Products from Ret Recombinant Human Protein to Taqman® Pcr Core Reagent Kit (10-Pack)
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement.
Catalog: PV4119
Size: 1 mg
Size: 1 mg
AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome⁄spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction.
Catalog: PV4178
Size: 1 mg
Size: 1 mg
STK4 (MST1) is a serine⁄threonine kinase which may be involved in apoptosis. It is possible that this protein induces the chromatin condensation observed in this process.
Catalog: PV4177
Size: 1 mg
Size: 1 mg
DAPK3 is a serine⁄threonine kinase which is functionally linked to cell motility, smooth muscle contractility and cell death processes.
Catalog: PV3995
Size: 1 mg
Size: 1 mg
CSNK1G2 (CK1 gamma 2) is a serine⁄threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis.
Catalog: PV3990
Size: 1 mg
Size: 1 mg
The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylating eIF4E on Ser209, and may contribute to tumorigenesis.
Catalog: PV6024
Size: 1 mg
Size: 1 mg
EPHA3 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA3 encodes a protein that binds ephrin-A ligands.
Catalog: PV4095
Size: 1 mg
Size: 1 mg
PBK (TOPK) is a serine⁄threonine kinase that is related to the dual specific mitogen-activated protein kinase kinase (MAPKK). The kinase is up-regulated in a variety of hematological malignancies, participates in activating lymphoid cells, and supports testicular function (spermatogenesis).
Catalog: PV4285
Size: 1 mg
Size: 1 mg
ACVR1B is a serine⁄threonine kinase involved in signal transduction and cellular communication. Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors. Mutations of ACVR1B have been observed in pancreatic adenocarcinomas.
Catalog: PV4329
Size: 1 mg
Size: 1 mg
The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Catalog: PV4186
Size: 1 mg
Size: 1 mg
IL-1 receptor associated kinases (IRAKs) are serine⁄threonine kinases involved in signaling via Toll⁄IL-1 pathways.
Catalog: PV4439
Size: 1 mg
Size: 1 mg
The PKC family of serine⁄threonine kinases, including PRKCE (PKC epsilon), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3609
Size: 1 mg
Size: 1 mg
LYN is a SRC family kinase expressed predominantly in hematopoietic cells. Activation of LYN has been shown to lead to imatinib resistance in CML patients. LYNB and the slightly shorter LYNA are the two isoforms of LYN.
Catalog: PV4083
Size: 1 mg
Size: 1 mg
MINK1 is a serine⁄threonine kinase belonging to the germinal center kinase (GCK) family.
Catalog: PV4022
Size: 1 mg
Size: 1 mg
The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylation eIF4E on Ser209, and may contribute to tumorigenesis.
Catalog: PV5608
Size: 1 mg
Size: 1 mg
HIPK2 is a nuclear serine⁄threonine kinase that is linked to transcriptional regulation and apoptosis.
Catalog: PV5276
Size: 1 mg
Size: 1 mg
NUAK1 (ARK5) is a serine⁄threonine kinase that plays a role in many cellular functions. The overexpression of this kinase has been associated with tumor invasion and metastasis (colorectal neoplasm).
Catalog: PV4283
Size: 1 mg
Size: 1 mg
MAP3K2 (MEKK2) is a serine⁄threonine kinase that activates kinases involved in the MAP kinase signaling pathway.
Catalog: PV4010
Size: 1 mg
Size: 1 mg
MST4 is member of the Ste20-like kinase family of serine⁄threonine kinases and is overexpressed during prostate cancer development.
Catalog: PV4024
Size: 1 mg
Size: 1 mg
KDR (VEGFR2) is a type III receptor tyrosine kinase. It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors.
Catalog: PR5992A
Size: 1 mg
Size: 1 mg
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The T315I mutant is a Gleevec resistant form of ABL1.
Catalog: PV4184
Size: 1 mg
Size: 1 mg
BRAF acts upstream of MEK in the MAP kinase pathway and is involved in cell division, differentiation, and secretion. The BRAF mutant V599E is oncogenic and found in a variety of cancers.
Catalog: PV4173
Size: 1 mg
Size: 1 mg
TEC is a non-receptor protein-tyrosine kinase containing a pleckstrin homology domain and is highly expressed in many hematopoietic cell lines.
Catalog: PV4090
Size: 1 mg
Size: 1 mg
FGR is a SRC-related kinase present in hematopoietic cells. FGR signals within multiple pathways including within the integrin pathway and downstream of chemokine and cytokine receptors.
Catalog: PV4078
Size: 1 mg
Size: 1 mg
EPHA5 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system.
Catalog: PV4097
Size: 1 mg
Size: 1 mg
CAMK2B (CaMKII beta) is a serine⁄threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization and regulation of gene expression. As a dominant kinase in the central nervous system it may function in long term potentiation and neurotransmitter release.
Catalog: PV4278
Size: 1 mg
Size: 1 mg
YES1 is a recombinant human protein kinase that is a member of the SRC family of non-receptor tyrosine kinases and is the cellular homolog of the Yamaguchi sarcoma virus oncogene. It is involved in the regulation of cell growth and survival, including roles in apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. • Active —this protein can be used in kinase activity assays, such as Z’-LYTE® assays, or in a binding assay platform like the LanthaScreen® Eu Kinase Binding Assay (KBA). • Purified —purity is determined by gel electrophoresis and provided in lot-specific certi...
Catalog: A15559
Size: 1 mg
Size: 1 mg
NA Recombinant Influenza A Virus Protein subtype H1N1 (A/California/04 /2009) (NEURAMINIDASE), recombinant viral protein is supplied as a frozen protein. It is suitable for use in protein studies such as enzymetic analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the mature form of influenza A virus (A/California/04/2009 (H1N1)) neuraminidase (ACP41107.1) (His 36 -Lys 469) fused to a polyhistidine tag at...
Catalog: 11058-V07B-250
Size: 5 × 50 µg
Size: 5 × 50 µg
TaqMan® OpenArray® Genotyping Plate, Custom Format 192 QuantStudio™ 12K Flex
Catalog: 4471117
Size: 10 pack
Size: 10 pack
Perform up to 2,000 PCR reactions with Applied Biosystems® TaqMan® PCR Core Reagent kit, 10-Pack. Applied Biosystems® TaqMan® PCR Core Reagents, 10-pack provides the individual components needed to perform up to 2,000 PCR reactions (50 µl each). Features of the TaqMan® PCR Core Reagent Kit: • Separate components, packaged in 10 tubes, provide maximum flexibility in assay setup • AmpliTaq Gold® DNA polymerase, a chemically modified form of AmpliTaq® DNA Polymerase, improves specificity and yield • AmpErase® UNG protects against subsequent re-amplifications from PCR products containing dU to min...
Catalog: 402930
Size: 2000 reactions
Size: 2000 reactions
Products from Ret Recombinant Human Protein to Taqman® Pcr Core Reagent Kit (10-Pack)
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