Lanthascreen™ Sumo Products
Chemokine (C-C Motif) Ligand 8 (CCL8), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the human CCL8 (P80075-1) (Gln 24-Pro 99) fused to the SUMO tag at the N-terminus. Activity: The activity of this protein has not been tested. Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween80. Reconstitution:...
Catalog: 10989-H21E-5
Size: 5 µg
Size: 5 µg
The Champion™ pET SUMO Expression System produces the highest levels of soluble protein in E. coli . It utilizes a small ubiquitin-related modifier (SUMO) fusion, belonging to the growing family of ubiquitin-related proteins, to enhance the solubility of expressed fusion proteins. In contrast to ubiquitin, SUMO is involved in the stabilization and localization of proteins in vivo . After expression, the 11 kd SUMO moiety can be cleaved by the highly specific and active SUMO (ULP-1) protease at the carboxyl terminal, producing a native protein*. The Champion™ pET SUMO Protein and Peptide Expres...
Catalog: K300-01
Size: 20 reactions
Size: 20 reactions
Chemokine (C-C Motif) Ligand 8 (CCL8), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the human CCL8 (P80075-1) (Gln 24-Pro 99) fused to the SUMO tag at the N-terminus. Activity: The activity of this protein has not been tested. Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween80. Reconstitution:...
Catalog: 10989-H21E-25
Size: 5 × 5 µg
Size: 5 × 5 µg
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4381: The LanthaScreen™ TR-FRET Androgen Receptor (AR) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential AR ligands as agonists of coactivator recruitment or antagonists of agonist-dependent coactivator recruitment. In both the agonist and antagonist modes, the homogeneous mix-and-read assay uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a rat AR ligand-binding domain (AR-LBD) that is tagged with hexahisti...
Catalog: A15119
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4544: The LanthaScreen™ TR-FRET ER alpha Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential estrogen receptor (ER) alpha ligands as agonists or antagonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and an ER alpha ligand-binding domain (ER alpha-LBD) that is tagged with glutathione-S-transferase (GST), in a homogenous mix-and-read assay format. Agonist m...
Catalog: A15125
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4541: The LanthaScreen™ TR-FRET Estrogen Receptor beta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential ER beta ligands as agonists or antagonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a ER beta ligand-binding domain (ER beta-LBD) that is tagged with glutathione-S-transferase (GST), in a homogenous mix-and-read assay format. Agonist mode To run...
Catalog: A15124
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4663: The LanthaScreen™ ERR (estrogen related receptor) alpha TR-FRET Coactivator Assay provides a sensitive and robust method for high-throughput screening of potential ERR alpha ligands as inverse agonists (sometimes referred to as antagonists) of coactivator displacement. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and an ERR alpha ligand-binding domain (ERR alpha-LBD) that is tagged with glutathione-S-transferase (GST), in a homogeneous mix-and-rea...
Catalog: A15130
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4408: The LanthaScreen™ TR-FRET Estrogen Related Receptor (ERR) gamma Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential ERR gamma ligands as antagonists/inverse agonists of coactivator displacement. The homogeneous mix-and-read assay format results in a ligand EC50 composite value representing the amount of ligand required to bind to receptor, effect a conformational change, and displace coactivator peptide (Figure 1). How it works The LanthaScreen™ TR...
Catalog: A15121
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4683: The LanthaScreen™ TR-FRET GR (glucocorticoid receptor) Coactivator Assay provides a sensitive and robust method for high-throughput screening of potential GR ligands as agonists or antagonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant GR ligand-binding domain (GR-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous mix-and-read assay format. Agonist mode: ...
Catalog: A15132
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4655: The LanthaScreen™ TR-FRET LXR (liver X receptor) alpha Coactivator Assay provides a sensitive and robust method for high-throughput screening of potential LXR alpha ligands as agonists of coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and an LXR alpha ligand-binding domain (LBD) that is tagged with glutathione-S-transferase (GST), in a homogeneous mix-and-read assay format. In the LanthaScreen™ TR-FRET LXR alpha Coactivator ...
