Products from Ntrk3 (Trkc) Recombinant Human Protein to Mark2 Recombinant Human Protein
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system.
Catalog: PV4116
Size: 1 mg
Size: 1 mg
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family.
Catalog: PV4117
Size: 1 mg
Size: 1 mg
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA T674I is a Gleevec resistant form of PDGFRA.
Catalog: PV4118
Size: 1 mg
Size: 1 mg
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement.
Catalog: PV4119
Size: 1 mg
Size: 1 mg
ROS1 is a tyrosine kinase that functions as a growth or differentiation factor receptor.
Catalog: PV4120
Size: 1 mg
Size: 1 mg
TYRO3 is a receptor tyrosine kinase that has been shown to be involved in signal transduction and cell adhesion.
Catalog: PV4121
Size: 1 mg
Size: 1 mg
GRK7 is a serine⁄threonine kinase that is specifically expressed in the retina and phosphorylates cone opsins and initiates their deactivation.
Catalog: PV4125
Size: 1 mg
Size: 1 mg
BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron.
Catalog: PV4172
Size: 1 mg
Size: 1 mg
BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of cancers.
Catalog: PV4173
Size: 1 mg
Size: 1 mg
CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, which encodes serine⁄threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric, ranging from 25 to 55 kD, and are found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells.
Catalog: PV4174
Size: 1 mg
Size: 1 mg
MARK4 is a serine⁄threonine kinase that is likely to be directly involved in microtubule organization in neuronal cells.
Catalog: PV4175
Size: 1 mg
Size: 1 mg
HIPK4 is a homeodomain-interacting protein kinase and has been demonstrated to phosphorylate p53.
Catalog: PV4176
Size: 1 mg
Size: 1 mg
STK4 (MST1) is a serine⁄threonine kinase which may be involved in apoptosis. It is possible that this protein induces the chromatin condensation observed in this process.
Catalog: PV4177
Size: 1 mg
Size: 1 mg
AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome⁄spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction.
Catalog: PV4178
Size: 1 mg
Size: 1 mg
ROR2 (receptor tyrosine kinase-like orphan receptor 2) is a type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. It is throught to be involved in the early formation of the chondrocytes and cartilage and growth plate development.
Catalog: PV4179
Size: 1 mg
Size: 1 mg
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The Y253F mutant is a Gleevec resistant form of ABL1.
Catalog: PV4181
Size: 1 mg
Size: 1 mg
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The E255K mutant is a Gleevec resistant form of ABL1.
Catalog: PV4182
Size: 1 mg
Size: 1 mg
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The G250E mutant is a Gleevec resistant form of ABL1.
Catalog: PV4183
Size: 1 mg
Size: 1 mg
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The T315I mutant is a Gleevec resistant form of ABL1.
Catalog: PV4184
Size: 1 mg
Size: 1 mg
The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Catalog: PV4186
Size: 1 mg
Size: 1 mg
KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. KIT T670I is a Gleevec resistant form of KIT.
Catalog: PV4187
Size: 1 mg
Size: 1 mg
DDR2 is a member of a subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. DDR1 and DDR2 have been shown to be potently inhibited by Gleevec.
Catalog: PV4188
Size: 1 mg
Size: 1 mg
Dual-specificity kinases, such as DYRK4, play key roles in cell proliferation, survival, and development.
Catalog: PV4189
Size: 1 mg
Size: 1 mg
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics.
Catalog: PV4190
Size: 1 mg
Size: 1 mg
The epidermal growth factor receptor is a receptor tyrosine kinase that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L861Q mutation is an Iressa-responsive mutant observed in the clinic.
Catalog: PV4191
Size: 1 mg
Size: 1 mg
FRK (PTK5) is a nuclear protein and may function during G1 and S phase of the cell cycle, suppressing growth.
Catalog: PV4192
Size: 1 mg
Size: 1 mg
ITK is a tyrosine kinase expressed in T-cells which contains both SH2 and SH3 domains. ITK is thought to play a role in T-cell proliferation and differentiation.
Catalog: PV4193
Size: 1 mg
Size: 1 mg
MAP3K3 (MEKK3) directly regulates MAPK8 and extracellular signal-regulated protein kinase (ERK) pathways by phosphorylating multiple MAP2Ks.
Catalog: PV4194
Size: 1 mg
Size: 1 mg
MAP3K10 (MLK2) is a serine⁄threonine kinase which has been shown to activate MAPK8⁄JNK and MKK4⁄SEK1. This kinase itself can be phoshorylated, and is thus activated by JNK kinases. MAP3K10 functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Catalog: PV4195
Size: 1 mg
Size: 1 mg
MARK2 is a serine⁄threonine protein kinase involved in the control of cell polarity and microtubule stability.
Catalog: PV4196
Size: 1 mg
Size: 1 mg
Products from Ntrk3 (Trkc) Recombinant Human Protein to Mark2 Recombinant Human Protein
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