Products from Abl1 Recombinant Human Protein to Irak1 Recombinant Human Protein
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response.
Catalog: PV3585
Size: 1 mg
Size: 1 mg
FER is a member of the FPS⁄FES family of non-receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
Catalog: PV4076
Size: 1 mg
Size: 1 mg
STK33 is a serine⁄threonine kinase involved in signal transduction and cellular communication.
Catalog: PV4354
Size: 1 mg
Size: 1 mg
The PKC family of serine⁄threonine kinases, including PRKCH (PKC eta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3608
Size: 1 mg
Size: 1 mg
CDC42BPA (MRCKA) is a serine⁄threonine kinase which functions in actin cytoskeleton assembly and organization.
Catalog: PV4434
Size: 1 mg
Size: 1 mg
ACVR2B is a type II member of the TGF-beta family of receptor ser⁄thr kinases and is involved in the activin and myostatin signaling pathway.
Catalog: PV6050
Size: 1 mg
Size: 1 mg
MYLK (MLCK) is a serine⁄threonine kinase that phosphorylates myosin regulatory light chains to assist in the production of contractile activity (myosin-actin interaction).
Catalog: PV4350
Size: 1 mg
Size: 1 mg
CSF1R (FMS) is involved in the production, differentiation, and function of macrophages, and is implicated in promyelocytic leukemias.
Catalog: PV4092
Size: 1 mg
Size: 1 mg
PAK7 (KIAA1264) is implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling.
Catalog: PV4441
Size: 1 mg
Size: 1 mg
PLK1 is a serine⁄threonine kinase that is thought to function in cell mitosis and regarded as a marker of cell proliferation. It has been found to play a critical role in carcinogenesis.
Catalog: PV4038
Size: 1 mg
Size: 1 mg
MYLK2 (skMLCK) is a calcium⁄calmodulin-dependent serine⁄threonine kinase expressed exclusively in adult skeletal muscle.
Catalog: PV4025
Size: 1 mg
Size: 1 mg
PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine⁄threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities.
Catalog: PV4566
Size: 1 mg
Size: 1 mg
STK16 (PKL12) is a serine⁄threonine kinase that functions in signal transduction pathways and transcriptional regulation.
Catalog: PV4442
Size: 1 mg
Size: 1 mg
ROR2 (receptor tyrosine kinase-like orphan receptor 2) is a type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. It is throught to be involved in the early formation of the chondrocytes and cartilage and growth plate development.
Catalog: PV4179
Size: 1 mg
Size: 1 mg
RPS6KA4 (MSK2) is a serine⁄threonine protein kinase that is essential for the regulation of various cellular processes. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos.
Catalog: PV4052
Size: 1 mg
Size: 1 mg
MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes.
Catalog: PV4903
Size: 1 mg
Size: 1 mg
CAMK2A (CaMKII alpha) is a serine⁄threonine kinase that regulates a number of cellular functions including neuronal processes, gene expression, carbohydrate metabolism, cytoskeletal function, and calcium homeostatsis. Autophosphorylation of threonine 286 in the presence of Ca2+ and calmodulin activates CAMK2A with the ability to switch from calmodulin-dependent to a calmodulin independent activity.
Catalog: PR4586A
Size: 1 mg
Size: 1 mg
The PKC family of serine⁄threonine kinases, including PRKCI (PKC iota), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
Catalog: PV3607
Size: 1 mg
Size: 1 mg
ROCK2, the predominant ROCK isoform in skeletal muscle, is an important regulator downstream of Rho GTPases.
Catalog: PV4048
Size: 1 mg
Size: 1 mg
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement.
Catalog: PV4119
Size: 1 mg
Size: 1 mg
AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome⁄spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction.
Catalog: PV4178
Size: 1 mg
Size: 1 mg
STK4 (MST1) is a serine⁄threonine kinase which may be involved in apoptosis. It is possible that this protein induces the chromatin condensation observed in this process.
Catalog: PV4177
Size: 1 mg
Size: 1 mg
DAPK3 is a serine⁄threonine kinase which is functionally linked to cell motility, smooth muscle contractility and cell death processes.
Catalog: PV3995
Size: 1 mg
Size: 1 mg
CSNK1G2 (CK1 gamma 2) is a serine⁄threonine kinase implicated in a wide range of cellular functions, including vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis.
Catalog: PV3990
Size: 1 mg
Size: 1 mg
The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylating eIF4E on Ser209, and may contribute to tumorigenesis.
Catalog: PV6024
Size: 1 mg
Size: 1 mg
EPHA3 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA3 encodes a protein that binds ephrin-A ligands.
Catalog: PV4095
Size: 1 mg
Size: 1 mg
PBK (TOPK) is a serine⁄threonine kinase that is related to the dual specific mitogen-activated protein kinase kinase (MAPKK). The kinase is up-regulated in a variety of hematological malignancies, participates in activating lymphoid cells, and supports testicular function (spermatogenesis).
Catalog: PV4285
Size: 1 mg
Size: 1 mg
ACVR1B is a serine⁄threonine kinase involved in signal transduction and cellular communication. Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors. Mutations of ACVR1B have been observed in pancreatic adenocarcinomas.
Catalog: PV4329
Size: 1 mg
Size: 1 mg
The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Catalog: PV4186
Size: 1 mg
Size: 1 mg
IL-1 receptor associated kinases (IRAKs) are serine⁄threonine kinases involved in signaling via Toll⁄IL-1 pathways.
Catalog: PV4439
Size: 1 mg
Size: 1 mg
Products from Abl1 Recombinant Human Protein to Irak1 Recombinant Human Protein
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