Catalog: A15128
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4684: The LanthaScreen™ TR-FRET PPAR (peroxisome proliferator activated receptor) alpha Coactivator Assay provides a sensitive and robust method for high-throughput screening of potential PPAR alpha ligands as agonists or antagonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant PPAR alpha ligand-binding domain (PPAR alpha-LBD) that is tagged with glutathione-S-transferase (GST) in a ho...
Catalog: A15133
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4685: The LanthaScreen™ TR-FRET PPAR (peroxisome proliferator activated receptor) delta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential PPAR delta ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant PPAR delta ligand-binding domain (PPAR delta-LBD) that is tagged with glutathione-S-transferase (GST), in a homogeneous ...
Catalog: A15134
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4548: The LanthaScreen™ TR-FRET PPAR gamma Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential PPAR gamma ligands as agonists or antagonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a Peroxisome Proliferator Activated Receptor (PPAR) gamma ligand-binding domain (PPAR gamma-LBD) that is tagged with glutathione-S-transferase (GST), in a homogenous mix-...
Catalog: A15126
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4666: The LanthaScreen™ TR-FRET PR (Progesterone Receptor) Coactivator Assay provides a sensitive and robust method for high-throughput screening of potential PR ligands as agonists or antagonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a PR ligand--binding domain (PR-LBD) that is tagged with glutathione-S-transferase (GST), in a homogenous mix-and-read assay format. When using the LanthaScreen™ TR-F...
Catalog: A15131
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4409: The LanthaScreen™ TR-FRET Retinoic Acid Receptor (RAR) alpha Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential RAR alpha ligands as agonists of coactivator recruitment. The homogeneous mix-and-read assay format results in a ligand EC50 composite value representing the amount of ligand required to bind to receptor, effect a conformational change, and recruit coactivator peptide (Figure 1). How it works The LanthaScreen™ TR-FRET RAR alpha Coactivat...
Catalog: A15122
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4411: The LanthaScreen™ TR-FRET Retinoic Acid Receptor (RAR) gamma Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential RAR gamma ligands as agonists of coactivator recruitment. The homogeneous mix-and-read assay format results in a ligand EC50 composite value representing the amount of ligand required to bind to receptor, effect a conformational change, and recruit coactivator peptide (Figure 1). How it works The LanthaScreen™ TR-FRET RAR gamma Coactivat...
Catalog: A15123
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV5890: The LanthaScreen™ TR-FRET Retinoid-related Orphan Receptor gamma (ROR gamma) Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential ROR gamma ligands as agonists or inverse agonists of coactivator recruitment. The homogeneous mix-and-read assay uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a ROR alpha ligand-binding domain (ROR alpha-LBD) that is tagged with glutathione-S-transferase (GST).
Catalog: A15147
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4385: The LanthaScreen™ TR-FRET Retinoid X Receptor (RXR) beta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential RXR beta ligands as agonists of coactivator recruitment. The homogeneous mix-and-read assay format results in a ligand EC50 composite value representing the amount of ligand required to bind to receptor, effect a conformational change, and recruit coactivator peptide (Figure 1). How it works The LanthaScreen™ TR-FRET RXR beta Coactivator Ass...
Catalog: A15120
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
This kit contains Rabbit Tb-Anti-GST antibody; other kit components are the same as kit PV4686: The LanthaScreen™ TR-FRET TR (thyroid receptor) beta Coactivator Assay Kit provides a sensitive and robust method for high-throughput screening of potential TR beta ligands as agonists of ligand-dependent coactivator recruitment. The kit uses a terbium (Tb)-labeled anti-GST antibody, a fluorescein-labeled coactivator peptide, and a human recombinant TR beta ligand-binding domain (TR beta-LBD) that is tagged with glutathione-S-transferase (GST) in a homogeneous, mix-and-read assay format. To Assay: W...
Catalog: A15135
Size: 800 × 20 µl assays
Size: 800 × 20 µl assays
LanthaScreen® europium-labeled anti-GST rabbit antibodies are used to indirectly label proteins tagged with GST. This can be advantageous when working with partially purified protein, or in cases in which direct labeling of the protein using amine-reactive Eu chelates negatively impacts protein activity. These antibodies can be used with our Kinase Tracers to conduct LanthaScreen® Eu Kinase Binding Assays.
Catalog: A15116
Size: 100 µg
Size: 100 µg
Lanthascreen™ Sumo Products
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