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Apaf1 is required for mitochondrial pathways of apoptosis and brain development.
Citations & References
- Authors: Yoshida H, Kong YY, Yoshida R, Elia AJ, Hakem A, Hakem R, Penninger JM, Mak TW
- Journal: Cell (1998) 94:739-750
- Product Usage: Used pCRII to generate a 400 bp Apaf1 cDNA probe using both T7 and SP6 promoters.
- ID: PN65348
- Catalog #s
- K206001
APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.
Citations & References
- Authors: Fortin A, Cregan SP, MacLaurin JG, Kushwaha N, Hickman ES, Thompson CS, Hakim A, Albert PR, Cecconi F, Helin K, Park DS, Slack RS
- Journal: J Cell Biol (2001) 155:207-216
- Product Usage:
- ID: PN45341
Coupling of caspase-9 to Apaf1 in response to loss of pRb or cytotoxic drugs is cell-type-specific.
Citations & References
- Authors: Ho AT, Li QH, Hakem R, Mak TW, Zacksenhaus E
- Journal: EMBO J (2004) 23:460-472
- Product Usage:
- ID: PN55716
- Catalog #s
- M22425
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing.
Citations & References
- Authors: Wang L, Manji GA, Grenier JM, Al-Garawi A, Merriam S, Lora JM, Geddes BJ, Briskin M, DiStefano PS, Bertin J.
- Journal: J Biol Chem (2002) 277:29874-29954
- Product Usage: COS-7L cells were co-transfected in 12-well (22-mm) plates using LipofectAMINE 2000 transfection reagent with plasmids encoding mouse pro-IL-1 and indicated expression plasmids.
- ID: PN62821
- Catalog #s
- 11668019
Faf1 is expressed during neurodevelopment and is involved in Apaf1-dependent caspase-3 activation in proneural cells
Citations & References
- Authors: De Zio, D; Ferraro, E; D'Amelio, M; Simoni, V; Bordi, M; Soroldoni, D; Berghella, L; Meyer, BI; Cecconi, F
- Journal: CELLULAR AND MOLECULAR LIFE SCIENCES 2008 11:1780-1790
- Product Usage: Silencer® siRNAs
- ID: PN81036
Array Plate: Human TNFR1 Pathway (XLS)
Manual / Product Insert
Array Plate: Human Apoptotic Pathways Triggered by HIV1 (XLS)
Manual / Product Insert
Apoptosis Matching TaqMan Assays
Manual / Product Insert
Array Plate: Human c-Myc and Apoptosis (XLS)
Manual / Product Insert
4378701 Plate Info
Manual / Product Insert
Information Card: Human Apoptosis Array
Manual / Product Insert
Brochures & Specifications: TaqMan® Human Apoptosis Array
Product Literature
- Download
- Version: 17 March 2008
Array Plate: Human Apoptosis (XLS)
Manual / Product Insert