Products from Plk2 Recombinant Human Protein to Ikbke (Ikk Epsilon) Recombinant Human Protein
PLK2 is a serum inducible serine⁄threonine kinase that is a member of the polo family of serine⁄threonine kinases which have a role in normal cell division. The kinase may play a role in embryogenesis, wound healing, and neoplasia.
Catalog: PR7592A
Size: 100 µg
Size: 100 µg
CHUK (IKK alpha) is a serine⁄threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an inhibitor of the NF-kappa B complex.
Catalog: PR7619B
Size: 100 µg
Size: 100 µg
HIPK3 is a serine⁄threonine kinase involved in signal transduction, cellular communication, and multidrug resistance of tumors and plays a role in the phosphorylation of FADD.
Catalog: PR7715A
Size: 100 µg
Size: 100 µg
FRK (PTK5) is a nuclear protein and may function during G1 and S phase of the cell cycle, suppressing growth.
Catalog: PR7729A
Size: 100 µg
Size: 100 µg
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. The PDGFRA V561D mutation is observed in gastrointestinal stromal tumors (GIST).
Catalog: PR7732A
Size: 100 µg
Size: 100 µg
KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. The clinically observed V654A mutant has been demonstrated to be resistant to inhibition with imatinib.
Catalog: PR7738A
Size: 100 µg
Size: 100 µg
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA D842V is expressed in a high percentage of epithelial ovarian cancers and is implicated in the pathogenesis of acute myelogenous leukemia.
Catalog: PR7741A
Size: 100 µg
Size: 100 µg
CLK2 is a serine⁄threonine kinase that phosphorylates serine⁄arginine-rich proteins as related to controlling RNA splicing. It is also thought to link cell cycle progression, apoptosis, and telomere length regulation.
Catalog: PR7747B
Size: 100 µg
Size: 100 µg
PHKG2 is a testis⁄liver isoform of the phosphorylase kinase gamma subunit.
Catalog: PR7753A
Size: 100 µg
Size: 100 µg
CAMK2B (CaMKII beta) is a serine⁄threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization and regulation of gene expression. As a dominant kinase in the central nervous system it may function in long term potentiation and neurotransmitter release.
Catalog: PR7771A
Size: 100 µg
Size: 100 µg
CAMKK2 (CaMKK beta) is a serine⁄threonine kinase involved in neurogenesis, cell differentiation, and signal transduction. It also activates CAMKI and CAMKIV, and plays a role in the development of long term memory.
Catalog: PR7777A
Size: 100 µg
Size: 100 µg
MAP4K2 (GCK) is a serine⁄ threonine protein kinase that activates the JNK pathway. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of the germinal center, where it may participate in B-cell differentiation. The kinase may also play a role in the regulation of vesicle targeting or fusion.
Catalog: PR7802A
Size: 100 µg
Size: 100 µg
Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains the catalytic domain (JH1) of JAK2.
Catalog: PR7820B
Size: 100 µg
Size: 100 µg
RIPK2 is a serine⁄threonine kinase that is involved in cell activation, proliferation, differentiation, and apoptosis.
Catalog: PR7829A
Size: 100 µg
Size: 100 µg
LIMK1 is a serine⁄threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK1 has also been implicated in brain development.
Catalog: PR7844A
Size: 100 µg
Size: 100 µg
SRPK1 is a serine⁄threonine kinase that plays a role in the regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors.
Catalog: PR7847A
Size: 100 µg
Size: 100 µg
DCAMKL2 is a serine⁄threonine kinase involved in signal transduction and cellular communication, and is the human homolog of a rat protein kinase expressed in cerebrocortical lamination that binds microtubules.
Catalog: PR7853A
Size: 100 µg
Size: 100 µg
PAK4 is a serine⁄ threonine p21 activating kinase implicated in the reorganization of actin cytoskeleton and in the formation of filopodia.
Catalog: PR7856A
Size: 100 µg
Size: 100 µg
STK16 (PKL12) is a serine⁄threonine kinase that functions in signal transduction pathways and transcriptional regulation.
Catalog: PR7859A
Size: 100 µg
Size: 100 µg
MAP3K8 (COT) is a serine⁄threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle.
Catalog: PR7887A
Size: 100 µg
Size: 100 µg
MST1R (RON) is a receptor tyrosine kinase involved in cell proliferation and motility.
Catalog: PR7906A
Size: 100 µg
Size: 100 µg
ACVR1B is a serine⁄threonine kinase involved in signal transduction and cellular communication. Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors. Mutations of ACVR1B have been observed in pancreatic adenocarcinomas.
Catalog: PR7950A
Size: 100 µg
Size: 100 µg
STK33 is a serine⁄threonine kinase involved in signal transduction and cellular communication.
Catalog: PR7986A
Size: 100 µg
Size: 100 µg
WNK3 is a serine⁄threonine kinase involved in signal transduction and cellular communication
Catalog: PR7989A
Size: 100 µg
Size: 100 µg
MAP3K7 (TAK1) controls transcription regulation and apoptosis, and is implicated in inflammatory disease and rheumatoid arthritis. Fusion of MAP3K7 to MAP3K7IP1 (TAB1) activates MAP3K7.
Catalog: PR8004B
Size: 100 µg
Size: 100 µg
CAMK1 (CaMK1) is a serine⁄threonine kinase that is a member of the calcium⁄calmodulin-dependent protein kinase family. It is involved in cell differentiation, nervous system development, and signal transduction.
Catalog: PR8013A
Size: 100 µg
Size: 100 µg
MYLK (MLCK) is a serine⁄threonine kinase that phosphorylates myosin regulatory light chains to assist in the production of contractile activity (myosin-actin interaction).
Catalog: PR8016A
Size: 100 µg
Size: 100 µg
WNK2 is a serine⁄threonine kinase involved in signal transduction and cellular communication
Catalog: PR8019A
Size: 100 µg
Size: 100 µg
PRKG1 is a cGMP-dependent serine⁄threonine kinase which has an important role in the relaxation of vascular smooth muscle and the inhibition of platelet aggregation
Catalog: PR8028A
Size: 100 µg
Size: 100 µg
IKBKE is an activator of nuclear factor-kappa-B. Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death.
Catalog: PR8031B
Size: 100 µg
Size: 100 µg
Products from Plk2 Recombinant Human Protein to Ikbke (Ikk Epsilon) Recombinant Human Protein
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