Products from Prkci (Pkc Iota) Recombinant Human Protein to Dyrk3 Recombinant Human Protein
The PKC family of serine⁄threonine kinases, including PRKCI (PKC iota), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3607
Size: 1 mg
Size: 1 mg
The PKC family of serine⁄threonine kinases, including PRKCH (PKC eta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3608
Size: 1 mg
Size: 1 mg
The PKC family of serine⁄threonine kinases, including PRKCE (PKC epsilon), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3609
Size: 1 mg
Size: 1 mg
KDR (VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors.
Catalog: PV3660
Size: 10 µg
Size: 10 µg
PKN1 (PRK1) belongs to the protein kinase C superfamily. This kinase is activated by the Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can also be activated by phospholipids.
Catalog: PV3790
Size: 10 µg
Size: 10 µg
ADRBK2, or adrenergic beta receptor kinase 2 is a serine⁄threonine kinase that is thought to act as a regulator of receptor function.
Catalog: PV3974
Size: 1 mg
Size: 1 mg
AKT2 is a phosphoinositide-dependent serine⁄threonine protein kinase that is enriched in insulin responsive tissues and has been implicated in the metabolic actions of the hormone.
Catalog: PV3975
Size: 1 mg
Size: 1 mg
AKT3 (PKB gamma) has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). It is involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, glycogen synthesis and glucose uptake.
Catalog: PV3976
Size: 1 mg
Size: 1 mg
CAMK1D (CaMK1 delta) is a serine⁄threonine kinase that is a member of the calcium⁄calmodulin-dependent protein kinase family. CAMK1D is expressed in polymorphonuclear leukocytes and may be part of the chemokine signal transduction pathway that regulates granulocyte function. It may also be involved in modulation of neuronal apoptosis.
Catalog: PV3977
Size: 1 mg
Size: 1 mg
CAMK2D (CaMKII delta) is a calmodulin-dependent serine⁄threonine kinase expressed in many cell types. Aberrant expression of CAMK2D has been observed both in tumor cell lines and in the cardiac tissue of patients with dilated cardiomyopathy.
Catalog: PV3978
Size: 1 mg
Size: 1 mg
CAMK4 (CaMKIV) is a serine⁄threonine protein kinase that phosphoryates CREB, oncoprotein 18, and SRF. It has limited tissue distribution, and has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
Catalog: PV3979
Size: 1 mg
Size: 1 mg
CDK1 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF). It is essential for G1⁄S and G2⁄M phase transitions of the eukaryotic cell cycle, and plays important regulatory roles in cell cycle control. This protein is coexpressed and copurified with CyclinB.
Catalog: PV3980
Size: 1 mg
Size: 1 mg
CDK5 is a cyclin-dependent kinase that plays a critical role in neuron development. The kinase is strongly activated when it complexes with neuron-specific activators, especially p35, but less strongly when it complexes with cyclins. This protein is coexpressed and copurified with p35.
Catalog: PV3981
Size: 1 mg
Size: 1 mg
CHEK1 (CHK1) is a serine⁄threonine protein kinase involved in preventing replication when DNA integrity is compromised.
Catalog: PV3982
Size: 1 mg
Size: 1 mg
CHEK2 (CHK2) is a serine⁄threonine kinase and a component of the DNA damage checkpoint pathway. A mutation in this gene has been linked to cancer. CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins.
Catalog: PV3983
Size: 1 mg
Size: 1 mg
CLK1 is a dual specificity kinase that phosphorylates PTP-1B and members of the SR family of splicing factors. It is thought to be involved in neuronal differentiation and mRNA splicing.
Catalog: PV3984
Size: 1 mg
Size: 1 mg
CLK3 is a dual specificity kinase that can interact with and cause the nuclear redistribution of SR proteins.
Catalog: PV3985
Size: 1 mg
Size: 1 mg
CLK4 belongs to the CDC2-like protein kinase (CLK) family. It can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus is thought to be involved in the regulation of alternative splicing.
Catalog: PV3986
Size: 1 mg
Size: 1 mg
CSNK1D (CK1 delta), a serine/threonine kinase, plays a critical role in Wnt/beta-catenin signaling pathway. This pathway is important in both development and cancer.
Catalog: PV3987
Size: 1 mg
Size: 1 mg
CSNK1E (CK1 epsilon) is a serine⁄threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis.
Catalog: PV3988
Size: 1 mg
Size: 1 mg
CSNK1G1 (CK1 gamma 1) is one of the most abundant serine⁄threonine kinases in eukaryotic cell extracts. Multiple isoforms of the enzyme exist, and the gamma-1 isoform is involved in growth and morphogenesis of eukaryotic cells.
Catalog: PV3989
Size: 1 mg
Size: 1 mg
CSNK1G2 (CK1 gamma 2) is a serine⁄threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis.
Catalog: PV3990
Size: 1 mg
Size: 1 mg
The casein kinase I (CKI) gene family encodes serine⁄threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric and range from 25 to 55 kD. They are ubiquitous, being found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells
Catalog: PV3991
Size: 1 mg
Size: 1 mg
CSNK2A1 is a serine⁄threonine protein kinase that phosphorylates acidic proteins.
Catalog: PV3992
Size: 1 mg
Size: 1 mg
Casein kinase II is a protein serine⁄threonine kinase that is thought to be present in all eukarotic cells, implying that it has fundamental cellular functions. The holoenzyme is a tetramer containing 2 alpha or alpha-prime subunits (or one of each) and 2 beta subunits. The function of beta subunits is unknown and the alpha subunit is the catalytic unit.
Catalog: PV3993
Size: 1 mg
Size: 1 mg
DAPK2 is a calcium⁄calmodulin-dependent kinase that acts as a positive regulator of apoptosis, and is expressed in many tissue types.
Catalog: PV3994
Size: 1 mg
Size: 1 mg
DAPK3 is a serine⁄threonine kinase which is functionally linked to cell motility, smooth muscle contractility and cell death processes.
Catalog: PV3995
Size: 1 mg
Size: 1 mg
DMPK is a serine⁄threonine kinase expressed in various muscle and nerve tissues. Mutations in the untranslated region of the DMPK gene are a characteristic of myotonic dystrophy.
Catalog: PV3996
Size: 1 mg
Size: 1 mg
DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21, and has been implicated in the pathogenesis of this disease.
Catalog: PV3997
Size: 1 mg
Size: 1 mg
DYRK3 belongs to the DYRK family of dual-specificity protein kinases that catalyze phosphorylation of serine⁄threonine and tyrosine residues. The members of this family share structural similarity, but differ in their substrate specificity, suggesting their involvement in different cellular functions.
Catalog: PV3998
Size: 1 mg
Size: 1 mg
Products from Prkci (Pkc Iota) Recombinant Human Protein to Dyrk3 Recombinant Human Protein
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