Products from Nek2 Recombinant Human Protein to Ddr1 Human Protein
NEK2 is involved in cell cycle regulation and is essential for faithful chromosome segregation.
Catalog: PR4616A
Size: 100 µg
Size: 100 µg
MET (cMET) is a receptor-like tyrosine kinase whose disregulation has been linked to many types of human malignancies.
Catalog: PR4563B
Size: 100 µg
Size: 100 µg
DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumour suppressor.
Catalog: PR6332A
Size: 100 µg
Size: 100 µg
The class II PI3 kinases, including PIK3C2B, phosphorylate the 3 position of PI or PI4P. Though not as well studied as the class I PI3 kinases, the class II enyzmes have been linked to diverse, recpetor-mediated cellular processes including insulin signalling, neuronal survival, and growth factor signalling.
Catalog: PR9006A
Size: 100 µg
Size: 100 µg
DAPK2 is a calcium⁄calmodulin-dependent kinase that acts as a positive regulator of apoptosis, and is expressed in many tissue types.
Catalog: PR5688A
Size: 100 µg
Size: 100 µg
PRKG2 (PKG2) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity.
Catalog: PR7572A
Size: 100 µg
Size: 100 µg
CSNK2A1 is a serine⁄threonine protein kinase that phosphorylates acidic proteins.
Catalog: PR4554A
Size: 100 µg
Size: 100 µg
PRKC1 (PKC mu) is a serine⁄threonine protein kinase that is phospholipid-dependant and activated by diacylglycerol and phorbol ester TPA. PRKC1 behaves similarly to most PKC isoenzymes of the PKC family, however, PRKC1 differs in some structural and enzymatic features from the other PKC isotypes, and has been shown to be involved in the signal transduction of a wide range of biological responses.
Catalog: PR7258C
Size: 100 µg
Size: 100 µg
CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, and is essential for cell cycle G1⁄S phase transition. This protein is coexpressed and copurified with CyclinA.
Catalog: PR4448B
Size: 100 µg
Size: 100 µg
SGK2 is a serine⁄threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGK2 is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK.
Catalog: PR7313A
Size: 100 µg
Size: 100 µg
SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine producing the signalling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapuetics for the treatment of cancer.
Catalog: PR8935A
Size: 100 µg
Size: 100 µg
ITK is a tyrosine kinase expressed in T-cells which contains both SH2 and SH3 domains. ITK is thought to play a role in T-cell proliferation and differentiation.
Catalog: PR6992A
Size: 100 µg
Size: 100 µg
ADRBK2, or adrenergic beta receptor kinase 2 is a serine⁄threonine kinase that is thought to act as a regulator of receptor function.
Catalog: PR7122A
Size: 100 µg
Size: 100 µg
STK22B (TSSK2) is a serine⁄threonine kinase essential for the function and production of sperm (spermiogenesis). Deletions in the STK22B coding region correlate with numerous cardiovascular and glandular malformations.
Catalog: PR5947A
Size: 100 µg
Size: 100 µg
PKN1 (PRK1) belongs to the protein kinase C superfamily. This kinase is activated by the Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can also be activated by phospholipids.
Catalog: PR7255B
Size: 100 µg
Size: 100 µg
EPHA8 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA8 plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
Catalog: PR7298B
Size: 100 µg
Size: 100 µg
EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system.
Catalog: PR6419A
Size: 100 µg
Size: 100 µg
RPS6KA2 (RSK3) is a serine-threonine kinase that is part of the ribosomal S6 kinase family and the subfamily of insulin⁄mitogen-stimulated kinases. It is thought that RPS6KA2 is a signal-transducing intermediate in the cellular response to several growth factors. It is found in many tissues, but in higher levels in lung and skeletal muscle.
Catalog: PR5813A
Size: 100 µg
Size: 100 µg
CSK is a tyrosine kinase that has been shown to downregulate the activity of SRC oncoprotein through phosphorylation of its carboxy terminus. Since cell transformation by SRC is caused by various mechanisms that interfere with this phosphorylation, the CSK gene might function as an antioncogene.
Catalog: PR3080B
Size: 100 µg
Size: 100 µg
PTK2 (FAK) is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents.
Catalog: PR7495A
Size: 100 µg
Size: 100 µg
MAP3K9 (MLK1) is a serine⁄threonine protein kinase that functions in the MAP kinase pathway.
Catalog: PR7007A
Size: 100 µg
Size: 100 µg
EPHB4 is a receptor tyrosine kinase that belongs to the ephrin receptor family. Members of the Eph family of kinases play important roles in diverse biological processes including nervous system development, angiogenesis and neural synapsis formation and maturation.
Catalog: PR4688B
Size: 100 µg
Size: 100 µg
PRKX is a serine⁄threonine kinase related to the catalytic subunit of the cAMP-dependent protein kinases.
Catalog: PR7204A
Size: 100 µg
Size: 100 µg
RPS6KB2 (p70S6K beta) is a serine⁄threonine kinase with 2 non-identical kinase catalytic domains which phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Catalog: PR7468B
Size: 100 µg
Size: 100 µg
STK24 (MST3) is a serine⁄threonine kinase that is a member of the GCK subfamily of STE20-like proteins.
Catalog: PR6359A
Size: 100 µg
Size: 100 µg
The PKC family of serine⁄threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PR1476D
Size: 100 µg
Size: 100 µg
AKT3 (PKB gamma) has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). It is involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, glycogen synthesis and glucose uptake.
Catalog: PR4643B
Size: 100 µg
Size: 100 µg
RIPK2 is a serine⁄threonine kinase that is involved in cell activation, proliferation, differentiation, and apoptosis.
Catalog: PR7829A
Size: 100 µg
Size: 100 µg
PI4KB and PI4KA are the two human type III PI4 kinases, which share sequence similarly with PI3 kinases and phosphorylate the 4 position of phosphotidyl inositol.
Catalog: PR9056A
Size: 100 µg
Size: 100 µg
DDR1 is a receptor tyrosine kinase activated by collagen and is reported to regulate adhesion, cell migration and other cellular processes.
Catalog: PR6913A
Size: 100 µg
Size: 100 µg
Products from Nek2 Recombinant Human Protein to Ddr1 Human Protein
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