protein kinase substrate
PKN1 (PRK1) belongs to the protein kinase C superfamily. This kinase is activated by the Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can also be activated by phospholipids.
Catalog: PV3790
Size: 10 µg
Size: 10 µg
MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes.
Catalog: PV4902
Size: 10 µg
Size: 10 µg
This is a purified rabbit anti-human ERK monoclonal antibody (mAb) that can be used in validated applications such as western blotting (WB), indirect ELISA, immunocytochemistry (ICC) and flow cytometry (FC). ABfinity™ antibody characteristics include: • APPLICATIONS: This ERK Monoclonal Antibody, ABfinity™ Recombinant has been validated for use in western blotting, indirect ELISA, immunocytochemistry, and flow cyotmetry. • HOST SPECIES AND ISOTYPE: This is a recombinant rabbit monoclonal IgG against human ERK. • CLONE ID OF MONOCLONAL (mAb): The monoclonal antibody clone is 3H4L13. • REACTIVIT...
Catalog: 701183
Size: 100 µg
Size: 100 µg
This is a purified rabbit anti-human MEK1 oligoclonal antibody that can be use in the validated applications of indirect ELISA, Western blot, and immunocytochemistry. Antibody characteristics include: Applications: This MEK1 Oligoclonal Antibody, ABfinity™ Recombinant has been validated for use in indirect ELISA, Western blot, and immunocytochemistry. Host species and isotype: This is a recombinant rabbit oligoclonal IgG against human MEK1. Clone ID of oligoclonal antibody (mAb): The MEK1 oligoclonal antibody clone is 22HCLC. Reactivity: Along with human MEK1, this oligoclonal antibody is pred...
Catalog: 710446
Size: 100 µg
Size: 100 µg
This is a purified rabbit anti-human COT/TPL2/MAP3K8 monoclonal antibody that can be use in the validated applications of indirect ELISA and Western blot. Antibody characteristics include: Applications: This COT/TPL2/MAP3K8 Monoclonal Antibody, ABfinity™ Recombinant has been validated for use in indirect ELISA and Western blot. Host species and isotype: This is a recombinant rabbit monoclonal IgG against human COT/TPL2/MAP3K8. Clone ID of monoclonal antibody (mAb): The COT/TPL2/MAP3K8 Monoclonal antibody clone is 3H18L5. Reactivity: Along with human COT/TPL2/MAP3K8 , this monoclonal antibody i...
Catalog: 701352
Size: 100 µg
Size: 100 µg
SKP2 (S-phase Kinase-associated Protein 2) belongs to the family of F-box proteins that interact with the Cyclin A-Cdk2 complex. In tumor tissues, SKP2 is expressed widely, such as colon mucinous carcinoma, gastric adenocarcinoma, breast cancer, melanoma, prostate adenocarcinoma, with particularly higher expression on lung adenocarcinoma, lung squamous carcinoma, squamous carcinoma of cervix, endometrial carcinoma, ovary serous carcinoma and leiomyosarcoma. A recent study suggests that SKP2 plays a role in oncogenesis and is involved in the pathogenesis of lymphomas. Positive tissue: Breast ca...
Catalog: 18-7334
Size: 0.5 ml
Size: 0.5 ml
PI4KB and PI4KA are the two human type III PI4 kinases, which share sequence similarly with PI3 kinases and phosphorylate the 4 position of phosphotidyl inositol.
Catalog: PV5277
Size: 20 µg
Size: 20 µg
KDR (VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors.
Catalog: PV3660
Size: 10 µg
Size: 10 µg
EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER.
Catalog: PV5106
Size: 10 µg
Size: 10 µg
CDK8 phosphorylates the carboxy-terminal domain of the largest subunit of RNA polymerase II. This protein is coexpressed and copurified with CyclinC.
Catalog: PV4402
Size: 10 µg
Size: 10 µg
BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrane ser⁄thr kinases which phosphorylates intracellular SMADs in response to bone morphogenic proteins.
Catalog: PV6038
Size: 10 µg
Size: 10 µg
MAPK9 (JNK2) is a serine⁄threonine kinase which plays an important role in the MAPK pathway.
Catalog: PV4018
Size: 1 mg
Size: 1 mg
MAP2K1 (MEK1) kinse is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx.
Catalog: PR5043A
Size: 100 µg
Size: 100 µg
MAP2K1 (MEK1) kinse is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx.
Catalog: PV4003
Size: 1 mg
Size: 1 mg
Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines.
Catalog: PR4375B
Size: 100 µg
Size: 100 µg
Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines.
Catalog: PV4086
Size: 1 mg
Size: 1 mg
STK17A (DRAK1) is a serine⁄threonine kinase localized in the nucleus and involved in apoptosis.
Catalog: PR7034B
Size: 100 µg
Size: 100 µg
STK17A (DRAK1) is a serine⁄threonine kinase localized in the nucleus and involved in apoptosis.
Catalog: PV4061
Size: 1 mg
Size: 1 mg
PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function.
Catalog: PR6347B
Size: 100 µg
Size: 100 µg
PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function.
Catalog: PV4036
Size: 1 mg
Size: 1 mg
protein kinase substrate
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