Products Kits & Assays

LanthaScreen® TR-FRET AR Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4381: The LanthaScreen™ TR-FRET Androgen Receptor (AR) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential AR ligands as agonists of coactivator recruitment or antagonists of agonist-dependent coactivator recruitment. In both the agonist and antagonist modes, the homogeneous mix-and-read assay uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a rat AR ligand-binding domain (AR-LBD) that is tagged with hexahisti...
Catalog: A15119
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET CAR Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4836: The LanthaScreen™ TR-FRET Constitutive Androstane Receptor (CAR) Coactivator Assay provides a sensitive and robust method for highthroughput screening (HTS) of potential CAR ligands as agonists of ligand-dependent coactivator recruitment or inverse agonists of liganddependent coactivator displacement. The kit uses a terbium-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a CAR ligand-binding domain (CAR-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneo...
Catalog: A15141
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET ER alpha Competitive Binding Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV6042: The LanthaScreen™ TR-FRET ER beta Competitive Binding Assay provides a sensitive and robust method for high-throughput screening (HTS) of ligands for estrogen receptor beta (ER beta). The kit uses a terbium-labeled anti-GST antibody, a fluorescent small-molecule ER ligand (Fluormone™ ES2), and a human ER beta ligand-binding domain (LBD) that is tagged with glutathione S-transferase (GST), in a homogeneous mix-and-read assay format.
Catalog: A15149
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET ER beta Competitive Binding Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV6041: The LanthaScreen™ TR-FRET ER alpha Competitive Binding Assay provides a sensitive and robust method for high-throughput screening (HTS) of ligands for estrogen receptor alpha (ER alpha). The kit uses a terbium-labeled anti-GST antibody, a fluorescent small-molecule ER ligand (Fluormone™ ES2), and a human ER alpha ligand-binding domain (LBD) that is tagged with glutathione S-transferase (GST), in a homogeneous mix-and-read assay format.
Catalog: A15150
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET GR Competitive Binding Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV6040: The LanthaScreen™ TR-FRET GR Competitive Binding Assay provides a sensitive and robust method for high-throughput screening (HTS) of ligands for glucocorticoid receptor (GR). The kit uses a terbium-labeled anti-GST antibody, a fluorescent small-molecule GR ligand (Fluormone™ GS1), and a human GR ligand-binding domain (LBD) that is tagged with glutathione S-transferase (GST), in a homogeneous mix-and-read assay format.
Catalog: A15148
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET RAR beta Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4688: The LanthaScreen™ TR-FRET RAR (retinoic acid receptor) beta Coactivator Assay Kit provides a sensitive and robust method for highthroughput screening of potential RAR beta ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant RAR beta ligand-binding domain (RAR beta-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous, mix-and-read assay format. Wh...
Catalog: A15137
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET RAR gamma Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4411: The LanthaScreen™ TR-FRET Retinoic Acid Receptor (RAR) gamma Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential RAR gamma ligands as agonists of coactivator recruitment. The homogeneous mix-and-read assay format results in a ligand EC50 composite value representing the amount of ligand required to bind to receptor, effect a conformational change, and recruit coactivator peptide (Figure 1). How it works The LanthaScreen™ TR-FRET RAR gamma Coactivat...
Catalog: A15123
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET ROR alpha Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV5889: The LanthaScreen™ TR-FRET Retinoid-related Orphan Receptor alpha (ROR alpha) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential ROR alpha ligands as agonists or inverse agonists of coactivator recruitment. The homogeneous mix-and-read assay uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a ROR alpha ligand-binding domain (ROR alpha-LBD) that is tagged with glutathione-S-transferase (GST).
Catalog: A15146
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET ROR gamma Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV5890: The LanthaScreen™ TR-FRET Retinoid-related Orphan Receptor gamma (ROR gamma) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential ROR gamma ligands as agonists or inverse agonists of coactivator recruitment. The homogeneous mix-and-read assay uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a ROR alpha ligand-binding domain (ROR alpha-LBD) that is tagged with glutathione-S-transferase (GST).
Catalog: A15147
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET RXR alpha Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4797: The LanthaScreen™ TR-FRET Retinoid X Receptor alpha Coactivator Assay provides a sensitive and robust method for high-throughput screening of potential RXR alpha ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti- GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant RXR alpha ligand-binding domain (RXR alpha-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous mix-and-read assay format. To assay: ...
Catalog: A15138
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET RXR beta Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4385: The LanthaScreen™ TR-FRET Retinoid X Receptor (RXR) beta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential RXR beta ligands as agonists of coactivator recruitment. The homogeneous mix-and-read assay format results in a ligand EC50 composite value representing the amount of ligand required to bind to receptor, effect a conformational change, and recruit coactivator peptide (Figure 1). How it works The LanthaScreen™ TR-FRET RXR beta Coactivator Ass...
Catalog: A15120
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET TR alpha Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4687: The LanthaScreen™ TR-FRET TR (thyroid receptor) alpha Coactivator Assay Kit provides a sensitive and robust method for highthroughput screening of potential TR alpha ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant TR alpha ligand-binding domain (TR alpha-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous, mix-and-read assay format. To Assay...
Catalog: A15136
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET TR beta Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4686: The LanthaScreen™ TR-FRET TR (thyroid receptor) beta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential TR beta ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant TR beta ligand-binding domain (TR beta-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous, mix-and-read assay format. To Assay: W...
Catalog: A15135
Size: 800 × 20 µl assays

LanthaScreen® TR-FRET VDR Coactivator Assay Kit (Rabbit)

Category: Products & Services > Kits & Assays > Biochemical Assay Kits > Nuclear Receptor Biochemical Assays

This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4554: The LanthaScreen™ TR-FRET Vitamin D Receptor (VDR) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential VDR ligands as agonists of coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a VDR ligand-binding domain (VDR-LBD) that is tagged with glutathione-S-transferase (GST), in a homogenous mix-and-read assay format. The assay To run the LanthaScreen™ TR-FRET VDR Coactivator As...
Catalog: A15127
Size: 800 × 20 µl assays

KIT [V654A] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. The clinically observed V654A mutant has been demonstrated to be resistant to inhibition with imatinib.
Catalog: PR7738A
Size: 100 µg

KIT [V654A] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. The clinically observed V654A mutant has been demonstrated to be resistant to inhibition with imatinib.
Catalog: PV4291
Size: 1 mg

KIT Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis.
Catalog: PR4460D
Size: 100 µg

KIT Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis.
Catalog: PV3589
Size: 1 mg

KIT [T670I] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. KIT T670I is a Gleevec resistant form of KIT.
Catalog: PR7423A
Size: 100 µg

KIT [T670I] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. KIT T670I is a Gleevec resistant form of KIT.
Catalog: PV4187
Size: 1 mg