Products from Parp1 Recombinant Human Protein, his Tag to Lrrk2 [I2020t] Human Protein
Poly (Adp-Ribose) Polymerase 1 (PARP1), recombinant human protein is supplied in frozen format. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from The amino acids corresponding to the full length of human PARP1 (NP_001609.2) (Met 1-Trp 1014) fused to a polyhistidine tag at the C-terminus. Activity: Measured by its binding ability in a functional ELISA. Immobiliz...
Catalog: 11040-H08B-250
Size: 5 × 50 µg
Size: 5 × 50 µg
Lectin, galactoside-binding, soluble, 3 (LGALS3), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications. This recombinant protein was expressed from a DNA sequence encoding the human LGALS3 (P17931) (Met 1-Ile 250). Activity: Measured by its ability to agglutinate human red blood cells. The ED 50 for this effect is typically 3-15 µg/ml. Formulation: Lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na 2 HPO...
Catalog: 10289-HNAE-E-250
Size: 5 × 50 µg
Size: 5 × 50 µg
IL12A & IL12B Heterodimer (IL12A & IL12B), recombinant mouse protein is supplied as a lyophilized powder. This recombinant protein was expressed from a DNA sequence encoding the p35 subunit of mouse IL12, termed as IL12A (P43431) (Met 1-Ala 215) fused to the Fc region of human IgG1 at the C-terminus, constructed the plasmid 1; a DNA sequence encoding the p40 subunit of mouse IL12, termed as IL12B (P43432) (Met 1-Ser 335) fused to the Fc region of human IgG1 at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the heterodimer was purified. Activity: This recombin...
Catalog: CT021-M02H-250
Size: 5 × 50 µg
Size: 5 × 50 µg
Analytical teams that support biologic drug development require rapid, sensitive, and precise methods for protein quantitation from cell culture, fermentations broths, or purification intermediates. It is critical for biopharmaceutical manufacturers to be able to monitor bioreactor product titers to determine when to harvest or abort a reactor cycle. POROS® CaptureSelect® FSH HPLC columns incorporate the advantages of high-speed POROS® chromatography resins with the unique selectivity of CaptureSelect® ligands, enabling 3-minute quantitation of human follicle stimulating hormone (FSH). Feature...
Catalog: 4481826
Size: 1 each
Size: 1 each
AMP-activated protein kinase (AMPK) is a heterotrimeric complex that acts as sensor of cellular energy levels. The signaling cascades initiated by activating AMPK are critical to regulating metabolic events in the liver, skeletal muscle, heart, adipose tissue, and pancreas. An impairment in fuel metabolism that occurs in obesity is a factor leading to type 2 diabetes. The insulin resistance associated with type 2 diabetes is most profound at the level of skeletal muscle, the primary site of glucose and fatty acid utilization. Activation of AMPK is of interest for the treatment of type 2 diabet...
Catalog: PR8376C
Size: 100 µg
Size: 100 µg
JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2.
Catalog: PR8078A
Size: 100 µg
Size: 100 µg
AMP-activated protein kinase (AMPK) is a heterotrimeric complex that acts as a sensor of cellular energy levels. The signaling cascades initiated by activating AMPK are critical to regulating metabolic events in the liver, skeletal muscle, heart, adipose tissue, and pancreas. An impairment in fuel metabolism that occurs in obesity is a factor leading to Type 2 diabetes. The insulin resistance associated with type 2 diabetes is most profound at the level of skeletal muscle, the primary site of glucose and fatty acid utilization. Activation of AMPK is of interest for the treatment of type 2 diab...
Catalog: PR8694C
Size: 100 µg
Size: 100 µg
JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. This kinase contains both the JH1 (catalytic) and JH2 (pseudokinase) domains of JAK2. The V617F mutation has been shown to be a cause of polycythemia vera.
Catalog: PR8134A
Size: 100 µg
Size: 100 µg
The Applied Biosystems® MicroAmp® Optical 384-Well Reaction Plate with barcode is designed to provide unmatched temperature accuracy and uniformity for fast, efficient PCR amplification. This plate, constructed from a single rigid piece of polypropylene in a 384-well format, is designed to work with Applied Biosystems® 384-well Real-Time PCR Systems and Thermal Cyclers. • Frosted to minimize interfering fluorescence from wells of cycling block • Screened to eliminate auto-fluorescent plates • Unique design provides a barrier to ambient air to help insure well-to-well temperature uniformity • E...
Catalog: 4326270
Size: 500 plates
Size: 500 plates
Ambion® Silencer ® SelectGAPDH Positive Control siRNA, In Vivo Ready is extensively validated and an ideal control for many aspects of an siRNA experiment. The control is highly purified as required for animal use. 250 nmol is provided. • Premium-quality siRNA, highly purified and ready to use • Functionally tested in several common cell lines • Include Silencer ® Select modifications for enhanced specificity • For use in human, mouse, and rat cells What are Silencer ® Select siRNAs? Silencer ® Select siRNAs incorporate the latest improvements in siRNA design, off-target effect prediction algo...
