Products from Ttk Recombinant Human Protein to Abl1 [E255k] Recombinant Human Protein

TTK Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

TTK is a serine⁄threonine kinase closely related to SPK1, PIM 1 and CDC2 serine⁄threonine kinases. TTK is a dual-specificity kinase, which can also phosphorylate tyrosine.
Catalog: PR7264B
Size: 100 µg

INSRR (IRR) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

INSRR, insulin receptor-related receptor, is a member of the insulin receptor (IR) family. INSRR does not bind insulin-like molecules, but is similar to INSR in tyrosine kinase activity.
Catalog: PR7286A
Size: 100 µg

ROS1 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

ROS1 is a tyrosine kinase that functions as a growth or differentiation factor receptor.
Catalog: PR7292A
Size: 100 µg

EGFR (ErbB1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics.
Catalog: PR7295B
Size: 100 µg

EPHA8 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

EPHA8 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA8 plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
Catalog: PR7298B
Size: 100 µg

SGKL (SGK3) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

SGKL (SGK3) is a serine⁄threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGKL is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK.
Catalog: PR7301A
Size: 100 µg

BRAF [V599E] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of cancers.
Catalog: PR7304A
Size: 100 µg

RAF1 (cRAF) [Y340D] [Y341D] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

RAF1 (cRAF) is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated RAF1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylates and activates the serine⁄threonine specific protein kinases ERK1 and ERK2. The RAF1 Y340D Y341D mutant is constitutively active.
Catalog: PR7307A
Size: 100 µg

RPS6KB1 (p70S6K) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

RPS6KB1 (p70S6K) is a serine⁄threonine kinase with 2 non-identical kinase catalytic domains which phosphorylates several residues of the S6 ribosomal protein.
Catalog: PR7310B
Size: 100 µg

SGK2 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

SGK2 is a serine⁄threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGK2 is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK.
Catalog: PR7313A
Size: 100 µg

PLK3 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

PLK3 is a member of the polo family of serine⁄threonine kinases. PLK3 is involved in the regulation of M phase in the cell cycle.
Catalog: PR7316B
Size: 100 µg

PHKG1 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

PHKG1 is a serine⁄threonine kinase with glycogenolytic regulatory functions.
Catalog: PR7319A
Size: 100 µg

STK4 (MST1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

STK4 (MST1) is a serine⁄threonine kinase which may be involved in apoptosis. It is possible that this protein induces the chromatin condensation observed in this process.
Catalog: PR7322A
Size: 100 µg

HIPK4 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

HIPK4 is a homeodomain-interacting protein kinase and has been demonstrated to phosphorylate p53.
Catalog: PR7340A
Size: 100 µg

FER Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

FER is a member of the FPS⁄FES family of non-receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
Catalog: PR7343A
Size: 100 µg

PDGFRA (PDGFR α) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family.
Catalog: PR7346A
Size: 100 µg

MAP3K5 (ASK1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MAP3K5 (ASK1) is a serine⁄threonine kinase that is abundantly expressed in human heart and pancreas.
Catalog: PR7349B
Size: 100 µg

MAP3K3 (MEKK3) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MAP3K3 (MEKK3) directly regulates MAPK8 and extracellular signal-regulated protein kinase (ERK) pathways by phosphorylating multiple MAP2Ks.
Catalog: PR7352A
Size: 100 µg

RET Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement.
Catalog: PR7355A
Size: 100 µg

SGK (SGK1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

SGK (SGK1) is a serine⁄threonine kinase that may be a transcriptional target for p38⁄MAPK in hepatoma cells.
Catalog: PR7358A
Size: 100 µg

CSNK1A1 (CK1 α 1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, which encodes serine⁄threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric, ranging from 25 to 55 kD, and are found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells.
Catalog: PR7361B
Size: 100 µg

CLK3 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CLK3 is a dual specificity kinase that can interact with and cause the nuclear redistribution of SR proteins.
Catalog: PR7367A
Size: 100 µg

PKN2 (PRK2) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

PKN2 (PRK2), a close relative of the PKCs, is a regulator of mitosis and exit from cytokinesis.
Catalog: PR7370A
Size: 100 µg

WEE1 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

WEE1, which is classified as a Ser⁄Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation.
Catalog: PR7373A
Size: 100 µg

PDGFRA [T674I] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. PDGFRA T674I is a Gleevec resistant form of PDGFRA.
Catalog: PR7385B
Size: 100 µg

CSNK1G1 (CK1 γ 1) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CSNK1G1 (CK1 gamma 1) is one of the most abundant serine⁄threonine kinases in eukaryotic cell extracts. Multiple isoforms of the enzyme exist, and the gamma-1 isoform is involved in growth and morphogenesis of eukaryotic cells.
Catalog: PR7391A
Size: 100 µg

Recombinant Human ProteinPAK1

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

PAK1 is a serine⁄threonine kinase that is a target for restenosis, cancer, and immunosuppression treatment.
Catalog: PR7402A
Size: 100 µg

MARK2 Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MARK2 is a serine⁄threonine protein kinase involved in the control of cell polarity and microtubule stability.
Catalog: PR7405A
Size: 100 µg

MAP3K2 (MEKK2) Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MAP3K2 (MEKK2) is a serine⁄threonine kinase that activates kinases involved in the MAP kinase signaling pathway.
Catalog: PR7408A
Size: 100 µg

ABL1 [E255K] Recombinant Human Protein

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The E255K mutant is a Gleevec resistant form of ABL1.
Catalog: PR7420A
Size: 100 µg