Products from Eif2ak1 (Hri) Human Protein to Igf1r Recombinant Human Protein
EIF2AK1 (HRI) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK1, signaling is initiated by low levels of heme.
Catalog: PR9072A
Size: 100 µg
Size: 100 µg
TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1.
Catalog: PR9075A
Size: 100 µg
Size: 100 µg
TXK, along with the close relatives BMS, ITK, and BTK, signal downstream of antigen receptors and other types of receptors.
Catalog: PR9089A
Size: 100 µg
Size: 100 µg
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Certain mutations (e.g. I2020T, G2019S, and R1441C) in this gene have been associated with Parkinson's disease. D1994A is an artificial mutation that renders the kinase catalytically inactive and thus serves as a useful control for activity assays, especially when testing novel substrates. Related Links: • LRRK2 tools for advancing Parkinson's disease research • Kinase protein portfolio • LanthaScreen® Eu Kinase Binding Assay • LanthaScreen® Activity Assay
Catalog: PR9102A
Size: 100 µg
Size: 100 µg
DNA-PK is a heterotrimeric, DNA-dependent protein kinase that initiates signalling cascades in response to DNA damage. DNA-PK is an atypical kinase, closely related to the PI3 kinases, and is often potently inhibited by small molecules designed to target PI3 kinases.
Catalog: PR9107A
Size: 100 µg
Size: 100 µg
This recombinant fusion protein consists of full-length activin A receptor kinase and a glutathione S-transferase (GST) tag. It is validated in the LanthaScreen® Eu Kinase Binding Assay. No special measures were taken to activate this kinase. • Compatible and validated with the LanthaScreen® Eu Kinase Binding Assay • Expressed in insect cells • GST tagged for use with Eu-labeled GST antibody Easily Screen for Kinase Binding The LanthaScreen® Eu Kinase Binding Assay is a TR-FRET assay that lets you measure inhibitor binding to non-activated kinases, perform simple off-rate measurements, and mak...
Catalog: PR9111A
Size: 100 µg
Size: 100 µg
BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrane ser⁄thr kinases which phosphorylates intracellular SMADs in response to bone morphogenic proteins.
Catalog: PR9136A
Size: 100 µg
Size: 100 µg
The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylating eIF4E on Ser209, and may contribute to tumorigenesis.
Catalog: PR9138A
Size: 100 µg
Size: 100 µg
ACVR2B is a type II member of the TGF-beta family of receptor ser⁄thr kinases and is involved in the activin and myostatin signaling pathway.
Catalog: PR9140B
Size: 100 µg
Size: 100 µg
This recombinant fusion protein consists of the catalytic domain of transforming growth factor beta receptor 2 (TGFBR2) and glutathione S-transferase (GST) tag. It is validated in the LanthaScreen® Eu Kinase Binding Assay. No special measures were taken to activate this kinase. • Compatible and validated with the LanthaScreen® Eu Kinase Binding Assay • Expressed in insect cells • GST tagged for use with Eu-labeled GST antibody Easily Screen for Kinase Binding The LanthaScreen® Eu Kinase Binding Assay is a TR-FRET assay that lets you measure inhibitor binding to non-activated kinases, perform s...
Catalog: PR9154A
Size: 100 µg
Size: 100 µg
This recombinant fusion protein consists of the catalytic domain of transforming growth factor beta receptor 2 (TGFBR2) and glutathione S-transferase (GST) tag. It is validated in the LanthaScreen® Eu Kinase Binding Assay. No special measures were taken to activate this kinase. • Compatible and validated with the LanthaScreen® Eu Kinase Binding Assay • Expressed in insect cells • GST tagged for use with Eu-labeled GST antibody Easily Screen for Kinase Binding The LanthaScreen® Eu Kinase Binding Assay is a TR-FRET assay that lets you measure inhibitor binding to non-activated kinases, perform s...
Catalog: PR9171A
Size: 100 µg
Size: 100 µg
This recombinant fusion protein consists of full-length glycogen synthase kinase 3 alpha (GSK3A) and a glutathione S-transferase (GST) tag. It is validated in the LanthaScreen® Eu Kinase Binding Assay. No special measures were taken to activate this kinase. • Compatible and validated with the LanthaScreen® Eu Kinase Binding Assay • Expressed in insect cells • GST tagged for use with Eu-labeled GST antibody Easily Screen for Kinase Binding The LanthaScreen® Eu Kinase Binding Assay is a TR-FRET assay that lets you measure inhibitor binding to non-activated kinases, perform simple off-rate measur...
Catalog: PR9188A
Size: 100 µg
Size: 100 µg
The Aurora kinases associate with microtubules during chromosome movement and segregation. AURKB (Aurora B) localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers.
Catalog: PR9210B
Size: 100 µg
Size: 100 µg
Two-well indirect ELISA kits enable sensitive and specific detection of pathogen-specific antibodies in animal samples, allowing for reliable and rapid screening and detection of seropositive animals. How the kit works: 1. Samples are added to the specific antigen-coated microplate. If present in the sample, specific anti-pathogen antibodies bind to the antigen and form antigen-antibody complexes. 2. After washing, an anti-species peroxidase-labeled conjugate is added, which binds to any antibodies attached to the plate. 3. After a second washing, a chromogenic substrate is added. Color develo...