Catalog: 4404024
Size: 250 nmol
Size: 250 nmol
This fluorite objective is ideal for fluorescence and demanding transmitted-light applications. This is a coverslip-corrected objective that is optimized for imaging through #1.5 coverslips. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications. Additional characteristics of this EVOS® objective: • Magnification: 100X • Numerical Aperature: 1.28 • Working Distance: 0.21 mm • Immersion: Oil Image Quality Microscope objectives may be ...
Catalog: AMEP4700
Size: 1 each
Size: 1 each
ADAM metallopeptidase domain 12 (ADAM12), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein stucture analysis and in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the human ADAM12 isoform 1 (NP_003465.3) extracellular domain (Met 1-Ser 513) fused to a polyhistidine tag at the C-terminus. Activity: This recombinant protein has not been tested. Formulation: 140 mM NaCl, 2.7 mM KCl, 10 mM Na 2 HPO 4 , 1.8 mM KH 2 PO 4 , pH7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween80. Rec...
Catalog: 10896-H08H-250
Size: 5 × 50 µg
Size: 5 × 50 µg
ADAM metallopeptidase domain 9 (ADAM9), recombinant mouse protein is supplied as a lyophilized powder. In general, recombinant proteins can be used as protein stucture analysis and in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the mouse ADAM9 (Q61072) extracellular domain (Met 1-Asp 697) fused to a C-terminal polyhistidine tag. Activity: This recombinant protein has not been tested. Formulation: 140 mM NaCl, 2.7 mM KCl, 10 mM Na 2 HPO 4 , 1.8 mM KH 2 PO 4 , pH7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween80. Reconstitution: Dissolve the...
Catalog: 50044-M08H-250
Size: 5 × 50 µg
Size: 5 × 50 µg
The PichiaPink™ Secreted Protein Expression Kit is a new recombinant protein expression system based on the yeast Pichia pastoris . The PichiaPink™ Secreted Protein Expression Kit gives you convenient and cost-efficient bioproduction from shake flask to 1000-liter production of your recombinant protein. The PichiaPink™ Secreted Protein Expression Kit comes with our new Pichia strains, the pPINK-HC and pPINK-LC vectors, and secretion signal sequences for production of your protein. • Get started with secreted protein production in Pichia pastoris . • Screen your Pichia transformants rapidly by ...
Catalog: A11151
Size: 1 kit
Size: 1 kit
Plasminogen activator, urokinase (PLAU) activated by trypsin, recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the human PLAU (NP_002649.1) (Met 1-Leu 431) fused to the polyhistidine tag at the C-terminus. The purified protein was activated by trypsin in vitro. Activity: Mea...
Catalog: 10815-H08H-A-250
Size: 5 × 50 µg
Size: 5 × 50 µg
This is a 1-year Advanced Support Agreement for a workgroup license serving up to 10 users of Vector NTI® Express Designer. Our Advanced Support Agreement includes unlimited license support (e.g., re-registration or transfer of a license), telephone and e-mail technical support, and access to all updates and upgrades during the period of the agreement. Without an Advanced Support Agreement you will receive one courtesy license support engagement, e-mail-only technical support, and no updates or upgrades (upgrade licenses can be purchased separately as needed). Vector NTI® Express Designer take...
Catalog: A15333
Size: 1 each
Size: 1 each
Plasminogen activator, urokinase (PLAU), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the human PLAU (NP_002649.1) (Met 1-Leu 431) fused to the polyhistidine tag at the C-terminus. Activity: Measured by its binding ability in a functional ELISA . Immobilized human PLAU a...
Catalog: 10815-H08H-250
Size: 5 × 50 µg
Size: 5 × 50 µg
A 1-year Extended Warranty for your StepOne™ Real-Time PCR System will add 1 year of coverage to the existing warranty. With this extended warranty, your StepOne™ Real-Time PCR System is covered by our Rapid Exchange Service* protection plan. Should you encounter an issue with your instrument, call technical support and talk to one of our Certified Senior Technical Specialists to get assistance in resolving most technical problems. In the event that your instrument needs service, simply repackage the defective instrument and return it to us – we will pay the shipping costs. We will then send a...
Catalog: ZGEXSCSTEPONE
Size: 1 each
Size: 1 each
This fluorite objective is ideal for fluorescence and demanding transmitted-light applications. This is a long working distance (LWD) objective that is optimized for the imaging of slides, cell culture dishes and flasks, and microtiter plates. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications. Additional characteristics of this EVOS® objective: • Magnification: 60X • Numerical Aperature: 0.75 • Working Distance: 2.2 mm Image Qua...
Catalog: AMEP4626
Size: 1 each
Size: 1 each
Interleukin 3 receptor, alpha (low affinity) (IL3RA), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the human IL3RA (NP_002174.1) extracellular domain (Met 1-Arg 305) fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. Activity: Measure...
