Products from Grk4 Recombinant Human Protein to Mark3 Recombinant Human Protein

GRK4 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

GRK4 is a member of the G protein-coupled receptor kinase subfamily of the serine⁄threonine protein kinase family. GRK4 phosphorylates the activated forms of G protein-coupled receptors.
Catalog: PV3999
Size: 1 mg

PI4KB (PI4K beta) Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Lipid Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Lipid Kinases

PI4KB and PI4KA are the two human type III PI4 kinases, which share sequence similarly with PI3 kinases and phosphorylate the 4 position of phosphotidyl inositol.
Catalog: PV5278
Size: 1 mg

CAMKK2 (CaMKK Beta) Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CAMKK2 (CaMKK beta) is a serine⁄threonine kinase involved in neurogenesis, cell differentiation, and signal transduction. It also activates CAMKI and CAMKIV, and plays a role in the development of long term memory.
Catalog: PV4322
Size: 1 mg

KIT [T670I] Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. KIT T670I is a Gleevec resistant form of KIT.
Catalog: PV4187
Size: 1 mg

DYRK1B Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

DYRK1B is a member of the DYRK family of protein kinases and is proposed to be involved in nuclear functions.
Catalog: PV4650
Size: 1 mg

SLK Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

SLK acts as a novel effector of cytoskeletal remodeling and apoptosis, and seems to be ubiquitously expressed.
Catalog: PV4059
Size: 1 mg

MAP4K5 (KHS1) Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MAP4K5 (KHS1) is a serine⁄threonine kinase that belongs to the GCK family of kinases and has been implicated as an upstream regulator of MAP kinase signaling pathways.
Catalog: PV4014
Size: 1 mg

LRRK2 [D1994A] Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Certain mutations (e.g. I2020T, G2019S, and R1441C) in this gene have been associated with Parkinson's disease. D1994A is an artificial mutation that renders the kinase catalytically inactive and thus serves as a useful control for activity assays, especially when testing novel substrates. Related Links: • LRRK2 tools for advancing Parkinson's disease research • Kinase protein portfolio • LanthaScreen® Eu Kinase Binding Assay • LanthaScreen® Activity Assay
Catalog: PV6052
Size: 1 mg

CLK1 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CLK1 is a dual specificity kinase that phosphorylates PTP-1B and members of the SR family of splicing factors. It is thought to be involved in neuronal differentiation and mRNA splicing.
Catalog: PV3984
Size: 1 mg

LIMK2 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

LIMK2 is a serine⁄threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK2 has also been implicated in brain development.
Catalog: PV4349
Size: 1 mg

CDK9⁄Cyclin K Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CDK9 is a serine⁄threonine kinase that phosphorylates the c-terminal domain of the largest subunit of RNA polymerase II and is involved in cell cycle regulation, This protein is coexpressed and copurified with CyclinK.
Catalog: PV4346
Size: 1 mg

ROCK1 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

ROCK1 is a serine⁄threonine kinase that regulates cell differentiation and migration. The Rho⁄ROCK pathway is involved in the progression of various human cancers.
Catalog: PR7028A
Size: 1 mg

GRK7 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

GRK7 is a serine⁄threonine kinase that is specifically expressed in the retina and phosphorylates cone opsins and initiates their deactivation.
Catalog: PV4125
Size: 1 mg

LRRK2 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease. Related Links: • LRRK2 tools for advancing Parkinson's disease research • Kinase protein portfolio • LanthaScreen® Eu Kinase Binding Assay • LanthaScreen® Activity Assay
Catalog: PV4874
Size: 1 mg

SeqSphere+ Software from Ridom allows for automatic processing and analyzing of microbial sequence data obtained from Ion Torrent™ systems. SeqSphere+ Software enables whole genome microbial typing (MLST+), traditional MLST, or 16S rDNA sequencing projects. This software is designed both for individual labs and for distributed work-groups (client/server model) to enable easy data sharing. License options are available for 1, 3, or 5 years; 2 or 5 seats; and commercial or academic/government labs. Ridom SeqSphere+ Software Features: • User-friendly: no scripting skills or bioinformatician neede...
Catalog: 4483696
Size: 1 each

BigDye® Terminator v3.1 Cycle Sequencing Kit, Products & Services > Kits & Assays > Sequencing Kits & Reagents > Sequencing Kits

Category: Products & Services > Kits & Assays > Sequencing Kits & Reagents > Sequencing Kits

