal changes to single nucleotide polymorphisms (SNPs).
BRAF [V599E] Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3849 | 10 µg | 376.00 |
Description
BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of View full product details >
General Specifications
- Mass
-
10 µg
- Gene ID
-
10488, 673
- Species
-
Human
- Target Gene
-
v-raf murine sarcoma viral oncogene homolog B1
- Gene Aliases
-
BRAF V599E
- Kinase Group
-
Ser⁄Thr Kinases: TKL Group
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Serine⁄Threonine Kinases
- Accession Number
-
NP_004324.1, V599E
- Molecular Weight
-
67.1 kDa
- Research Category
-
Oncology
Signal Transduction
- System Compatibility
-
LanthaScreen™ Antibody
Z'-LYTE™
LanthaScreen™ Substrate
- Validated Application
-
Kinase Assay
- Protein Length or Portion (a.a.)
-
aa 416-766
- Protein Tag or Fusion
-
GST Tag
- Tag Position
-
N-Terminal
- Expression
-
Baculovirus
- Kinase Family
-
RAF Kinase Family
- Protein Form
-
Catalytic
Recombinant
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Rate this productBRAF Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3848 | 10 µg | 376.00 |
Description
BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play View full product details >
General Specifications
- Gene ID
-
2353, 673
- Species
-
Human
- Target Gene
-
v-raf murine sarcoma viral oncogene homolog B1
- Gene Aliases
-
BRAF, BRAF1
- Kinase Group
-
Ser⁄Thr Kinases: TKL Group
- Product Size
-
10 µg
- Protein Family
-
Kinases & Inhibitors
- Protein Subtype
-
Serine⁄Threonine Kinases
- Accession Number
-
NP_004324.2
- Molecular Weight
-
113.6 kDa
- Research Category
-
Oncology
Signal Transduction
- System Compatibility
-
Z'-LYTE™
Omnia® Bulk Substrate
LanthaScreen™ Substrate
LanthaScreen™ Antibody
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
RAF Kinase Family
- Protein Form
-
Full Length
Recombinant
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
BRAF Mutation Analysis Reagents
See all Genetic & Chromosome Abnormality Detection Kits
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 4452136 | 1 kit | 992.00 |
Description
The BRAF Mutation Analysis Reagents employ a simple fragment analysis workflow to detect 1% mutant to wild type genomic DNA across 3 common and rare mutations in the BRAF gene View full product details >
General Specifications
- Species
-
Human
- Platform
-
3130xl Genetic Analyzer
3500 Genetic Analyzer
3500xL Genetic Analyzer
- Technique
-
SNP Genotyping (Fragment Analysis-Based)
Shifted Termination Assay (STA)
- PCR Method
-
Multiplex PCR
- Abnormality
-
Gene Mutations
- Target Gene
-
BRAF gene (Codon 600)
- Product Size
-
1 kit
- Reaction Speed
-
Standard
- Detection Method
-
Capillary Electrophoresis
- Genotyping Target
-
SNPs (Known)
- Sample Type (General)
-
DNA
- Sample Type (Specific)
-
DNA (Genomic)
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Diagnostics & Clinical Research
- Gene Expression Analysis & Genotyping
- Sequencing
User Ratings
BRAF Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR6995A | 100 µg | 1250.00 |
Description
BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
BRAF, BRAF1
- Kinase Group
-
Ser⁄Thr Kinases: TKL Group
- Product Size
-
100 µg
- Accession Number
-
NP_004324.2
- Molecular Weight
-
113.6 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
RAF Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
BRAF [V599E] Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PR7304A | 100 µg | 1250.00 |
Description
BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
BRAF V599E
- Kinase Group
-
Ser⁄Thr Kinases: TKL Group
- Product Size
-
100 µg
- Accession Number
-
NP_004324.1, V599E
- Molecular Weight
-
67.1 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
RAF Kinase Family
- Protein Form
-
Catalytic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
BRAF Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4172 | 1 mg | 5400.00 |
Description
BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
BRAF, BRAF1
- Kinase Group
-
Ser⁄Thr Kinases: TKL Group
- Product Size
-
1 mg
- Accession Number
-
NP_004324.2
- Molecular Weight
-
113.6 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
RAF Kinase Family
- Protein Form
-
Full Length
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
BRAF [V599E] Recombinant Human Protein
See all Serine⁄Threonine Kinases
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4173 | 1 mg | 5400.00 |
Description
BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of View full product details >
General Specifications
- Form
-
Frozen
- Species
-
Human
- Gene Aliases
-
BRAF V599E
- Kinase Group
-
Ser⁄Thr Kinases: TKL Group
- Product Size
-
1 mg
- Accession Number
-
NP_004324.1, V599E
- Molecular Weight
-
67.1 kDa
- Research Category
-
Drug Development
- Validated Application
-
Kinase Assay
- Protein Tag or Fusion
-
GST Tag
- Expression
-
Baculovirus
- Kinase Family
-
RAF Kinase Family
- Protein Form
-
Catalytic