Catalog: 10518-H03H-250
Size: 5 × 50 µg
Size: 5 × 50 µg
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease. This full-length, purified and active LRRK2 G2019S mutant protein may be useful in research to better understand the most common Parkinson's disease-relevant mutant, as well as to explore the mechanisms underlying the disease. • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein • Uncover novel compounds or hits specific to the full-length form • Advan...
Catalog: A15201PT
Size: 100 µg
Size: 100 µg
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multi-domain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease. This full-length, purified and active wild type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying the disease. • Increase disease relevance by interrogating a purified and active full-length LRRK2 protein • Uncover novel compounds or hits specific to the full-length form • Advance Parkinso...
Catalog: A15198PT
Size: 100 µg
Size: 100 µg
This is a conversion from a dynamic and seat license to a static, non-expiring license for Vector NTI® Express Designer. Vector NTI® Express Designer takes you beyond traditional sequence analysis and design and into the new frontier of rational bio-design. Vector NTI® Express Designer was designed for synthetic biology, metabolic engineering, genetic engineering, and molecular biology professionals who want to rationally design, characterize, assemble, re-factor, and reuse genetic "parts," "devices," and "circuits"—ultimately to standardize, automate, and optimize genetic components for use w...
Catalog: A15325
Size: 1 each
Size: 1 each
The resDNASEQ® MDCK Residual DNA Quantitation Kit is a quantitative PCR (qPCR)-based system for the detection of host cell DNA from MDCK (canine kidney) cells, an expression system commonly used for the production of vaccines. Reliable and rapid, the resDNASEQ® system enables sensitive (as low as 1.5 pg DNA/mL test sample) and specific quantitation of MDCK cell DNA. This performance helps ensure a high degree of confidence in quantitation data obtained from a broad range of sample types—from in-process samples to final product—whether the sample contains high molecular weight or sheared DNA. T...
Catalog: 4464335
Size: 100 reactions
Size: 100 reactions
The resDNASEQ® NS0 Residual DNA Quantitation Kit is a quantitative PCR (qPCR)-based system for the detection of host cell DNA from NS0 (murine myeloma) cells, an expression system commonly used for the production of vaccines. Reliable and rapid, the resDNASEQ® system enables sensitive (as low as 1.5 pg DNA/mL test sample) and specific quantitation of NS0 cell DNA. This performance helps ensure a high degree of confidence in quantitation data obtained from a broad range of sample types—from in-process samples to final product—whether the sample contains high molecular weight or sheared DNA. Thi...
Catalog: 4458441
Size: 100 reactions
Size: 100 reactions
The resDNASEQ® Pichia pastoris Residual DNA Quantitation Kit is a quantitative PCR (qPCR)-based system for the detection of host cell DNA from Pichia pastoris cells, an expression system commonly used for the production of recombinant proteins. Reliable and rapid, the resDNASEQ® system enables sensitive (as low as 15 pg DNA/mL test sample) and specific quantitation of Pichia pastoris cell DNA. This performance helps ensure a high degree of confidence in quantitation data obtained from a broad range of sample types—from in-process samples to final product—whether the sample contains high molecu...
Catalog: 4464336
Size: 100 reactions
Size: 100 reactions
The ViraPower™ HiPerform™ Lentiviral FastTiter™ TOPO® Expression Kit includes all the components needed to generate lentivirus, including vector kit, 293FT cell line, and the support kit. This kit combines Invitrogen’s ViraPower™ HiPerform™ Lentiviral and TOPO® technologies to facilitate quick PCR-based cloning and lentiviral-based, high-level expression of a target gene in dividing and non-dividing mammalian cells. The pLenti7.3/V5-TOPO® vector is equipped with two key genetic elements, making it a HiPerform™ vector: the Woodchuck Posttranscriptional Regulatory Element (WPRE) and the central ...
Catalog: K5320-00
Size: 1 kit
Size: 1 kit
DYRK3 belongs to the DYRK family of dual-specificity protein kinases that catalyze phosphorylation of serine⁄threonine and tyrosine residues. The members of this family share structural similarity, but differ in their substrate specificity, suggesting their involvement in different cellular functions.
Catalog: PR7492A
Size: 100 µg
Size: 100 µg
CAMKK1 (CAMKKA) is a serine⁄threonine protein kinase family member, and belongs to the Ca2+⁄calmodulin-dependent protein kinase subfamily.
Catalog: PR8308A
Size: 100 µg
Size: 100 µg
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease, including the I2020T mutation in the kinase catalytic domain. Related Links: • LRRK2 tools for advancing Parkinson's disease research • Kinase protein portfolio • LanthaScreen® Eu Kinase Binding Assay • LanthaScreen® Activity Assay
Catalog: PR8755A
Size: 100 µg
Size: 100 µg
Products from Parp1 Recombinant Human Protein, his Tag to Lrrk2 [I2020t] Human Protein
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