The BigDye® Terminator v3.1 Cycle Sequencing Kit's robust, highly flexible chemistry is ideal for de novo sequencing, resequencing, and finishing with PCR product, Plasmid, Fosmid, and BAC templates. • Improve the quality of your results for a wide range of sequencing applications. • Optimized for long read lengths. • Better dye mobility characteristics • Improved performance reading through GT rich regions. • Get longer, higher-quality reads with more uniform peak heights and optimal signal balance. • Enhance your productivity and reduce costs. Get More Uniform Peak Heights, Improved Accuracy...
Catalog: 4337456
Size: 1000 reactions

GripTite™ 293 MSR Cell Line, Products & Services > Eukaryotic Cells > Cell Lines > Mammalian Cell Lines

Category: Products & Services > Eukaryotic Cells > Cell Lines > Mammalian Cell Lines

The GripTite™ 293 MSR Cell Line is a genetically engineered Human Embryonic Kidney (HEK 293) cell line that expresses the human macrophage scavenger receptor and strongly adheres to standard tissue culture plates for dependable results. Developed from a 293-H subclone, GripTite™ 293 MSR cells show the same fast cell growth, high transfection efficiency, and high-level expression characteristics of the parental 293-H cells. Unlike most 293 cells, GripTite® 293 MSR cells dont wash away during the repeated manipulations of routine tissue culture or plate washing protocols (Figure 1). Their superi...
Catalog: R795-07
Size: 1 kit

LanthaScreen® Eu-anti-GST (Rabbit) Antibody, Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > Tr-Fret Primary Antibodies

Category: Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > TR-FRET Primary Antibodies

LanthaScreen® europium-labeled anti-GST rabbit antibodies are used to indirectly label proteins tagged with GST. This can be advantageous when working with partially purified protein, or in cases in which direct labeling of the protein using amine-reactive Eu chelates negatively impacts protein activity. These antibodies can be used with our Kinase Tracers to conduct LanthaScreen® Eu Kinase Binding Assays.
Catalog: A15117
Size: 1 mg

LanthaScreen® Tb-anti-GST (Rabbit) Antibody, Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > Tr-Fret Primary Antibodies

Category: Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > TR-FRET Primary Antibodies

LanthaScreen® terbium-labeled anti-GST Rabbit antibodies are used to indirectly label proteins tagged with GST. This can be advantageous when working with partially purified protein, or in cases in which direct labeling of the protein using amine-reactive Tb chelates negatively impacts protein activity.
Catalog: A15114
Size: 1 mg

SRMS (SRM) Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

SRMS (Srm) is a tyrosine protein kinase (SRC sub-family) that may be involved in the proliferation and differentiation of keratinocytes.
Catalog: PV4287
Size: 1 mg

JAK1 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

Janus kinase 1 (JAK1), is a protein tyrosine kinase that is involved in the interferon-alpha⁄beta and -gamma signal transduction pathways.
Catalog: PV4775
Size: 1 mg

DYRK1A Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21, and has been implicated in the pathogenesis of this disease.
Catalog: PV3997
Size: 1 mg

AKT1 (PKB alpha) Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

AKT1 (PKB alpha) is a serine⁄threonine kinase that regulates cell survival. The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells.
Catalog: PV3599
Size: 1 mg

CDK9⁄Cyclin T1 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CDK9 is a serine⁄threonine kinase which when complexed with CyclinT1 forms an active holoenzyme complex. This complex plays a key role in regulating the eukaryotic cell cycle. CDK9 is coexpressed and copurified with CyclinT1.
Catalog: PV4280
Size: 1 mg

ABL1 [Y253F] Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The Y253F mutant is a Gleevec resistant form of ABL1.
Catalog: PV4181
Size: 1 mg

HIPK3 (YAK1) Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

HIPK3 is a serine⁄threonine kinase involved in signal transduction, cellular communication, and multidrug resistance of tumors and plays a role in the phosphorylation of FADD.
Catalog: PV4324
Size: 1 mg

CLK4 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

CLK4 belongs to the CDC2-like protein kinase (CLK) family. It can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus is thought to be involved in the regulation of alternative splicing.
Catalog: PV3986
Size: 1 mg

TYK2 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Cytoplasmic Tyrosine Kinases

Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling.
Catalog: PV4791
Size: 1 mg

IKBKE (IKK Epsilon) Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

IKBKE is an activator of nuclear factor-kappa-B. Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death.
Catalog: PV4876
Size: 1 mg

MARK3 Recombinant Human Protein, Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases

MARK3 is a member of a group of kinases known to regulate cell polarity via phosphorylation of microtubule-associated proteins (MAPs).
Catalog: PV4820
Size: 1 mg