Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER.
Catalog: PV5106
Size: 10 µg
Category: Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > Protein Specific Primary Antibodies
This is a purified rabbit anti-human ERK monoclonal antibody (mAb) that can be used in validated applications such as western blotting (WB), indirect ELISA, immunocytochemistry (ICC) and flow cytometry (FC). ABfinity™ antibody characteristics include: • APPLICATIONS: This ERK Monoclonal Antibody, ABfinity™ Recombinant has been validated for use in western blotting, indirect ELISA, immunocytochemistry, and flow cyotmetry. • HOST SPECIES AND ISOTYPE: This is a recombinant rabbit monoclonal IgG against human ERK. • CLONE ID OF MONOCLONAL (mAb): The monoclonal antibody clone is 3H4L13. • REACTIVIT...
Catalog: 701183
Size: 100 µg
Category: Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > Protein Specific Primary Antibodies
SKP2 (S-phase Kinase-associated Protein 2) belongs to the family of F-box proteins that interact with the Cyclin A-Cdk2 complex. In tumor tissues, SKP2 is expressed widely, such as colon mucinous carcinoma, gastric adenocarcinoma, breast cancer, melanoma, prostate adenocarcinoma, with particularly higher expression on lung adenocarcinoma, lung squamous carcinoma, squamous carcinoma of cervix, endometrial carcinoma, ovary serous carcinoma and leiomyosarcoma. A recent study suggests that SKP2 plays a role in oncogenesis and is involved in the pathogenesis of lymphomas. Positive tissue: Breast ca...
Catalog: 18-7334
Size: 0.5 ml
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
The casein kinase I (CKI) gene family encodes serine⁄threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric and range from 25 to 55 kD. They are ubiquitous, being found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells
Catalog: PR7474A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
The casein kinase I (CKI) gene family encodes serine⁄threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric and range from 25 to 55 kD. They are ubiquitous, being found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells
Catalog: PV3991
Size: 1 mg
Category: Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > Protein Specific Primary Antibodies
This is a purified mouse anti-human ICAM-3 Monoclonal Antibody, FITC conjugate, that can be used in the validated application of flow cytometry. This ICAM-3 Monoclonal Antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant human ICAM-3, and conjugated with FITC under optimum conditions. The unreacted FITC was removed. Antibody characteristics include: Applications: This ICAM-3 Monoclonal Antibody has been validated for use in flow cytometry Host species and isotype: This is a mouse Monoclonal I...
Catalog: 10333-MM02F-AB
Size: 100 tests
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
KDR (VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors.
Catalog: PV3660
Size: 10 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines.
Catalog: PR4375B
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines.
Catalog: PV4086
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
SRMS (Srm) is a tyrosine protein kinase (SRC sub-family) that may be involved in the proliferation and differentiation of keratinocytes.
Catalog: PR7031A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
SRMS (Srm) is a tyrosine protein kinase (SRC sub-family) that may be involved in the proliferation and differentiation of keratinocytes.
Catalog: PV4287
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
FLT4 (VEGFR3), a receptor tyrosine kinase, is a key regulator of embryonic blood vessel development and adult angiogenesis. This kinase has been implicated in juvenile hemangioma, kaposi sarcoma, lymphangiomas, and hereditary lymphedemia.
Catalog: PR7216B
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
FLT4 (VEGFR3), a receptor tyrosine kinase, is a key regulator of embryonic blood vessel development and adult angiogenesis. This kinase has been implicated in juvenile hemangioma, kaposi sarcoma, lymphangiomas, and hereditary lymphedemia.
Catalog: PV4290
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
MATK (Hyl) is a non-receptor CSK-type protein tyrosine kinase that is thought to function in signal transduction pathways important in megakaryocyte growth and⁄or differentiation.
Catalog: PR5045A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
MATK (Hyl) is a non-receptor CSK-type protein tyrosine kinase that is thought to function in signal transduction pathways important in megakaryocyte growth and⁄or differentiation.
Catalog: PV4084
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
FYN is a SRC-related kinase expressed in brain, skeletal muscle and adipose tissues. Fyn functions in a large number of pathways and has been shown to play a role in memory.
Catalog: PR4163A
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
FYN is a SRC-related kinase expressed in brain, skeletal muscle and adipose tissues. Fyn functions in a large number of pathways and has been shown to play a role in memory.
Catalog: PR4163D
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
LCK is a SRC-related kinase family expressed in lymphocytes.
Catalog: PR4170A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
LCK is a SRC-related kinase family expressed in lymphocytes.
Catalog: PV4081
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases
SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth. SRCN1 is a neuronal splice variant of SRC.
Catalog: PR2886A
Size: 100 µg