P53 Apoptosis
The Vybrant Apoptosis Assay Kit #4 detects apoptosis on the basis of changes that occur in the permeability of cell membranes. This kit contains ready-to-use solutions of both YO-PRO-1 and propidium iodide nucleic acid stains. YO-PRO-1 stain selectively passes through the plasma membranes of apoptotic cells and labels them with moderate green fluorescence. Necrotic cells are stained red-fluorescent with propidium iodide.
Catalog: V13243
Size: 1 kit
Size: 1 kit
The Violet Ratiometric Membrane Asymmetry Probe⁄Dead Cell Apoptosis Kit provides a simple and fast method for the detection of apoptosis with dead cell discrimination by flow cytometry. The Violet Ratiometric Membrane Asymmetry Probe, 4'-N,N-diethylamino-6-(N,N,N-dodecyl-methylamino-sulfopropyl)-methyl-3-hydroxyflavone (F2N12S), is a novel violet excitable dye for the detection of membrane asymmetry changes during apoptosis. The dye exhibits an excited-state intramolecular proton transfer (ESIPT) reaction resulting in a dual fluorescence with two emission bands corresponding to 530 nm and 585 ...
Catalog: A-35137
Size: 1 kit
Size: 1 kit
These 96-well plates are pre-configured with the most appropriate TaqMan® Gene Expression Assays for a specific biological process, pathway, or disease state. Each plate contains predefined assays and endogenous controls dried-down in the wells, ready for accurate assessment of an entire gene signature in one simple experiment. The TaqMan® Array Human p53 Signaling 96-well Plate contains 92 assays to p53 signaling associated genes and 4 assays to candidate endogenous control genes.
Catalog: 4418813
Size: 1 Fast plate
Size: 1 Fast plate
Tumor protein p53 (P53), recombinant cynomolgus protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the cynomolgus ( Macaca fascicularis ) P53 (E3U906) (Met 1-Asp 393). Activity: 1. Measured by its ability to bind biotinylated human S100B in a functional ELISA. 2. Measured by its ability to bind...
Catalog: 90001-CNAE-25
Size: 5 × 5 µg
Size: 5 × 5 µg
Tumor protein p53 (P53), recombinant cynomolgus protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the cynomolgus ( Macaca fascicularis ) P53 (E3U906) (Met 1-Asp 393). Activity: 1. Measured by its ability to bind biotinylated human S100B in a functional ELISA. 2. Measured by its ability to bind...
Catalog: 90001-CNAE-250
Size: 5 × 50 µg
Size: 5 × 50 µg
Tumor protein p53 (P53), recombinant cynomolgus protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the cynomolgus ( Macaca fascicularis ) P53 (E3U906) (Met 1-Asp 393). Activity: 1. Measured by its ability to bind biotinylated human S100B in a functional ELISA. 2. Measured by its ability to bind...
Catalog: 90001-CNAE-5
Size: 5 µg
Size: 5 µg
Tumor protein p53 (P53), recombinant cynomolgus protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the cynomolgus ( Macaca fascicularis ) P53 (E3U906) (Met 1-Asp 393). Activity: 1. Measured by its ability to bind biotinylated human S100B in a functional ELISA. 2. Measured by its ability to bind...
Catalog: 90001-CNAE-50
Size: 50 µg
Size: 50 µg
The Ion AmpliSeq™ RNA Apoptosis Panel is a screening tool designed against 267 genes involved in the cellular apoptosis pathway. Included are genes associated with death receptor-mediated apoptosis, c-Myc, and p53-mediated apoptosis. • Measure gene expression fold changes between samples • Amplicons are designed to be most inclusive for transcripts of the target gene • Each reaction requires only 500 pg of unfixed RNA or 5 ng of fixed (FFPE) RNA • Prepare amplicon libraries with the Ion AmpliSeq™ RNA Library Kit and sequence on the Ion Personal Genome Machine® (PGM™) or Ion Proton™ system This...
Catalog: 4482571
Size: 24 reactions
Size: 24 reactions
The ApoTarget™ APO-BRDU Kit is a two-color staining method for labeling DNA breaks and total cellular DNA to detect apoptotic cells by flow cytometry.
Catalog: KHO1001
Size: 60 tests
Size: 60 tests
The ApoTarget™ Quick Apoptotic DNA Ladder Detection Kit provides a simple and rapid procedure for extraction of chromosomal DNA. The procedure prepares DNA for use in the methods that detect DNA fragmentation in apoptotic cells. Unlike other kits requiring 1 to 2 days to finish, this detection method requires only less than 90 minutes to prepare DNA in a single tube without the need for extraction or column steps. DNA fragmentation can be easily visualized by agarose gel electrophoresis. This procedure increases recovery of small fragmented DNA, thereby improving the sensitivity of the assay.
Catalog: KHO1021
Size: 50 tests
Size: 50 tests
The CellEvent™ Caspase-3/7 Green Flow Cytometry Assay Kit enables the flow cytometric detection of activated caspase-3 and caspase-7 in apoptotic cells. The kit includes the novel fluorogenic substrate CellEvent® Caspase-3/7 Green Detection Reagent, as well as SYTOX® AADvanced™ Dead Cell Stain. • Caspase-3/7 specific—includes the recognition sequence for activated caspase-3 and caspase-7 • Easy identification—clearly identify live, dead, and apoptotic cell populations • Quick analysis—washing and fixation is not required • Multicolor compatibility—combine with other dyes excitable by the 488 n...
Catalog: C10427
Size: 100 assays
Size: 100 assays
CellEvent® Caspase-3/7 Green ReadyProbes™ Reagent is a fluorogenic, no-wash indicator of activated caspase-3/7 for live- and fixed-cell applications. Activation of caspase-3 is an early indicator of apoptosis and CellEvent® Caspase-3/7 Green reagent allows rapid and sensitive detection of cells destined for cell death. Like other ReadyProbes™ reagents, CellEvent™ Caspase-3/7 Green reagent is formulated as a room temperature-stable solution and comes in a convenient dropper bottle. Just tip and drip two drops per ml to stain your cells. CellEvent™ Caspase-3/7 Green ReadyProbes™ Reagent provides...
Catalog: R37111
Size: 1 kit
Size: 1 kit
This is a purified rabbit anti-human Casp3 oligoclonal antibody that can be use in the validated applications of indirect ELISA and Western blot. Antibody characteristics include: Applications: This Casp3 Oligoclonal Antibody, ABfinity™ Recombinant has been validated for use in indirect ELISA and Western blot. Host species and isotype: This is a recombinant rabbit oligoclonal IgG against human Casp3. Clone ID of oligoclonal antibody (mAb): The Casp3 oligoclonal antibody clone is 22HCLC. Reactivity: Along with human Casp3, this oligoclonal antibody is predicted to react with monkey, dog, rabbit...
Catalog: 710431
Size: 100 µg
Size: 100 µg
P53 Apoptosis
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