Products from Prkce (Pkc Epsilon) Recombinant Human Protein to Ultrapure™ Bsa (50 Mg/Ml)
The PKC family of serine⁄threonine kinases, including PRKCE (PKC epsilon), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PR1473D
Size: 100 µg
Size: 100 µg
The PKC family of serine⁄threonine kinases, including PRKCE (PKC epsilon), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3609
Size: 1 mg
Size: 1 mg
MINK1 is a serine⁄threonine kinase belonging to the germinal center kinase (GCK) family.
Catalog: PR7198A
Size: 100 µg
Size: 100 µg
MINK1 is a serine⁄threonine kinase belonging to the germinal center kinase (GCK) family.
Catalog: PV4022
Size: 1 mg
Size: 1 mg
The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylation eIF4E on Ser209, and may contribute to tumorigenesis.
Catalog: PR8046A
Size: 100 µg
Size: 100 µg
The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylation eIF4E on Ser209, and may contribute to tumorigenesis.
Catalog: PV5608
Size: 1 mg
Size: 1 mg
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease. Related Links: • LRRK2 tools for advancing Parkinson's disease research • Kinase protein portfolio • LanthaScreen® Eu Kinase Binding Assay • LanthaScreen® Activity Assay
Catalog: PR8604B
Size: 100 µg
Size: 100 µg
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease. Related Links: • LRRK2 tools for advancing Parkinson's disease research • Kinase protein portfolio • LanthaScreen® Eu Kinase Binding Assay • LanthaScreen® Activity Assay
Catalog: PV4874
Size: 1 mg
Size: 1 mg
HIPK2 is a nuclear serine⁄threonine kinase that is linked to transcriptional regulation and apoptosis.
Catalog: PR9004A
Size: 100 µg
Size: 100 µg
HIPK2 is a nuclear serine⁄threonine kinase that is linked to transcriptional regulation and apoptosis.
Catalog: PV5276
Size: 1 mg
Size: 1 mg
NUAK1 (ARK5) is a serine⁄threonine kinase that plays a role in many cellular functions. The overexpression of this kinase has been associated with tumor invasion and metastasis (colorectal neoplasm).
Catalog: PR7569A
Size: 100 µg
Size: 100 µg
NUAK1 (ARK5) is a serine⁄threonine kinase that plays a role in many cellular functions. The overexpression of this kinase has been associated with tumor invasion and metastasis (colorectal neoplasm).
Catalog: PV4283
Size: 1 mg
Size: 1 mg
MAP3K2 (MEKK2) is a serine⁄threonine kinase that activates kinases involved in the MAP kinase signaling pathway.
Catalog: PR7408A
Size: 100 µg
Size: 100 µg
MAP3K2 (MEKK2) is a serine⁄threonine kinase that activates kinases involved in the MAP kinase signaling pathway.
Catalog: PV4010
Size: 1 mg
Size: 1 mg
MST4 is member of the Ste20-like kinase family of serine⁄threonine kinases and is overexpressed during prostate cancer development.
Catalog: PR7067A
Size: 100 µg
Size: 100 µg
MST4 is member of the Ste20-like kinase family of serine⁄threonine kinases and is overexpressed during prostate cancer development.
Catalog: PV4024
Size: 1 mg
Size: 1 mg
BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of cancers.
Catalog: PR7304A
Size: 100 µg
Size: 100 µg
BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of cancers.
Catalog: PV4173
Size: 1 mg
Size: 1 mg
CAMK2B (CaMKII beta) is a serine⁄threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization and regulation of gene expression. As a dominant kinase in the central nervous system it may function in long term potentiation and neurotransmitter release.
Catalog: PR7771A
Size: 100 µg
Size: 100 µg
CAMK2B (CaMKII beta) is a serine⁄threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization and regulation of gene expression. As a dominant kinase in the central nervous system it may function in long term potentiation and neurotransmitter release.
