Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
PDK1 (3-phosphoinositide dependent kinase-1) is a serine⁄threonine protein kinase localized to the plasma membrane. It plays a vital role in insulin-induced glycogen synthesis, PKC activation, and activation of the AGC subfamily of protein kinases.
Catalog: PR4194C
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
PDK1 (3-phosphoinositide dependent kinase-1) is a serine⁄threonine protein kinase localized to the plasma membrane. It plays a vital role in insulin-induced glycogen synthesis, PKC activation, and activation of the AGC subfamily of protein kinases.
Catalog: PV4033
Size: 1 mg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
PDK4 (PDHK4), along with the other PDHKs, regulates glucose metabolism by phosphorylating the E1 alpha subunit of the mitochondrial pyruvate dehydrogenase complex. Inhhibition of PDHKs is viewed as a potential therapeutic treament for type II diabetes.
Catalog: PR8253A
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Kinases > Serine⁄Threonine Kinases
PDK4 (PDHK4), along with the other PDHKs, regulates glucose metabolism by phosphorylating the E1 alpha subunit of the mitochondrial pyruvate dehydrogenase complex. Inhhibition of PDHKs is viewed as a potential therapeutic treament for type II diabetes.
Catalog: PV5711
Size: 1 mg
Category: Products & Services > DNA Vectors, Clones, Purified Nucleic Acids & Libraries > DNA Vectors > Gateway® Donor Vectors - pDONR
Gateway® Technology enables rapid cloning of one or more genes into virtually any protein expression system. Once you have an entry clone, you can recombine your gene of interest into a variety of expression vectors adapted for use in Gateway® Technology. The PCR product is directionally cloned with efficiencies typically >99%. The pDONR™/Zeo vector haa a pUC origin for high plasmid yields and universal M13 sequencing sites for ease of use.
Catalog: 12535-035
Size: 6 µg
Category: Products & Services > DNA Vectors, Clones, Purified Nucleic Acids & Libraries > DNA Vectors > Gateway® Donor Vectors - pDONR
Gateway® Technology enables rapid cloning of one or more genes into virtually any protein expression system. Once you have an entry clone, you can recombine your gene of interest into a variety of expression vectors adapted for use in Gateway® Technology. The PCR product is directionally cloned with efficiencies typically >99%. The pDONR™221 vector haa a pUC origin for high plasmid yields and universal M13 sequencing sites for ease of use.
Catalog: 12536-017
Size: 6 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Podoplanin (PDPN), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Leu 141) of mouse PDPN (NP_034459.2) precursor fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. Activity: The activity of this protein has not been tested. Formulation: Lyophilized in PBS, p...
Catalog: 50256-M03H-25
Size: 5 × 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Podoplanin (PDPN), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Leu 141) of mouse PDPN (NP_034459.2) precursor fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. Activity: The activity of this protein has not been tested. Formulation: Lyophilized in PBS, p...
Catalog: 50256-M03H-5
Size: 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Podoplanin (PDPN), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain of human PDPN short isoform (Q86YL7-1) (Met 1-Lys 123) fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. Activity: Measured by its binding abili...
Catalog: 11065-H03H-25
Size: 5 × 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Podoplanin (PDPN), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain of human PDPN short isoform (Q86YL7-1) (Met 1-Lys 123) fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. Activity: Measured by its binding abili...
Catalog: 11065-H03H-250
Size: 5 × 50 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Podoplanin (PDPN), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain of human PDPN short isoform (Q86YL7-1) (Met 1-Lys 123) fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. Activity: Measured by its binding abili...
Catalog: 11065-H03H-5
Size: 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Podoplanin (PDPN), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the extracellular domain of human PDPN short isoform (Q86YL7-1) (Met 1-Lys 123) fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus. Activity: Measured by its binding abili...
Catalog: 11065-H03H-50
Size: 50 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Podoplanin (PDPN), recombinant mouse protein is supplied in frozen format. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the mouse PDPN N-terminal fragment (NP_034459.2) (Met 1-Lys 133) fused to a C-terminal polyhistidine tag. Activity: The activity of this protein has not been tested. Reconstitution: No reconstitution is needed. Store aliquots under sterile conditions at -80°C. Thaw pr...
