Receptor Assay
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4381: The LanthaScreen™ TR-FRET Androgen Receptor (AR) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential AR ligands as agonists of coactivator recruitment or antagonists of agonist-dependent coactivator recruitment. In both the agonist and antagonist modes, the homogeneous mix-and-read assay uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a rat AR ligand-binding domain (AR-LBD) that is tagged with hexahisti...
Catalog: A15119
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4836: The LanthaScreen™ TR-FRET Constitutive Androstane Receptor (CAR) Coactivator Assay provides a sensitive and robust method for highthroughput screening (HTS) of potential CAR ligands as agonists of ligand-dependent coactivator recruitment or inverse agonists of liganddependent coactivator displacement. The kit uses a terbium-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a CAR ligand-binding domain (CAR-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneo...
Catalog: A15141
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4688: The LanthaScreen™ TR-FRET RAR (retinoic acid receptor) beta Coactivator Assay Kit provides a sensitive and robust method for highthroughput screening of potential RAR beta ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant RAR beta ligand-binding domain (RAR beta-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous, mix-and-read assay format. Wh...
Catalog: A15137
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4411: The LanthaScreen™ TR-FRET Retinoic Acid Receptor (RAR) gamma Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential RAR gamma ligands as agonists of coactivator recruitment. The homogeneous mix-and-read assay format results in a ligand EC50 composite value representing the amount of ligand required to bind to receptor, effect a conformational change, and recruit coactivator peptide (Figure 1). How it works The LanthaScreen™ TR-FRET RAR gamma Coactivat...
Catalog: A15123
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV5889: The LanthaScreen™ TR-FRET Retinoid-related Orphan Receptor alpha (ROR alpha) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential ROR alpha ligands as agonists or inverse agonists of coactivator recruitment. The homogeneous mix-and-read assay uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a ROR alpha ligand-binding domain (ROR alpha-LBD) that is tagged with glutathione-S-transferase (GST).
Catalog: A15146
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV5890: The LanthaScreen™ TR-FRET Retinoid-related Orphan Receptor gamma (ROR gamma) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential ROR gamma ligands as agonists or inverse agonists of coactivator recruitment. The homogeneous mix-and-read assay uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a ROR alpha ligand-binding domain (ROR alpha-LBD) that is tagged with glutathione-S-transferase (GST).
Catalog: A15147
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4797: The LanthaScreen™ TR-FRET Retinoid X Receptor alpha Coactivator Assay provides a sensitive and robust method for high-throughput screening of potential RXR alpha ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti- GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant RXR alpha ligand-binding domain (RXR alpha-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous mix-and-read assay format. To assay: ...
Catalog: A15138
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4385: The LanthaScreen™ TR-FRET Retinoid X Receptor (RXR) beta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential RXR beta ligands as agonists of coactivator recruitment. The homogeneous mix-and-read assay format results in a ligand EC50 composite value representing the amount of ligand required to bind to receptor, effect a conformational change, and recruit coactivator peptide (Figure 1). How it works The LanthaScreen™ TR-FRET RXR beta Coactivator Ass...
Catalog: A15120
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4687: The LanthaScreen™ TR-FRET TR (thyroid receptor) alpha Coactivator Assay Kit provides a sensitive and robust method for highthroughput screening of potential TR alpha ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant TR alpha ligand-binding domain (TR alpha-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous, mix-and-read assay format. To Assay...
Catalog: A15136
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4686: The LanthaScreen™ TR-FRET TR (thyroid receptor) beta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential TR beta ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant TR beta ligand-binding domain (TR beta-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous, mix-and-read assay format. To Assay: W...
Catalog: A15135
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4554: The LanthaScreen™ TR-FRET Vitamin D Receptor (VDR) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential VDR ligands as agonists of coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a VDR ligand-binding domain (VDR-LBD) that is tagged with glutathione-S-transferase (GST), in a homogenous mix-and-read assay format. The assay To run the LanthaScreen™ TR-FRET VDR Coactivator As...
