Products from Ripk2 Recombinant Human Protein to Fgfr3 [K650e] Recombinant Human Protein

RIPK2 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

RIPK2 is a serine⁄threonine kinase that is involved in cell activation, proliferation, differentiation, and apoptosis.
Catalog: PR7829A
Size: 100 µg

LIMK1 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

LIMK1 is a serine⁄threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK1 has also been implicated in brain development.
Catalog: PR7844A
Size: 100 µg

SRPK1 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

SRPK1 is a serine⁄threonine kinase that plays a role in the regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors.
Catalog: PR7847A
Size: 100 µg

DCAMKL2 (DCK2) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

DCAMKL2 is a serine⁄threonine kinase involved in signal transduction and cellular communication, and is the human homolog of a rat protein kinase expressed in cerebrocortical lamination that binds microtubules.
Catalog: PR7853A
Size: 100 µg

PAK4 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

PAK4 is a serine⁄ threonine p21 activating kinase implicated in the reorganization of actin cytoskeleton and in the formation of filopodia.
Catalog: PR7856A
Size: 100 µg

STK16 (PKL12) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

STK16 (PKL12) is a serine⁄threonine kinase that functions in signal transduction pathways and transcriptional regulation.
Catalog: PR7859A
Size: 100 µg

MAP3K8 (COT) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MAP3K8 (COT) is a serine⁄threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle.
Catalog: PR7887A
Size: 100 µg

MST1R (RON) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

MST1R (RON) is a receptor tyrosine kinase involved in cell proliferation and motility.
Catalog: PR7906A
Size: 100 µg

ACVR1B (ALK4) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

ACVR1B is a serine⁄threonine kinase involved in signal transduction and cellular communication. Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors. Mutations of ACVR1B have been observed in pancreatic adenocarcinomas.
Catalog: PR7950A
Size: 100 µg

STK33 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

STK33 is a serine⁄threonine kinase involved in signal transduction and cellular communication.
Catalog: PR7986A
Size: 100 µg

WNK3 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

WNK3 is a serine⁄threonine kinase involved in signal transduction and cellular communication
Catalog: PR7989A
Size: 100 µg

MAP3K7⁄MAP3K7IP1 (TAK1-TAB1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MAP3K7 (TAK1) controls transcription regulation and apoptosis, and is implicated in inflammatory disease and rheumatoid arthritis. Fusion of MAP3K7 to MAP3K7IP1 (TAB1) activates MAP3K7.
Catalog: PR8004B
Size: 100 µg

CAMK1 (CaMK1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CAMK1 (CaMK1) is a serine⁄threonine kinase that is a member of the calcium⁄calmodulin-dependent protein kinase family. It is involved in cell differentiation, nervous system development, and signal transduction.
Catalog: PR8013A
Size: 100 µg

MYLK (MLCK) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MYLK (MLCK) is a serine⁄threonine kinase that phosphorylates myosin regulatory light chains to assist in the production of contractile activity (myosin-actin interaction).
Catalog: PR8016A
Size: 100 µg

WNK2 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

WNK2 is a serine⁄threonine kinase involved in signal transduction and cellular communication
Catalog: PR8019A
Size: 100 µg

PRKG1 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

PRKG1 is a cGMP-dependent serine⁄threonine kinase which has an important role in the relaxation of vascular smooth muscle and the inhibition of platelet aggregation
Catalog: PR8028A
Size: 100 µg

IKBKE (IKK Epsilon) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

IKBKE is an activator of nuclear factor-kappa-B. Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death.
Catalog: PR8031B
Size: 100 µg

MARK1 (MARK) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MARK1 (MARK) is a serine⁄threonine kinase which is involved in cytoskeletal organization and biogenesis
Catalog: PR8034A
Size: 100 µg

BRSK1 (SAD1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

BRSK1 (SAD1) is a serine⁄threonine kinase, and is a UV-induced DNA damage checkpoint kinase
Catalog: PR8037A
Size: 100 µg

MKNK2 (MNK2) Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylation eIF4E on Ser209, and may contribute to tumorigenesis.
Catalog: PR8046A
Size: 100 µg

EGFR (ErbB1) [T790M] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The T790M mutant of EGFR has arisen in the clinics and displays resistance to Erlotinib (Tarceva) and Gefitinib (Iressa).
Catalog: PR8052A
Size: 100 µg

CDK4⁄Cyclin D1 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CDK4 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with CyclinD1.
Catalog: PR8064A
Size: 100 µg

CDC42 BPA (MRCKA) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CDC42BPA (MRCKA) is a serine⁄threonine kinase which functions in actin cytoskeleton assembly and organization.
Catalog: PR8067A
Size: 100 µg

CDC42BPB (MRCKB) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CDC42BPB is a serine⁄threonine kinases which functions in actin cytoskeleton assembly and organization.
Catalog: PR8070A
Size: 100 µg

JAK2 Recombinant Human Protein, JH1 and JH2 Domains

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2.
Catalog: PR8078A
Size: 100 µg

LTK (TYK1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

LTK (TYK1) is a member of the ros⁄insulin receptor family of kinases involved in cell growth and differentiation.
Catalog: PR8108A
Size: 100 µg

JAK2 [V617F] Recombinant Human Protein, JH1 and JH2 Domains

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera.
Catalog: PR8134A
Size: 100 µg

IRAK1 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

IL-1 receptor associated kinases (IRAKs) are serine⁄threonine kinases involved in signaling via Toll⁄IL-1 pathways.
Catalog: PR8140B
Size: 100 µg

PAK7 (KIAA1264) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

PAK7 (KIAA1264) is implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling.
Catalog: PR8143A
Size: 100 µg

FGFR3 [K650E] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. The K650E mutation leads to constitutive activation and the neonatal lethal disorder TDII.
Catalog: PR8155A
Size: 100 µg