Catalog: PV4278
Size: 1 mg
Size: 1 mg
AMP-activated protein kinase (AMPK) is a heterotrimeric complex that acts as sensor of cellular energy levels. The signaling cascades initiated by activating AMPK are critical to regulating metabolic events in the liver, skeletal muscle, heart, adipose tissue, and pancreas. An impairment in fuel metabolism that occurs in obesity is a factor leading to type 2 diabetes. The insulin resistance associated with type 2 diabetes is most profound at the level of skeletal muscle, the primary site of glucose and fatty acid utilization. Activation of AMPK is of interest for the treatment of type 2 diabet...
Catalog: PV4673
Size: 1 mg
Size: 1 mg
AMP-activated protein kinase (AMPK) is a heterotrimeric complex that acts as a sensor of cellular energy levels. The signaling cascades initiated by activating AMPK are critical to regulating metabolic events in the liver, skeletal muscle, heart, adipose tissue, and pancreas. An impairment in fuel metabolism that occurs in obesity is a factor leading to Type 2 diabetes. The insulin resistance associated with type 2 diabetes is most profound at the level of skeletal muscle, the primary site of glucose and fatty acid utilization. Activation of AMPK is of interest for the treatment of type 2 diab...
Catalog: PV4675
Size: 1 mg
Size: 1 mg
FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.
Catalog: PV4754
Size: 1 mg
Size: 1 mg
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease. This full-length, purified and active LRRK2 G2019S mutant protein may be useful in research to better understand the most common Parkinson's disease-relevant mutant, as well as to explore the mechanisms underlying the disease. • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein • Uncover novel compounds or hits specific to the full-length form • Advan...
Catalog: A15200PT
Size: 10 µg
Size: 10 µg
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease. This full-length, purified and active LRRK2 G2019S mutant protein may be useful in research to better understand the most common Parkinson's disease-relevant mutant, as well as to explore the mechanisms underlying the disease. • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein • Uncover novel compounds or hits specific to the full-length form • Advan...
Catalog: A15201PT
Size: 100 µg
Size: 100 µg
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease. This full-length, purified and active LRRK2 G2019S mutant protein may be useful in research to better understand the most common Parkinson's disease-relevant mutant, as well as to explore the mechanisms underlying the disease. • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein • Uncover novel compounds or hits specific to the full-length form • Advan...
Catalog: A15202PT
Size: 1 mg
Size: 1 mg
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multi-domain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease. This full-length, purified and active wild type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying the disease. • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein • Uncover novel compounds or hits specific to the full-length form • Advance Parkinso...
Catalog: A15197PT
Size: 10 µg
Size: 10 µg
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multi-domain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease. This full-length, purified and active wild type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying the disease. • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein • Uncover novel compounds or hits specific to the full-length form • Advance Parkinso...
Catalog: A15198PT
Size: 100 µg
Size: 100 µg
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multi-domain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease. This full-length, purified and active wild type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying the disease. • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein • Uncover novel compounds or hits specific to the full-length form • Advance Parkinso...
Catalog: A15199PT
Size: 1 mg
Size: 1 mg
Ambion® Ultrapure BSA is a "non-acetylated" BSA pure enough to use when DNA or RNA integrity is critical. One tube containing 50 mg is provided, at a concentration of 50 mg/mL. Bovine Serum Albumin (BSA) has many uses as a carrier protein and as a stabilizing agent in enzymatic reactions. In northern, Southern, and dot blot hybridizations, BSA is also used as a blocking agent. It is recommended in buffers for nick translation, polymerase reactions, and ligations. BSA is also a common additive for PCR amplifications, footprinting, and gel shift assays. In restriction digests, BSA has been shown...
Catalog: AM2616
Size: 1 tube
Size: 1 tube
Products from Prkce (Pkc Epsilon) Recombinant Human Protein to Ultrapure™ Bsa (50 Mg/Ml)
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