Products from Tek (Tie2) Recombinant Human Protein to Cdk2⁄Cyclin a Recombinant Human Protein
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells. TEK signaling appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, and defects in TEK are associated with inherited venous malformations.
Catalog: PR6314A
Size: 100 µg
Size: 100 µg
PRKACA (PKA) is a serine⁄threonine protein kinase that phosphorylates a broad spectrum of substrates. PRKACA regulates many cellular processes including cell growth, cell differentiation, ion-channel conductivity, gene transcription, and synaptic release of neurotransmitters.
Catalog: PR3791B
Size: 100 µg
Size: 100 µg
SGKL (SGK3) is a serine⁄threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGKL is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK.
Catalog: PR7301A
Size: 100 µg
Size: 100 µg
MARK2 is a serine⁄threonine protein kinase involved in the control of cell polarity and microtubule stability.
Catalog: PR7405A
Size: 100 µg
Size: 100 µg
MERTK (cMER) is a tyrosine kinase proto-oncogene and is involved in the retinal pigment epithelium (RPE) phagocytosis pathway, which is implicated in human retinal disease.
Catalog: PR6317A
Size: 100 µg
Size: 100 µg
RPS6KA5 (MSK1) is a serine⁄threonine protein kinase that is essential for the regulation of various cellular processes.
Catalog: PR6891A
Size: 100 µg
Size: 100 µg
TYRO3 is a receptor tyrosine kinase that has been shown to be involved in signal transduction and cell adhesion.
Catalog: PR7480A
Size: 100 µg
Size: 100 µg
FES (FPS) is a tyrosine protein kinase that is required for maintenance of cellular transformation. Its chromosomal location is linked to a specific translocation event identified in patients with acute promyelocytic leukemia, and it is also involved in normal hematopoiesis.
Catalog: PR5068B
Size: 100 µg
Size: 100 µg
ROS1 is a tyrosine kinase that functions as a growth or differentiation factor receptor.
Catalog: PR7292A
Size: 100 µg
Size: 100 µg
MAPK8 (JNK1) is activated by the presence of malfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity.
Catalog: PR5340A
Size: 100 µg
Size: 100 µg
EPHA7 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA7 is involved in embryonic development.
Catalog: PR7046A
Size: 100 µg
Size: 100 µg
This recombinant fusion protein consists of full-length glycogen synthase kinase 3 alpha (GSK3A) and a glutathione S-transferase (GST) tag. It is validated in the LanthaScreen® Eu Kinase Binding Assay. No special measures were taken to activate this kinase. • Compatible and validated with the LanthaScreen® Eu Kinase Binding Assay • Expressed in insect cells • GST tagged for use with Eu-labeled GST antibody Easily Screen for Kinase Binding The LanthaScreen® Eu Kinase Binding Assay is a TR-FRET assay that lets you measure inhibitor binding to non-activated kinases, perform simple off-rate measur...
Catalog: PR9188A
Size: 100 µg
Size: 100 µg
PDGFRB is a receptor tyrosine kinase and has been implicated in atherogenesis and in cell transformation by the SIS oncogene.
Catalog: PR4465B
Size: 100 µg
Size: 100 µg
MAP3K3 (MEKK3) directly regulates MAPK8 and extracellular signal-regulated protein kinase (ERK) pathways by phosphorylating multiple MAP2Ks.
Catalog: PR7352A
Size: 100 µg
Size: 100 µg
PAK4 is a serine⁄ threonine p21 activating kinase implicated in the reorganization of actin cytoskeleton and in the formation of filopodia.
Catalog: PR7856A
Size: 100 µg
Size: 100 µg
CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, which encodes serine⁄threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric, ranging from 25 to 55 kD, and are found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells.
Catalog: PR7361B
Size: 100 µg
Size: 100 µg
STK23 (MSSK1), also known as SRPK3, is a muscle-specific member of the SRPKs.
Catalog: PR7207A
Size: 100 µg
Size: 100 µg
CAMK2D (CaMKII delta) is a calmodulin-dependent serine⁄threonine kinase expressed in many cell types. Aberrant expression of CAMK2D has been observed both in tumor cell lines and in the cardiac tissue of patients with dilated cardiomyopathy.
Catalog: PR5448A
Size: 100 µg
Size: 100 µg
PASK is an evolutionarily conserved protein present in yeast, flies, and mammals. PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli.
Catalog: PR7013A
Size: 100 µg
Size: 100 µg
DDR2 is a member of a subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. DDR1 and DDR2 have been shown to be potently inhibited by Gleevec.
Catalog: PR7167A
Size: 100 µg
Size: 100 µg
The PKC family of serine⁄threonine kinases, including PRKCB2 (PKC beta II), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PR1461C
Size: 100 µg
Size: 100 µg
NEK2 is involved in cell cycle regulation and is essential for faithful chromosome segregation.
Catalog: PR4616A
Size: 100 µg
Size: 100 µg
MET (cMET) is a receptor-like tyrosine kinase whose disregulation has been linked to many types of human malignancies.
Catalog: PR4563B
Size: 100 µg
Size: 100 µg
DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumour suppressor.
Catalog: PR6332A
Size: 100 µg
Size: 100 µg
The class II PI3 kinases, including PIK3C2B, phosphorylate the 3 position of PI or PI4P. Though not as well studied as the class I PI3 kinases, the class II enyzmes have been linked to diverse, recpetor-mediated cellular processes including insulin signalling, neuronal survival, and growth factor signalling.
Catalog: PR9006A
Size: 100 µg
Size: 100 µg
DAPK2 is a calcium⁄calmodulin-dependent kinase that acts as a positive regulator of apoptosis, and is expressed in many tissue types.
Catalog: PR5688A
Size: 100 µg
Size: 100 µg
PRKG2 (PKG2) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity.
Catalog: PR7572A
Size: 100 µg
Size: 100 µg
CSNK2A1 is a serine⁄threonine protein kinase that phosphorylates acidic proteins.
Catalog: PR4554A
Size: 100 µg
Size: 100 µg
PRKC1 (PKC mu) is a serine⁄threonine protein kinase that is phospholipid-dependant and activated by diacylglycerol and phorbol ester TPA. PRKC1 behaves similarly to most PKC isoenzymes of the PKC family, however, PRKC1 differs in some structural and enzymatic features from the other PKC isotypes, and has been shown to be involved in the signal transduction of a wide range of biological responses.
Catalog: PR7258C
Size: 100 µg
Size: 100 µg
CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, and is essential for cell cycle G1⁄S phase transition. This protein is coexpressed and copurified with CyclinA.
Catalog: PR4448B
Size: 100 µg
Size: 100 µg
Products from Tek (Tie2) Recombinant Human Protein to Cdk2⁄Cyclin a Recombinant Human Protein
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