Products from Mapk10 (Jnk3) Recombinant Human Protein to Lyn a Recombinant Human Protein
MAPK10 (JNK3) is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). MAPK10 is involved in neuronal apoptosis and phosphorylates MAP2K4.
Catalog: PV4564
Size: 1 mg
Size: 1 mg
MAP3K8 (COT) is a serine⁄threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle.
Catalog: PV4330
Size: 1 mg
Size: 1 mg
The PKC family of serine⁄threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3600
Size: 1 mg
Size: 1 mg
Bone marrow tyrosine kinase (BMX) is a non-receptor tyrosine kinase that belongs to the SRC-related TEC subfamily of tyrosine kinases. It is an important regulator of various cellular processes including apoptosis, cell survival, cellular differentiation, cell migration, and transformation.
Catalog: PV4074
Size: 1 mg
Size: 1 mg
FGFR3 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy.
Catalog: PV4107
Size: 1 mg
Size: 1 mg
TXK, along with the close relatives BMS, ITK, and BTK, signal downstream of antigen receptors and other types of receptors.
Catalog: PV5861
Size: 1 mg
Size: 1 mg
AURKA (Aurora A) is a serine⁄threonine kinase that regulates mitosis by association in vivo with centrosomes. Overexpression of AURKA is observed in many types of cancer.
Catalog: PV4067
Size: 1 mg
Size: 1 mg
EPHA2 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA2 is overexpressed in many types of human cancers.
Catalog: PV4094
Size: 1 mg
Size: 1 mg
EIF2AK2 (PKR) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses. EIF2AK2 plays a key role in antiviral defense mediated through its direct activation by double-stranded RNA produced by viral infection.
Catalog: PV4822
Size: 1 mg
Size: 1 mg
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2.
Catalog: PV4884
Size: 1 mg
Size: 1 mg
This recombinant fusion protein consists of full-length hematopoietic cell kinase (HCK) and a glutathione S-transferase (GST) tag. It is validated in the LanthaScreen® Eu Kinase Binding Assay. No special measures were taken to activate this kinase. • Compatible and validated with the LanthaScreen® Eu Kinase Binding Assay • Expressed in insect cells • GST tagged for use with Eu-labeled GST antibody Easily Screen for Kinase Binding The LanthaScreen® Eu Kinase Binding Assay is a TR-FRET assay that lets you measure inhibitor binding to non-activated kinases, perform simple off-rate measurements, a...
Catalog: PV6129
Size: 1 mg
Size: 1 mg
WEE1, which is classified as a Ser⁄Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation.
Catalog: PV4072
Size: 1 mg
Size: 1 mg
ADRBK1 (GRK2) is a serine⁄threonine kinase. Many of the G protein-coupled receptors are known to be phosphorylated by G protein-dependent receptor kinases (GRKs)
Catalog: PR4694A
Size: 1 mg
Size: 1 mg
RPS6KA6 (RSK4) is a member of the RSK kinases family. RSK family members are activated by ERKs and mitogens and are unusual in that they contain 2 non-identical kinase domains.
Catalog: PV4558
Size: 1 mg
Size: 1 mg
MAPK12 (p38 gamma) is a serine⁄threonine kinase involved in many different cellular processes. It is activated during hypoxia and gamma-irradiation-induced G(2) arrest.
Catalog: PV4016
Size: 1 mg
Size: 1 mg
LIMK1 is a serine⁄threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK1 has also been implicated in brain development.
Catalog: PV4348
Size: 1 mg
Size: 1 mg
Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3. ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.
Catalog: PV4104
Size: 1 mg
Size: 1 mg
PTK2B (FAK2) is a cytoplasmic tyrosine kinase involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway.
Catalog: PV4568
Size: 1 mg
Size: 1 mg
EIF2AK1 (HRI) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK1, signaling is initiated by low levels of heme.
Catalog: PV5857
Size: 1 mg
Size: 1 mg
MLCK (MLCK2), now also known as MYLK3, is of of the myosin regulatory light chain kinases which facilitates muscle contraction.
Catalog: PV4023
Size: 1 mg
Size: 1 mg
KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. The clinically observed V654A mutant has been demonstrated to be resistant to inhibition with imatinib.
Catalog: PV4291
Size: 1 mg
Size: 1 mg
PKN2 (PRK2), a close relative of the PKCs, is a regulator of mitosis and exit from cytokinesis.
Catalog: PV4197
Size: 1 mg
Size: 1 mg
BRSK1 (SAD1) is a serine⁄threonine kinase, and is a UV-induced DNA damage checkpoint kinase
Catalog: PV4344
Size: 1 mg
Size: 1 mg
DMPK is a serine⁄threonine kinase expressed in various muscle and nerve tissues. Mutations in the untranslated region of the DMPK gene are a characteristic of myotonic dystrophy.
Catalog: PV3996
Size: 1 mg
Size: 1 mg
FGFR1 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy.
Catalog: PV4105
Size: 1 mg
Size: 1 mg
PRKG1 is a cGMP-dependent serine⁄threonine kinase which has an important role in the relaxation of vascular smooth muscle and the inhibition of platelet aggregation
Catalog: PV4351
Size: 1 mg
Size: 1 mg
MAPK13 (p38 delta) is a serine⁄threonine kinase that transduces a variety of extracellular signals, including cytokine and environmental stress responses. MAPK13 also regulates the differentiation of keratinocytes.
Catalog: PV4017
Size: 1 mg
Size: 1 mg
GSG2 (haspin) is a conserved kinase required for mitosis. GSG2 phosphorylates histone H3 and is viewed as a potential therapeutic target for oncology.
Catalog: PV5709
Size: 1 mg
Size: 1 mg
The PKC family of serine⁄threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV4044
Size: 1 mg
Size: 1 mg
LYN is a SRC family kinase expressed predominantly in hematopoietic cells. Activation of LYN has been shown to lead to imatinib resistance in CML patients. LYNB and the slightly shorter LYNA are the two isoforms of LYN.
Catalog: PV4082
Size: 1 mg
Size: 1 mg
Products from Mapk10 (Jnk3) Recombinant Human Protein to Lyn a Recombinant Human Protein
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