Catalog: A15127
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV6042: The LanthaScreen™ TR-FRET ER beta Competitive Binding Assay provides a sensitive and robust method for high-throughput screening (HTS) of ligands for estrogen receptor beta (ER beta). The kit uses a terbium-labeled anti-GST antibody, a fluorescent small-molecule ER ligand (Fluormone™ ES2), and a human ER beta ligand-binding domain (LBD) that is tagged with glutathione S-transferase (GST), in a homogeneous mix-and-read assay format.
Catalog: A15149
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV6041: The LanthaScreen™ TR-FRET ER alpha Competitive Binding Assay provides a sensitive and robust method for high-throughput screening (HTS) of ligands for estrogen receptor alpha (ER alpha). The kit uses a terbium-labeled anti-GST antibody, a fluorescent small-molecule ER ligand (Fluormone™ ES2), and a human ER alpha ligand-binding domain (LBD) that is tagged with glutathione S-transferase (GST), in a homogeneous mix-and-read assay format.
Catalog: A15150
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV6040: The LanthaScreen™ TR-FRET GR Competitive Binding Assay provides a sensitive and robust method for high-throughput screening (HTS) of ligands for glucocorticoid receptor (GR). The kit uses a terbium-labeled anti-GST antibody, a fluorescent small-molecule GR ligand (Fluormone™ GS1), and a human GR ligand-binding domain (LBD) that is tagged with glutathione S-transferase (GST), in a homogeneous mix-and-read assay format.
Catalog: A15148
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
KDR (VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors.
Catalog: PV3660
Size: 10 µg
Size: 10 µg
Retinoid-related orphan receptor gamma, ligand binding domain (RORG-LBD) is a 58.60 kDa recombinant human protein (amino acids 250-518) expressed as a GST-tagged fusion protein in insect cells. RORG-LBD was expressed and purified in the absence of exogenous ligands, making it ideal for ligand binding and coregulator displacement studies.
Catalog: PV5888
Size: 50 μg
Size: 50 μg
Cluster of Differentiation 44 (CD44), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Pro 220) of human CD44 (P16070-1) fused to a polyhistidine tag at the C-terminus. Activity: This recombinant protein has not been tested. Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0...
Catalog: 12211-H08H-5
Size: 5 µg
Size: 5 µg
Fc gamma receptor III-a (FCGR3A/CD16a), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, studying protein-protein interactions, and cell biology research applications. It can also be used as an immunogen, or as a protein standard. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1- Gln 208) of human FCGR3A (P08637-1) fused to a polyhistidine tag at the C-terminus. Activity: Using the Octet RED System, the affinity constant (Kd) of CD16a bound to Human IgG1 was 180nM. Formulat...
Catalog: 10389-H08H-250
Size: 5 × 50 µg
Size: 5 × 50 µg
Cluster of Differentiation 27 (CD27), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in studying protein-protein interactions, and cell biology research applications. It can also be used as a protein standard. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Ile 192) of human CD27 (NP_001233.1) fused to the polyhistidine-tagged Fc region of human IgG1 at the carboxy-terminus. Activity: Measured by its ability to bind to recombinant human CD70 . Immobilized recombinant human CD27 at 2 µg/ml (100 µl/well) c...
Catalog: 10039-H03H-25
Size: 25 µg
Size: 25 µg
Cluster of Differentiation 27 (CD27), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in studying protein-protein interactions, and cell biology research applications. It can also be used as a protein standard. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Ile 192) of human CD27 (NP_001233.1) fused to the polyhistidine-tagged Fc region of human IgG1 at the carboxy-terminus. Activity: Measured by its ability to bind to recombinant human CD70 . Immobilized recombinant human CD27 at 2 µg/ml (100 µl/well) c...
Catalog: 10039-H03H-250
Size: 5 × 50 µg
Size: 5 × 50 µg
Receptor Assay
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