Category: Products & Services > Proteins, Enzymes, & Peptides > Growth Factors, Chemokines & Cytokines
Epidermal growth factor (EGF), recombinant canine protein is supplied as a lyophilized powder. It is suitable for use in performing cell based assays. In general, recombinant proteins can be used as protein standard and in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the mature form (Asn 973-Arg 1024) of canine EGF (Q9BEA0) fused to a polyhistidine tag at the N-terminus. Activity: Measured in a cell proliferation assay using BALB/c 3T3 mouse embryonic fibroblasts. The ED 50 for this effect is typically 0.1-0.5 ng/ml. Formulation: Lyoph...
Catalog: 70013-D07E-5
Size: 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Growth Factors, Chemokines & Cytokines
Epidermal growth factor (EGF), recombinant canine protein is supplied as a lyophilized powder. It is suitable for use in performing cell based assays. In general, recombinant proteins can be used as protein standard and in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the mature form (Asn 973-Arg 1024) of canine EGF (Q9BEA0) fused to a polyhistidine tag at the N-terminus. Activity: Measured in a cell proliferation assay using BALB/c 3T3 mouse embryonic fibroblasts. The ED 50 for this effect is typically 0.1-0.5 ng/ml. Formulation: Lyoph...
Catalog: 70013-D07E-50
Size: 50 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L858R mutation is implicated in epithelial tumor formation.
Catalog: PR7447A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L858R mutation is implicated in epithelial tumor formation.
Catalog: PV4289
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinase that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L861Q mutation is an Iressa-responsive mutant observed in the clinic.
Catalog: PR7435A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinase that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The EGFR L861Q mutation is an Iressa-responsive mutant observed in the clinic.
Catalog: PV4191
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The double T790M L858R mutant of EGFR displays resistance to Erlotinib (Tarceva) and sensitivity to HKI-272 and rapamycin combination therapy.
Catalog: PR8911A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The double T790M L858R mutant of EGFR displays resistance to Erlotinib (Tarceva) and sensitivity to HKI-272 and rapamycin combination therapy.
Catalog: PV4880
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The T790M mutant of EGFR has arisen in the clinics and displays resistance to Erlotinib (Tarceva) and Gefitinib (Iressa).
Catalog: PR8052A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The T790M mutant of EGFR has arisen in the clinics and displays resistance to Erlotinib (Tarceva) and Gefitinib (Iressa).
Catalog: PV4804
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics.
Catalog: PR7295B
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Receptor Tyrosine Kinases
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics.
Catalog: PV4190
Size: 1 mg
Category: Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > Protein Specific Primary Antibodies
This monoclonal antibody reacts with the extracellular domain of epidermal growth factor receptor (170 kDa). Clone 31G7 is useful in detecting the majority of squamous cell carcinomas that arise from both squamous epithelium and metaplastic squamous epithelium. Positive tissue: Breast carcinoma. Clone/PAD: 31G7 Immunogen: EGFr derived from A-431 cells Specificity: EGFr. No cross-reactivity observed with c-erbB-2. Reactivity: Human Applications: Immunohistochemistry (FFPE) Pretreatment: Epitope Retrieval: Not required , Enzyme Digestion: Required (Digest-All™ 3/Pepsin) Expected Staining Pattern...
Catalog: 28-0005
Size: 2 ml
Category: Products & Services > Proteins, Enzymes, & Peptides > Receptors & Cell Surface Markers > Growth Factor⁄Cytokine⁄Chemokine Receptors
Epidermal growth factor receptor (EGFR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in studying protein-protein interactions, and cell biology research applications. It can also be used as a protein standard. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gly 645) of human EGFR (NP_005219) fused to the Fc region of human IgG1 at the C-terminus...
Catalog: 10001-H02H-25
Size: 25 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Receptors & Cell Surface Markers > Growth Factor⁄Cytokine⁄Chemokine Receptors
Epidermal growth factor receptor (EGFR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in studying protein-protein interactions, and cell biology research applications. It can also be used as a protein standard. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gly 645) of human EGFR (NP_005219) fused to the Fc region of human IgG1 at the C-terminus...
