Tcr Gamma/Delta

TCR alpha/beta Hamster Anti-Mouse mAb (clone H57-597), Alexa Fluor® 488 Conjugate

Category: Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > Protein Specific Primary Antibodies

TCR ALPHA BETA, Hamster Anti-Mouse, (Alexa Fluor 488); Alexa Fluor 488 conjugated Monoclonal antibody specific to Mouse TCR α/β. This antibody is validated for use in Flow Cytometry. Anti-TCR α/β recognizes the expressed product of the TCRA/B gene.
Catalog: HM3620
Size: 1 ml

PRKCG (PKC gamma) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

The PKC family of serine⁄threonine kinases, including PRKCG (PKC gamma), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PR1467A
Size: 100 µg

PRKCG (PKC gamma) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

The PKC family of serine⁄threonine kinases, including PRKCG (PKC gamma), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3604
Size: 1 mg

PIK3CD⁄PIK3R1 (p110 delta⁄p85 alpha) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Lipid Kinases

PIK3CD (p110 delta) is a class IA PI3K that elicits signaling cascasdes by phosphorylation of the 3 position of PIP2. Unlike the widely expressed Class IA alpha and beta enzymes, the delta isoform is expressed primarily in leukocytes. PIK3CD is coexpressed and copurified with the regulatory subunit PIK3R1.
Catalog: PR9026C
Size: 100 µg

PIK3CD⁄PIK3R1 (p110 delta⁄p85 alpha) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Lipid Kinases

PIK3CD (p110 delta) is a class IA PI3K that elicits signaling cascasdes by phosphorylation of the 3 position of PIP2. Unlike the widely expressed Class IA alpha and beta enzymes, the delta isoform is expressed primarily in leukocytes. PIK3CD is coexpressed and copurified with the regulatory subunit PIK3R1.
Catalog: PV5274
Size: 1 mg

CAMK2D (CaMKII Delta) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CAMK2D (CaMKII delta) is a calmodulin-dependent serine⁄threonine kinase expressed in many cell types. Aberrant expression of CAMK2D has been observed both in tumor cell lines and in the cardiac tissue of patients with dilated cardiomyopathy.
Catalog: PR5448A
Size: 100 µg

CAMK2D (CaMKII Delta) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CAMK2D (CaMKII delta) is a calmodulin-dependent serine⁄threonine kinase expressed in many cell types. Aberrant expression of CAMK2D has been observed both in tumor cell lines and in the cardiac tissue of patients with dilated cardiomyopathy.
Catalog: PV3978
Size: 1 mg

AKT3 (PKB gamma) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

AKT3 (PKB gamma) has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). It is involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, glycogen synthesis and glucose uptake.
Catalog: PR4643B
Size: 100 µg

AKT3 (PKB gamma) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

AKT3 (PKB gamma) has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). It is involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, glycogen synthesis and glucose uptake.
Catalog: PV3976
Size: 1 mg

CAMK1D (CaMKI Delta) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CAMK1D (CaMK1 delta) is a serine⁄threonine kinase that is a member of the calcium⁄calmodulin-dependent protein kinase family. CAMK1D is expressed in polymorphonuclear leukocytes and may be part of the chemokine signal transduction pathway that regulates granulocyte function. It may also be involved in modulation of neuronal apoptosis.
Catalog: PR6770A
Size: 100 µg

CAMK1D (CaMKI Delta) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CAMK1D (CaMK1 delta) is a serine⁄threonine kinase that is a member of the calcium⁄calmodulin-dependent protein kinase family. CAMK1D is expressed in polymorphonuclear leukocytes and may be part of the chemokine signal transduction pathway that regulates granulocyte function. It may also be involved in modulation of neuronal apoptosis.
Catalog: PV3977
Size: 1 mg

PRKCD (PKC delta) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

The PKC family of serine⁄threonine kinases, including PRKCD (PKC delta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PR1464B
Size: 100 µg

PRKCD (PKC delta) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

The PKC family of serine⁄threonine kinases, including PRKCD (PKC delta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3603
Size: 1 mg

PIK3CG (p110 gamma) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Lipid Kinases

PIK3CG (p110 gamma) is the sole class IB phosphatidylinositol 3-kinase family member, which along with the class IA family members, generates the important second messenger PIP2. However, unlike the class IA enzymes which signal downstream of receptor tyrosine kinases, PIK3CG primarily signals downstream of GPCRs.
Catalog: PR8641C
Size: 100 µg

PIK3CG (p110 gamma) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Lipid Kinases

PIK3CG (p110 gamma) is the sole class IB phosphatidylinositol 3-kinase family member, which along with the class IA family members, generates the important second messenger PIP2. However, unlike the class IA enzymes which signal downstream of receptor tyrosine kinases, PIK3CG primarily signals downstream of GPCRs.
Catalog: PV4787
Size: 1 mg

LanthaScreen® TR-FRET ERR gamma Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4408: The LanthaScreen™ TR-FRET Estrogen Related Receptor (ERR) gamma Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential ERR gamma ligands as antagonists/inverse agonists of coactivator displacement. The homogeneous mix-and-read assay format results in a ligand EC50 composite value representing the amount of ligand required to bind to receptor, effect a conformational change, and displace coactivator peptide (Figure 1). How it works The LanthaScreen™ TR...
Catalog: A15121
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET PPAR delta Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4685: The LanthaScreen™ TR-FRET PPAR (peroxisome proliferator activated receptor) delta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential PPAR delta ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant PPAR delta ligand-binding domain (PPAR delta-LBD) that is tagged with glutathione-S-transferase (GST), in a homogeneous ...
Catalog: A15134
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET PPAR delta Competitive Binding Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4893: The LanthaScreen™ TR-FRET PPAR delta Competitive Binding Assay provides a sensitive and robust method for high-throughput screening (HTS) of ligands for peroxisome proliferator-activated receptor delta (PPAR delta). The kit uses a terbium-labeled anti-GST antibody, a fluorescent small-molecule pan-PPAR ligand (Fluormone™ Pan-PPAR Green), and a human PPAR delta ligand-binding domain (LBD) that is tagged with glutathione S-transferase (GST), in a homogeneous mix-and-read assay format. To assay: When r...
Catalog: A15144
Size: 400 × 40 µl assays

LanthaScreen® TR-FRET PPAR gamma Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4548: The LanthaScreen™ TR-FRET PPAR gamma Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential PPAR gamma ligands as agonists or antagonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a Peroxisome Proliferator Activated Receptor (PPAR) gamma ligand-binding domain (PPAR gamma-LBD) that is tagged with glutathione-S-transferase (GST), in a homogenous mix-...
Catalog: A15126
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET PPAR gamma Competitive Binding Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4894: The LanthaScreen™ TR-FRET PPAR gamma Competitive Binding Assay provides a sensitive and robust method for high-throughput screening (HTS) of ligands for peroxisome proliferator-activated receptor-gamma (PPAR gamma). The kit uses a terbium-labeled anti-GST antibody, a fluorescent small-molecule pan-PPAR ligand (Fluormone™ Pan-PPAR Green), and human PPAR gamma ligand-binding domain (LBD) that is tagged with glutathione S-transferase (GST) in a homogeneous mix-and-read assay format. To assay: When runn...
Catalog: A15145
Size: 400 × 40 µl assays