Products from Cdk1⁄Cyclin B Recombinant Human Protein to Camk2d (Camkii Delta) Recombinant Human Protein
CDK1 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF). It is essential for G1⁄S and G2⁄M phase transitions of the eukaryotic cell cycle, and plays important regulatory roles in cell cycle control. This protein is coexpressed and copurified with CyclinB.
Catalog: PR4768C
Size: 100 µg
Size: 100 µg
ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and⁄or cytoskeletal reorganization.
Catalog: PR4795A
Size: 100 µg
Size: 100 µg
TEC is a non-receptor protein-tyrosine kinase containing a pleckstrin homology domain and is highly expressed in many hematopoietic cell lines.
Catalog: PR4801B
Size: 100 µg
Size: 100 µg
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.
Catalog: PR4918A
Size: 100 µg
Size: 100 µg
MAP2K1 (MEK1) kinse is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx.
Catalog: PR5043A
Size: 100 µg
Size: 100 µg
MATK (Hyl) is a non-receptor CSK-type protein tyrosine kinase that is thought to function in signal transduction pathways important in megakaryocyte growth and⁄or differentiation.
Catalog: PR5045A
Size: 100 µg
Size: 100 µg
MAPK14 (p38 alpha) is a member of the stress-activated protein kinase class of MAPKs.
Catalog: PR5049C
Size: 100 µg
Size: 100 µg
FES (FPS) is a tyrosine protein kinase that is required for maintenance of cellular transformation. Its chromosomal location is linked to a specific translocation event identified in patients with acute promyelocytic leukemia, and it is also involved in normal hematopoiesis.
Catalog: PR5068B
Size: 100 µg
Size: 100 µg
GSK3B is a proline-directed serine⁄threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation.
Catalog: PR5074A
Size: 100 µg
Size: 100 µg
Bone marrow tyrosine kinase (BMX) is a non-receptor tyrosine kinase that belongs to the SRC-related TEC subfamily of tyrosine kinases. It is an important regulator of various cellular processes including apoptosis, cell survival, cellular differentiation, cell migration, and transformation.
Catalog: PR5116C
Size: 100 µg
Size: 100 µg
PBK (TOPK) is a serine⁄threonine kinase that is related to the dual specific mitogen-activated protein kinase kinase (MAPKK). The kinase is up-regulated in a variety of hematological malignancies, participates in activating lymphoid cells, and supports testicular function (spermatogenesis).
Catalog: PR5143A
Size: 100 µg
Size: 100 µg
CSNK1E (CK1 epsilon) is a serine⁄threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis.
Catalog: PR5147A
Size: 100 µg
Size: 100 µg
STK22D (TSSK1) is a serine⁄threonine kinase essential to the function and production of sperm (spermiogenesis).
Catalog: PR5214A
Size: 100 µg
Size: 100 µg
NEK6 controls the initiation of mitosis and is required for the metaphase-anaphase transition.
Catalog: PR5235A
Size: 100 µg
Size: 100 µg
CAMK4 (CaMKIV) is a serine⁄threonine protein kinase that phosphoryates CREB, oncoprotein 18, and SRF. It has limited tissue distribution, and has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
Catalog: PR5249B
Size: 100 µg
Size: 100 µg
MAPK3 (ERK1) is a serine⁄threonine kinase that is an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.
Catalog: PR5254B
Size: 100 µg
Size: 100 µg
MAPK1 (ERK2) is a serine⁄threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.
Catalog: PR5257A
Size: 100 µg
Size: 100 µg
CLK1 is a dual specificity kinase that phosphorylates PTP-1B and members of the SR family of splicing factors. It is thought to be involved in neuronal differentiation and mRNA splicing.
Catalog: PR5259A
Size: 100 µg
Size: 100 µg
EPHA3 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA3 encodes a protein that binds ephrin-A ligands.
Catalog: PR5270A
Size: 100 µg
Size: 100 µg
The proto-oncogene PIM1 is upregulated in prostate cancer.
Catalog: PR5298A
Size: 1 mg
Size: 1 mg
The proto-oncogene PIM1 is upregulated in prostate cancer.
Catalog: PR5298C
Size: 100 µg
Size: 100 µg
PLK1 is a serine⁄threonine kinase that is thought to function in cell mitosis and regarded as a marker of cell proliferation. It has been found to play a critical role in carcinogenesis.
Catalog: PR5304B
Size: 100 µg
Size: 100 µg
PAK6 is a serine⁄threonine kinase expressed in the testis and prostate. It associates with both the estrogen and androgen receptors.
Catalog: PR5307A
Size: 100 µg
Size: 100 µg
MAPKAPK2 mediates p38 and ERK signaling in vivo. It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation.
Catalog: PR5320A
Size: 100 µg
Size: 100 µg
RPS6KA3 (RSK2) is a serine⁄threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation.
Catalog: PR5326A
Size: 100 µg
Size: 100 µg
FGFR2 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy.
Catalog: PR5332A
Size: 100 µg
Size: 100 µg
MAPK8 (JNK1) is activated by the presence of malfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity.
Catalog: PR5340A
Size: 100 µg
Size: 100 µg
MAP2K2 (MEK2) is a dual specificity serine⁄threonine kinase that is known to play a critical role in mitogen growth factor signal transduction.
Catalog: PR5399A
Size: 100 µg
Size: 100 µg
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders.
Catalog: PR5442A
Size: 100 µg
Size: 100 µg
CAMK2D (CaMKII delta) is a calmodulin-dependent serine⁄threonine kinase expressed in many cell types. Aberrant expression of CAMK2D has been observed both in tumor cell lines and in the cardiac tissue of patients with dilated cardiomyopathy.
Catalog: PR5448A
Size: 100 µg
Size: 100 µg
Products from Cdk1⁄Cyclin B Recombinant Human Protein to Camk2d (Camkii Delta) Recombinant Human Protein
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