Catalog: PRRSBI5
Size: 240 tests
Size: 240 tests
Real-time PCR enables sensitive and specific detection of pathogen nucleic acid in animal samples, allowing for reliable and rapid screening and detection of infected animals. The LSI™ VetMAX™ kits include: • 1 ready-to-use mix that includes a set of oligonucleotides for detection of the target gene OR these separate components that will need to be mixed together: a set of oligonucleotides for the detection of the target gene + a TaqMan® real-time PCR master mix + an RT enzyme (only for RNA kits) • 1 external positive control of the same nature as the target (inactivated bacteria or virus). Us...
Catalog: PRRSEUNA
Size: 100 tests
Size: 100 tests
Same as PRVGB2/I Single-well blocking ELISA kits enable sensitive and specific detection of pathogen-specific antibodies in animal samples, allowing for reliable and rapid screening and detection of seropositive animals. How the kit works: 1. Samples are added to the specific antigen-coated microplate. If present in the sample, specific anti-pathogen antibodies bind to the antigen and form antigen-antibody complexes. 2 . After washing, an anti-pathogen peroxidase-labeled conjugate is added, which binds to any remaining unbound antigen. 3 . After a second washing, a chromogenic substrate is add...
Catalog: PRVGB2I
Size: 192 tests
Size: 192 tests
Same as PRVGB5/I Single-well blocking ELISA kits enable sensitive and specific detection of pathogen-specific antibodies in animal samples, allowing for reliable and rapid screening and detection of seropositive animals. How the kit works: 1. Samples are added to the specific antigen-coated microplate. If present in the sample, specific anti-pathogen antibodies bind to the antigen and form antigen-antibody complexes. 2 . After washing, an anti-pathogen peroxidase-labeled conjugate is added, which binds to any remaining unbound antigen. 3 . After a second washing, a chromogenic substrate is add...
Catalog: PRVGB5I
Size: 480 tests
Size: 480 tests
Same as PRVGE2/I Single-well blocking ELISA kits enable sensitive and specific detection of pathogen-specific antibodies in animal samples, allowing for reliable and rapid screening and detection of seropositive animals. How the kit works: 1. Samples are added to the specific antigen-coated microplate. If present in the sample, specific anti-pathogen antibodies bind to the antigen and form antigen-antibody complexes. 2 . After washing, an anti-pathogen peroxidase-labeled conjugate is added, which binds to any remaining unbound antigen. 3 . After a second washing, a chromogenic substrate is add...
Catalog: PRVGE2I
Size: 192 tests
Size: 192 tests
Same as PRVGE5/I Single-well blocking ELISA kits enable sensitive and specific detection of pathogen-specific antibodies in animal samples, allowing for reliable and rapid screening and detection of seropositive animals. How the kit works: 1. Samples are added to the specific antigen-coated microplate. If present in the sample, specific anti-pathogen antibodies bind to the antigen and form antigen-antibody complexes. 2 . After washing, an anti-pathogen peroxidase-labeled conjugate is added, which binds to any remaining unbound antigen. 3 . After a second washing, a chromogenic substrate is add...
Catalog: PRVGE5I
Size: 480 tests
Size: 480 tests
Single-well Indirect ELISA kits enable sensitive and specific detection of pathogen-specific antibodies in animal samples, allowing for reliable and rapid screening and detection of seropositive animals. How the kit works: 1. Samples are added to the specific antigen-coated microplate. If present in the sample, specific anti-pathogen antibodies bind to the antigen and form antigen-antibody complexes. 2. After washing, an anti-species peroxidase-labeled conjugate is added, which binds to any antibodies attached to the plate. 3. After a second washing, a chromogenic substrate is added. Color dev...
Catalog: PTML5
Size: 480 tests
Size: 480 tests
ATP is an essential component for kinase assays using LanthaScreen™ Technology. Invitrogen's ATP is 10mM in water.
Catalog: PV3227
Size: 500 µl
Size: 500 µl
SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth.
Catalog: PV3584
Size: 1 mg
Size: 1 mg
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response.
Catalog: PV3585
Size: 1 mg
Size: 1 mg
ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and⁄or cytoskeletal reorganization.
Catalog: PV3586
Size: 1 mg
Size: 1 mg
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders.
Catalog: PV3587
Size: 1 mg
Size: 1 mg
MET (cMET) is a receptor-like tyrosine kinase whose disregulation has been linked to many types of human malignancies.
Catalog: PV3588
Size: 1 mg
Size: 1 mg
KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis.
Catalog: PV3589
Size: 1 mg
Size: 1 mg
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.
Catalog: PV3590
Size: 1 mg
Size: 1 mg
PDGFRB is a receptor tyrosine kinase and has been implicated in atherogenesis and in cell transformation by the SIS oncogene.
Catalog: PV3591
Size: 1 mg
Size: 1 mg
IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2. IGFR has been implicated in a variety of cancers.
Catalog: PV3592
Size: 1 mg
Size: 1 mg
Products from Eif2ak1 (Hri) Human Protein to Igf1r Recombinant Human Protein
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