Products from Kit [T670i] Recombinant Human Protein to Prkg2 (Pkg2) Recombinant Human Protein
KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. KIT T670I is a Gleevec resistant form of KIT.
Catalog: PR7423A
Size: 100 µg
Size: 100 µg
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The G250E mutant is a Gleevec resistant form of ABL1.
Catalog: PR7426A
Size: 100 µg
Size: 100 µg
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The T315I mutant is a Gleevec resistant form of ABL1.
Catalog: PR7429B
Size: 100 µg
Size: 100 µg
MET (cMET) is a receptor-like tyrosine kinase whose disregulation has been linked to many types of human malignancies. The M1250T mutant of MET is both activating and displays altered substrate specificity.
Catalog: PR7432A
Size: 100 µg
Size: 100 µg
The epidermal growth factor receptor is a receptor tyrosine kinase that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L861Q mutation is an Iressa-responsive mutant observed in the clinic.
Catalog: PR7435A
Size: 100 µg
Size: 100 µg
MUSK plays an important and selective role in many aspects of skeletal muscle development and function through the initial step of postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn.
Catalog: PR7438A
Size: 100 µg
Size: 100 µg
NEK7 belongs to the NIMA family of kinases which are involved in DNA replication and genotoxic stress response.
Catalog: PR7441A
Size: 100 µg
Size: 100 µg
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The Y253F mutant is a Gleevec resistant form of ABL1.
Catalog: PR7444A
Size: 100 µg
Size: 100 µg
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L858R mutation is implicated in epithelial tumor formation.
Catalog: PR7447A
Size: 100 µg
Size: 100 µg
FLT3 is a tyrosine protein kinase that is a member of the growth factor receptor tyrosine kinase family. The FLT3 D835Y mutant is a drug resistant form of FLT3.
Catalog: PR7450A
Size: 100 µg
Size: 100 µg
CLK4 belongs to the CDC2-like protein kinase (CLK) family. It can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus is thought to be involved in the regulation of alternative splicing.
Catalog: PR7453A
Size: 100 µg
Size: 100 µg
EPHA5 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system.
Catalog: PR7459A
Size: 100 µg
Size: 100 µg
SRPK2, along with SRPK1, is most likely the cellular protein kinase mediating HBV core protein phosphorylation during viral infection. It therefore represents an important host cell target for therapeutic intervention in HBV infection.
Catalog: PR7462A
Size: 100 µg
Size: 100 µg
SLK acts as a novel effector of cytoskeletal remodeling and apoptosis, and seems to be ubiquitously expressed.
Catalog: PR7465A
Size: 100 µg
Size: 100 µg
RPS6KB2 (p70S6K beta) is a serine⁄threonine kinase with 2 non-identical kinase catalytic domains which phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Catalog: PR7468B
Size: 100 µg
Size: 100 µg
The casein kinase I (CKI) gene family encodes serine⁄threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric and range from 25 to 55 kD. They are ubiquitous, being found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells
Catalog: PR7474A
Size: 100 µg
Size: 100 µg
TYRO3 is a receptor tyrosine kinase that has been shown to be involved in signal transduction and cell adhesion.
Catalog: PR7480A
Size: 100 µg
Size: 100 µg
Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex.
Catalog: PR7489A
Size: 1 mg
Size: 1 mg
Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex.
Catalog: PR7489B
Size: 100 µg
Size: 100 µg
DYRK3 belongs to the DYRK family of dual-specificity protein kinases that catalyze phosphorylation of serine⁄threonine and tyrosine residues. The members of this family share structural similarity, but differ in their substrate specificity, suggesting their involvement in different cellular functions.
Catalog: PR7492A
Size: 100 µg
Size: 100 µg
PTK2 (FAK) is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents.
Catalog: PR7495A
Size: 100 µg
Size: 100 µg
EPHA1 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system.
Catalog: PR7498A
Size: 100 µg
Size: 100 µg
Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family. JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors.
Catalog: PR7507B
Size: 100 µg
Size: 100 µg
CDK9 is a serine⁄threonine kinase that phosphorylates the c-terminal domain of the largest subunit of RNA polymerase II and is involved in cell cycle regulation, This protein is coexpressed and copurified with CyclinK.
Catalog: PR7510A
Size: 100 µg
Size: 100 µg
ROR2 (receptor tyrosine kinase-like orphan receptor 2) is a type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. It is throught to be involved in the early formation of the chondrocytes and cartilage and growth plate development.
Catalog: PR7516A
Size: 100 µg
Size: 100 µg
LIMK2 is a serine⁄threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK2 has also been implicated in brain development.
Catalog: PR7519B
Size: 100 µg
Size: 100 µg
NLK is a serine⁄threonine kinase involved in signal transduction and cellular communication.
Catalog: PR7525A
Size: 100 µg
Size: 100 µg
CDK9 is a serine⁄threonine kinase which when complexed with CyclinT1 forms an active holoenzyme complex. This complex plays a key role in regulating the eukaryotic cell cycle. CDK9 is coexpressed and copurified with CyclinT1.
Catalog: PR7541B
Size: 100 µg
Size: 100 µg
NUAK1 (ARK5) is a serine⁄threonine kinase that plays a role in many cellular functions. The overexpression of this kinase has been associated with tumor invasion and metastasis (colorectal neoplasm).
Catalog: PR7569A
Size: 100 µg
Size: 100 µg
PRKG2 (PKG2) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity.
Catalog: PR7572A
Size: 100 µg
Size: 100 µg
Products from Kit [T670i] Recombinant Human Protein to Prkg2 (Pkg2) Recombinant Human Protein
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