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Gene-Related Products
Bcl-10 Mouse Monoclonal Antibody (clone151), Concentrate
See all Protein Specific Primary Antibodies
| Catalog # | Unit Size | List Price | |
|---|---|---|---|
| 180275 | 1 ml | 291.00 |
Description
This monoclonal antibody reacts with Bcl-10. Bcl-10 is an apoptotic regulatory molecule identified through its direct involvement in t(1;14)(p22;q32) of mucosa-associated lymphoid View full product details >
General Specifications
- Reactivity
-
Human
- Validated Application
-
Immunohistochemistry (FFPE)
- Host
-
Mouse
- Clonality
-
Monoclonal
- Target Gene
-
Bcl-10
- Gene ID
-
8915
- Label or Dye
-
Unconjugated
- Dilution
-
Concentrate Antibody
- Product Size
-
1 ml
- Shipping Condition
-
Wet Ice
- Regulatory Statement
-
For In Vitro Diagnostic Use.
Product Applications
- Cell Analysis
- Diagnostics & Clinical Research
User Ratings
Rate this product180275
ad0411c3a4972a6b77d4beb3f08137e7_CmgtBuyProduct
Bcl10 [pS138] (Mouse monoclonal)
Manual / Product Insert
9f3ad7a14cd3d1cf5d73e8ec7205e7f1_Manuals
A pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus.
Citations & References
- Authors: Yeh PY, Kuo SH, Yeh KH, Chuang SE, Hsu CH, Chang WC, Lin HI, Gao M, Cheng AL,
- Journal: J Biol Chem (2006) 281:167-175
- Product Usage: The purified PCR product (either sense or antisense direction) was cloned into the bicistronic expression vector pIRES2-EGFP (Clontech) or was cloned in-frame into the pRSET vector (a His6-tagged Escherichia coli expression vector; Invitrogen). The Bcl10 C-terminal 27-amino acid deletion mutant was constructed by digesting the Bcl10 gene with BglII and cloning into the pRSET vector.
- ID: PN64786
- Catalog #s
- V35120
bf40d1cbb2ba9fdad19821fc140fa50c_Citations
CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B.
Citations & References
- Authors: Bertin J, Guo Y, Wang L, Srinivasula SM, Jacobson MD, Poyet JL, Merriam S, Du MQ, Dyer MJ, Robison KE, DiStefano PS, Alnemri ES
- Journal: J Biol Chem (2000) 275:41082-41086
- Product Usage:
- ID: PN41720
b24b1810f41d38b55728a9f56b043d35_Citations
Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure.
Citations & References
- Authors: Ruland J, Duncan GS, Elia A, del Barco Barrantes I, Nguyen L, Plyte S, Millar DG, Bouchard D, Wakeham A, Ohashi PS, Mak TW
- Journal: Cell (2001) 104:33-42
- Product Usage:
- ID: PN44662
ddabb258dc2a7d5b5a7204fa68fe522f_Citations
BCL10 mutation does not represent an important pathogenic mechanism in gastric MALT-type lymphoma, and the presence of the API2-MLT fusion is associated with aberrant nuclear BCL10 expression.
Citations & References
- Authors: Maes B; Demunter A; Peeters B; De Wolf-Peeters C
- Journal: Blood 2002 2:1398-1404
- Product Usage: AmpliTaq Gold® Reagents
- ID: PN89883
8d3830df85c910c24ccd213f5e18a1c2_Citations
Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types.
Citations & References
- Authors: Willis TG; Jadayel DM; Du MQ; Peng H; Perry AR; Abdul-Rauf M; Price H; Karran L; Majekodunmi O; Wlodarska I; Pan L; Crook T; Hamoudi R; Isaacson PG; Dyer MJ
- Journal: Cell 1999 1:35-45
- Product Usage: AmpliTaq® DNA Polymerase
- ID: PN94091
37e86b0a26bbd9c74dc5bfe953cac2a8_Citations
Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32).
Citations & References
- Authors: Zhang Q, Siebert R, Yan M, Hinzmann B, Cui X, Xue L, Rakestraw KM, Naeve CW, Beckmann G, Weisenburger DD, Sanger WG, Nowotny H, Vesely M, Callet-Bauchu E, Salles G, Dixit VM, Rosenthal A, Schlegelberger B, Morris SW
- Journal: Nature Genetics (1999) 22:63-68
- Product Usage: Total RNA was prepared from MALT lymphomas, and RT-PCR products of the BCL10 ORF were cloned into pCR2.1 for sequencing. Wildtype and mutant BCL10 cDNAs were subcloned into pcDNA3, and transiently transfected into MCF7 and 293 cells for functional apoptosis assays. The current version of pcDNA3 is pcDNA3.1.
- ID: PN61509
dbf594efeb99abf7e4cfcadb6518730e_Citations
BCL10 is not a major target for frequent loss of 1p in testicular germ cell tumors.
Citations & References
- Authors: Kakinuma H; Habuchi T; Ito T; Mishina M; Sato K; Satoh S; Akao T; Ogawa O; Kato T
- Journal:
- Product Usage: AmpliTaq Gold® Reagents
- ID: PN88639
55a9af419f6612eb59fcd2309144ec38_Citations
T(11;18)(q21;q21) is associated with advanced mucosa-associated lymphoid tissue lymphoma that expresses nuclear BCL10.
Citations & References
- Authors: Liu H; Ye H; Dogan A; Ranaldi R; Hamoudi RA; Bearzi I; Isaacson PG; Du MQ
- Journal: Blood 2001 4:1182-1187
- Product Usage: AmpliTaq® DNA Polymerase
- ID: PN89900
4b45a909df56b2acdfe081ee97a044a1_Citations
Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-κB and MAPK activation to selectively control cytokine production
Citations & References
- Authors: Gross, O; Grupp, C; Steinberg, C; Zimmermann, S; Strasser, D; Hannesschlaeger, N; Reindl, W; Jonsson, H; Huo, HR; Littman, DR; Peschel, C; Yokoyama, WM; Krug, A; Ruland, J
- Journal: BLOOD 2008 6:2421-2428
- Product Usage: SYBR® Green Reagents
- ID: PN95015
82bfe49997498bb32f56bc1949a27eb2_Citations
Auto-Ubiquitination-Induced Degradation of MALT1-API2 Prevents BCL10 Destabilization in t(11;18)(q21;q21)-Positive MALT Lymphoma
Citations & References
- Authors: Noels, H; Somers, R; Liu, HX; Ye, HT; Du, MQ; De Wolf-Peeters, C; Marynen, P; Baens, M
- Journal: PLoS One 2009 3:U45-U56
- Product Usage: Capillary Electrophoresis Systems
- ID: PN101952
12cd0b326e3445d0c19f49c1cdfaaa5d_Citations
CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B.
Citations & References
- Authors: Bertin J, Wang L, Guo Y, Jacobson MD, Poyet JL, Srinivasula SM, Merriam S, DiStefano PS, Alnemri ES
- Journal: J Biol Chem (2001) 276:11877-11882
- Product Usage:
- ID: PN42511
91dacc0f5b8d3192aa89bc86db450dc1_Citations