Catalog: 10001-H02H-250
Size: 5 × 50 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Receptors & Cell Surface Markers > Growth Factor⁄Cytokine⁄Chemokine Receptors
Epidermal growth factor receptor (EGFR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in studying protein-protein interactions, and cell biology research applications. It can also be used as a protein standard. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gly 645) of human EGFR (NP_005219) fused to the Fc region of human IgG1 at the C-terminus...
Catalog: 10001-H02H-5
Size: 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Receptors & Cell Surface Markers > Growth Factor⁄Cytokine⁄Chemokine Receptors
Epidermal growth factor receptor (EGFR), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in studying protein-protein interactions, and cell biology research applications. It can also be used as a protein standard. Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gly 645) of human EGFR (NP_005219) fused to the Fc region of human IgG1 at the C-terminus...
Catalog: 10001-H02H-50
Size: 50 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
EIF2AK1 (HRI) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK1, signaling is initiated by low levels of heme.
Catalog: PR9072A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
EIF2AK1 (HRI) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK1, signaling is initiated by low levels of heme.
Catalog: PV5857
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
EIF2AK2 (PKR) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses. EIF2AK2 plays a key role in antiviral defense mediated through its direct activation by double-stranded RNA produced by viral infection.
Catalog: PR8917B
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
EIF2AK2 (PKR) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses. EIF2AK2 plays a key role in antiviral defense mediated through its direct activation by double-stranded RNA produced by viral infection.
Catalog: PV4822
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER.
Catalog: PV5106
Size: 10 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER.
Catalog: PR8985A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER.
Catalog: PV5107
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Eukaryotic Translation Initiation Factor 2C 1 (EIF2C1), recombinant human protein is supplied in frozen protein. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the full length of human EIF2C1 (NP_036331.1) (Met 1-Ala 857) fused to a polyhistidine tag at the N-terminus. Activity: This recombinant protein has not been tested. Formulation: 50 mM Tris, 100 mM NaCl, 10% glycerol, 0.5 PMSF, 0....
Catalog: 11225-H07B-25
Size: 5 × 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Eukaryotic Translation Initiation Factor 2C 1 (EIF2C1), recombinant human protein is supplied in frozen protein. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the full length of human EIF2C1 (NP_036331.1) (Met 1-Ala 857) fused to a polyhistidine tag at the N-terminus. Activity: This recombinant protein has not been tested. Formulation: 50 mM Tris, 100 mM NaCl, 10% glycerol, 0.5 PMSF, 0....
Catalog: 11225-H07B-5
Size: 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Eukaryotic Translation Initiation Factor 2C 1 (EIF2C1), recombinant human protein is supplied in frozen protein. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the full length of human EIF2C1 (NP_036331.1) (Met 1-Ala 857) fused to a polyhistidine tag at the N-terminus. Activity: This recombinant protein has not been tested. Formulation: 50 mM Tris, 100 mM NaCl, 10% glycerol, 0.5 PMSF, 0....
Catalog: 11225-H07B-250
Size: 5 × 50 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Eukaryotic Translation Initiation Factor 2C 1 (EIF2C1), recombinant human protein is supplied in frozen protein. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the full length of human EIF2C1 (NP_036331.1) (Met 1-Ala 857) fused to a polyhistidine tag at the N-terminus. Activity: This recombinant protein has not been tested. Formulation: 50 mM Tris, 100 mM NaCl, 10% glycerol, 0.5 PMSF, 0....
Catalog: 11225-H07B-50
Size: 50 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Eukaryotic Translation Initiation Factor 2C 2 (EIF2C2), recombinant mouse protein is supplied in frozen protein. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the mouse EIF2C1(Q8CJG0) (Met 1-Ala 860) fused to a polyhistidine tag at the N-terminus. Activity: This recombinant protein has not been tested. Formulation: 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.4. Reconstitution: No recons...
Catalog: 50683-M07B-25
Size: 5 × 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Eukaryotic Translation Initiation Factor 2C 2 (EIF2C2), recombinant mouse protein is supplied in frozen protein. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the mouse EIF2C1(Q8CJG0) (Met 1-Ala 860) fused to a polyhistidine tag at the N-terminus. Activity: This recombinant protein has not been tested. Formulation: 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.4. Reconstitution: No recons...
Catalog: 50683-M07B-5
Size: 5 µg