Products from Chek2 (Chk2) Recombinant Human Protein to Blk Recombinant Human Protein
CHEK2 (CHK2) is a serine⁄threonine kinase and a component of the DNA damage checkpoint pathway. A mutation in this gene has been linked to cancer. CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins.
Catalog: PR5460B
Size: 100 µg
Size: 100 µg
CSNK1G2 (CK1 gamma 2) is a serine⁄threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis.
Catalog: PR5511A
Size: 100 µg
Size: 100 µg
IL-1 receptor associated kinases (IRAKs) are serine⁄threonine kinases involved in signaling via Toll⁄IL-1 pathways.
Catalog: PR5612U
Size: 100 µg
Size: 100 µg
TBK1 is similar to the IKB kinases and is involved with NF-kappa B activation. In addition, TBK1, along with IKK epsilon, is involved with IRF3 signaling.
Catalog: PR5618B
Size: 100 µg
Size: 100 µg
DAPK2 is a calcium⁄calmodulin-dependent kinase that acts as a positive regulator of apoptosis, and is expressed in many tissue types.
Catalog: PR5688A
Size: 100 µg
Size: 100 µg
RPS6KA2 (RSK3) is a serine-threonine kinase that is part of the ribosomal S6 kinase family and the subfamily of insulin⁄mitogen-stimulated kinases. It is thought that RPS6KA2 is a signal-transducing intermediate in the cellular response to several growth factors. It is found in many tissues, but in higher levels in lung and skeletal muscle.
Catalog: PR5813A
Size: 100 µg
Size: 100 µg
AURKA (Aurora A) is a serine⁄threonine kinase that regulates mitosis by association in vivo with centrosomes. Overexpression of AURKA is observed in many types of cancer.
Catalog: PR5935A
Size: 100 µg
Size: 100 µg
STK22B (TSSK2) is a serine⁄threonine kinase essential for the function and production of sperm (spermiogenesis). Deletions in the STK22B coding region correlate with numerous cardiovascular and glandular malformations.
Catalog: PR5947A
Size: 100 µg
Size: 100 µg
Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6, and is involved in the stimulation of cell proliferation.
Catalog: PR5983B
Size: 100 µg
Size: 100 µg
KDR (VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors.
Catalog: PR5992A
Size: 1 mg
Size: 1 mg
KDR (VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors.
Catalog: PR5992C
Size: 100 µg
Size: 100 µg
NTRK2 (TRKB) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. NTRK2 is the receptor for brain-derived neurotrophic factor (BDNF). Together, NTRK2 and BDNF regulate both short-term synaptic functions and long-term potentiation of brain synapses.
Catalog: PR5995A
Size: 1 mg
Size: 1 mg
NTRK2 (TRKB) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. NTRK2 is the receptor for brain-derived neurotrophic factor (BDNF). Together, NTRK2 and BDNF regulate both short-term synaptic functions and long-term potentiation of brain synapses.
Catalog: PR5995D
Size: 100 µg
Size: 100 µg
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system.
Catalog: PR5998B
Size: 100 µg
Size: 100 µg
Casein kinase II is a protein serine⁄threonine kinase that is thought to be present in all eukarotic cells, implying that it has fundamental cellular functions. The holoenzyme is a tetramer containing 2 alpha or alpha-prime subunits (or one of each) and 2 beta subunits. The function of beta subunits is unknown and the alpha subunit is the catalytic unit.
Catalog: PR6299B
Size: 100 µg
Size: 100 µg
GRK6 is a member of the guanine nucleotide-binding protein coupled receptor kinase subfamily of the serine⁄threonine protein kinase family. GRK6 phosphorylates the activated forms of G protein-coupled receptors to initiate their deactivation.
Catalog: PR6302C
Size: 100 µg
Size: 100 µg
Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3. ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.
Catalog: PR6308B
Size: 100 µg
Size: 100 µg
EPHB1 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation.
Catalog: PR6311B
Size: 100 µg
Size: 100 µg
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells. TEK signaling appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, and defects in TEK are associated with inherited venous malformations.
Catalog: PR6314A
Size: 100 µg
Size: 100 µg
MERTK (cMER) is a tyrosine kinase proto-oncogene and is involved in the retinal pigment epithelium (RPE) phagocytosis pathway, which is implicated in human retinal disease.
Catalog: PR6317A
Size: 100 µg
Size: 100 µg
EPHB2 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation.
Catalog: PR6320A
Size: 100 µg
Size: 100 µg
DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumour suppressor.
Catalog: PR6332A
Size: 100 µg
Size: 100 µg
PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function.
Catalog: PR6347B
Size: 100 µg
Size: 100 µg
STK24 (MST3) is a serine⁄threonine kinase that is a member of the GCK subfamily of STE20-like proteins.
Catalog: PR6359A
Size: 100 µg
Size: 100 µg
MAP2K3 (MEK3) is a dual-specificity protein kinase which acts in cellular signal transduction pathways, and is necessary for the expression of glucose transporter.
Catalog: PR6413A
Size: 100 µg
Size: 100 µg
EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system.
Catalog: PR6419A
Size: 100 µg
Size: 100 µg
AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome⁄spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction.
Catalog: PR6425A
Size: 100 µg
Size: 100 µg
TAOK3 (JIK) is a serine⁄threonine kinase that is a member of the GCK-like subfamily of the STE20 kinase family. JIK is ubiquitously expressed in human tissues, inhibits JNK and has been implicated in cancer.
Catalog: PR6434A
Size: 100 µg
Size: 100 µg
MAPK9 (JNK2) is a serine⁄threonine kinase which plays an important role in the MAPK pathway.
Catalog: PR6568B
Size: 100 µg
Size: 100 µg
B-lymphoid tyrosine kinase (BLK) is a non-receptor tyrosine kinase that belongs to the Src family of kinases. BLK plays an important role in B-cell activation.
Catalog: PR6635A
Size: 100 µg
Size: 100 µg
Products from Chek2 (Chk2) Recombinant Human Protein to Blk Recombinant Human Protein
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