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Proteins, Expression, Isolation & Analysis
User Ratings
B-Raf Mouse Monoclonal Antibody (clone 1C1G6A4)
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 375600 | 100 µg | 299.00 |
Description
Mouse anti-B-Raf; Unconjugated Monoclonal antibody specific to Human, Mouse B-Raf. This antibody is validated for use in Western Blot, Immunoassay (ELISA). Anti-B-Raf recognizes View full product details >
General Specifications
- Reactivity
-
Mouse
Human
- Validated Application
-
ELISA
Western Blot
- Host
-
Mouse
- Clonality
-
Monoclonal
- Clone ID
-
1C1G6A4
- Target Gene
-
B-Raf
- Gene ID
-
673
- Label or Dye
-
Unconjugated
- Purification
-
Affinity Purified
- Product Size
-
100 µg
- Shipping Condition
-
Wet Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Yotiao Rabbit Polyclonal Antibody View 2 Citations
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 360300 | 100 µg | 299.00 |
Description
Rabbit anti-Yotiao; Unconjugated Polyclonal antibody specific to Human, Mouse, Rat Yotiao. This antibody is validated for use in Western Blot, Immunoassay (ELISA). Anti-Yotiao View full product details >
General Specifications
- Reactivity
-
Rat
Human
Mouse
- Validated Application
-
ELISA
Western Blot
Immunoprecipitation
- Host
-
Rabbit
- Clonality
-
Polyclonal
- Target Gene
-
Yotiao
- Gene ID
-
10142
- Label or Dye
-
Unconjugated
- Purification
-
Epitope Affinity Purified
- Product Size
-
100 µg
- Shipping Condition
-
Wet Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Cell Analysis
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-pMAP2K1 (pSer217⁄221) Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4813 | 25 µg | 3049.00 |
Description
A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For View full product details >
General Specifications
- Format
-
384-well plate
- Gene ID
-
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
Terbium (Tb)
FITC (Fluorescein)
- Product Size
-
25 µg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
Z′-LYTE® Kinase Assay Kit - Ser/Thr 3 Peptide
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV3176 | 800 × 20 µl assays | 522.00 |
Description
A coumarin and fluorescein-labeled peptide substrate which can be used for kinase screening in an antibody-free format. This peptide is based upon bovine MBP Thr-97 derived View full product details >
General Specifications
- Format
-
384-well plate
- Readout
-
End Point
- Technique
-
FRET
- Assay Type
-
Serine⁄Threonine Kinase Assay
- References
-
BBRC vol. 61, pp 559-563 (1974), JBC, vol 252, p 4888 (1978)
- Label or Dye
-
Coumarin
- Product Size
-
800 × 20 µl assays
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
BRAF, MAPK1, MAPK3, MAPK12, MAPK13, MAP2K1, MAP2K2, MAP3K6, MAP2K8
- Number of Reactions
-
800 Reactions
- Substrate Properties
-
Peptide-Based Substrate
- Protein or Peptide Source
-
Bovine MBP, Thr-97 derived peptide S5
Consensus seq Pro-X-(Ser⁄Thr)-Pro (APRTPGGRR)
- Excitation⁄Emission (nm)
-
405⁄465, 535
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
LanthaScreen® Tb-pMAP2K1 (pSer217⁄221) Antibody Kit
See all TR-FRET Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| PV4814 | 1 mg | 17050.00 |
Description
A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf.
View full product details >
General Specifications
- Format
-
384-well plate
- Gene ID
-
10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
- Readout
-
End Point
- Technique
-
TR-FRET
- Reactivity
-
Human
- Label or Dye
-
Terbium (Tb)
FITC (Fluorescein)
- Product Size
-
1 mg
- Target Enzyme
-
Serine⁄Threonine Kinases
- Validated Kinases
-
BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
- Antibody Molecular Weight
-
150000 Da
- Excitation⁄Emission (nm)
-
340⁄490, 520
- Shipping Condition
-
Dry Ice
- Regulatory Statement
-
For Research Use Only. Not for use in diagnostic procedures.
Product Applications
- Drug Discovery & Development
- Proteins, Expression, Isolation & Analysis
User Ratings
TaqMan® Mutation Detection IPC Reagent Kit
See all Control Primers, Primer⁄Probe Sets & Templates
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 4467538 | 1 kit | 237.00 |
Description
The TaqMan® Mutation Detection IPC Reagent Kit is a set of optional internal positive control reagents that can be duplexed with any TaqMan® Mutation Detection assay to View full product details >
General Specifications
- Species
-
Non-Human
- Includes
-
Control Primer-Probe Set(s) & Template(s)
- Platform
-
StepOnePlus™
7500 System
ViiA™ 7 System
7500 Fast System
- Target Gene
-
exogeneous, non-human DNA target
- Control Type
-
Positive Control
- Label or Dye
-
VIC®
TAMRA
- Product Size
-
1 kit
- Control Template
-
non-human DNA
- Detection Method
-
Primer-Probe Detection
- Sample Type (General)
-
Cells
DNA
FFPE & Fixed Samples
- Shipping Condition
-
Dry Ice
Product Applications
- Diagnostics & Clinical Research
- Gene Expression Analysis & Genotyping
- PCR & Real-Time PCR
