Lipid Assay
PI4KB and PI4KA are the two human type III PI4 kinases, which share sequence similarly with PI3 kinases and phosphorylate the 4 position of phosphotidyl inositol.
Catalog: PV5277
Size: 20 µg
Size: 20 µg
The Class II PI3 kinases, including PIK3C2A, phosphorylate the 3 position of PI or PI4P. Though not as well studied as the Class I PI3 kinases, the Class II enyzmes have been linked to diverse, recpetor-mediated cellular processes including insulin signalling, neuronal survival, and growth factor signalling.
Catalog: PR9053A
Size: 100 µg
Size: 100 µg
SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signalling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapuetics for the treatment of cancer.
Catalog: PV5215
Size: 1 mg
Size: 1 mg
PIK3CG (p110 gamma) is the sole class IB phosphatidylinositol 3-kinase family member, which along with the class IA family members, generates the important second messenger PIP2. However, unlike the class IA enzymes which signal downstream of receptor tyrosine kinases, PIK3CG primarily signals downstream of GPCRs.
Catalog: PR8641C
Size: 100 µg
Size: 100 µg
PIK3CG (p110 gamma) is the sole class IB phosphatidylinositol 3-kinase family member, which along with the class IA family members, generates the important second messenger PIP2. However, unlike the class IA enzymes which signal downstream of receptor tyrosine kinases, PIK3CG primarily signals downstream of GPCRs.
Catalog: PV4787
Size: 1 mg
Size: 1 mg
The intracellular accumulation of neutral lipids, steatosis, is often triggered by drugs that affect the metabolism of fatty acids and/or neutral lipids. HCS LipidTOX™ Red neutral lipid stain was developed to characterize the potentially toxic effects of compounds on lipid metabolism in mammalian cell lines. The LipidTOX™ neutral lipid stain has an extremely high affinity for neutral lipid droplets and can be detected by fluorescence microscopy or an HCS reader. This probe is compatible with the HCS LipidTOX™ phospholipidosis detection reagents (H34350, H34351). HCS LipidTOX™ neutral lipid sta...
Catalog: H34476
Size: 1 each
Size: 1 each
Lipid Assay
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