Catalog: 50256-M08B1-25
Size: 5 × 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
Podoplanin (PDPN), recombinant mouse protein is supplied in frozen format. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the mouse PDPN N-terminal fragment (NP_034459.2) (Met 1-Lys 133) fused to a C-terminal polyhistidine tag. Activity: The activity of this protein has not been tested. Reconstitution: No reconstitution is needed. Store aliquots under sterile conditions at -80°C. Thaw pr...
Catalog: 50256-M08B1-5
Size: 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
PDZ Domain Containing 11 (PDZD11), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the human PDZD11 (NP_057568.1) (Asp 2-His 140) fused to a polyhistidinetag at the N-terminus. Activity: The activity of this protein has not been tested. Reconstitution: Dissolve the protein in sterile double distilled water to a concentration o...
Catalog: 12188-H07E-25
Size: 5 × 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Other Proteins & Peptides
PDZ Domain Containing 11 (PDZD11), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications. This recombinant protein was expressed from a DNA sequence encoding the human PDZD11 (NP_057568.1) (Asp 2-His 140) fused to a polyhistidinetag at the N-terminus. Activity: The activity of this protein has not been tested. Reconstitution: Dissolve the protein in sterile double distilled water to a concentration o...
Catalog: 12188-H07E-5
Size: 5 µg
Category: Products & Services > Antibodies & Secondary Detection Reagents > Primary Antibodies > Protein Specific Primary Antibodies
This is a purified rabbit anti-human PECAM-1 Polyclonal Antibody, that can be used in the validated applications of Western blot, ELISA, and immunohistochemistry. This PECAM-1 Polyclonal Antibody was produced in rabbits immunized with purified, recombinant human PECAM-1. PECAM-1 specific IgG was purified by human PECAM-1 affinity chromatograpy. Antibody characteristics include: Applications: This PECAM-1 Polyclonal Antibody, has been validated for use in Western blot, ELISA, and immunohistochemistry Host species and isotype: This is a rabbit Polyclonal IgG against human PECAM-1 Immunogen: Reco...
Catalog: 10148-RP02-AB
Size: 100 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Receptors & Cell Surface Markers > CD & Other Cell Surface Markers
Platelet/Endothelial Cell Adhesion Molecule 1 (PECAM1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Lys 601) of human PECAM1 (EAW94208.1) fused to the fused Fc region of human IgG1 at the C-terminus. Activity: Measured by its ability of the immobilized protein to support the adhesion of Jurkat h...
Catalog: 10148-H02H-25
Size: 5 × 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Receptors & Cell Surface Markers > CD & Other Cell Surface Markers
Platelet/Endothelial Cell Adhesion Molecule 1 (PECAM1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Lys 601) of human PECAM1 (EAW94208.1) fused to the fused Fc region of human IgG1 at the C-terminus. Activity: Measured by its ability of the immobilized protein to support the adhesion of Jurkat h...
Catalog: 10148-H02H-250
Size: 5 × 50 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Receptors & Cell Surface Markers > CD & Other Cell Surface Markers
Platelet/Endothelial Cell Adhesion Molecule 1 (PECAM1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Lys 601) of human PECAM1 (EAW94208.1) fused to the fused Fc region of human IgG1 at the C-terminus. Activity: Measured by its ability of the immobilized protein to support the adhesion of Jurkat h...
Catalog: 10148-H02H-5
Size: 5 µg
Category: Products & Services > Proteins, Enzymes, & Peptides > Receptors & Cell Surface Markers > CD & Other Cell Surface Markers
Platelet/Endothelial Cell Adhesion Molecule 1 (PECAM1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Lys 601) of human PECAM1 (EAW94208.1) fused to the fused Fc region of human IgG1 at the C-terminus. Activity: Measured by its ability of the immobilized protein to support the adhesion of Jurkat h...
Catalog: 10148-H02H-50
Size: 50 µg
Category: Products & Services > DNA Vectors, Clones, Purified Nucleic Acids & Libraries > DNA Vectors > Mammalian Expression Vectors
All pEF or pUB vectors contain a strong promoter for high-level expression in mammalian cells, a choice of selection marker for generating stable cell lines, and an epitope tag for easy detection with a monoclonal antibody and rapid purification on nickel-chelating resin. Each vector is available in three reading frames to simplify cloning in-frame with the fusion tag.
Catalog: V921-20
Size: 20 µg
Category: Products & Services > DNA Vectors, Clones, Purified Nucleic Acids & Libraries > DNA Vectors > Mammalian Expression Vectors
To fit all of your expression needs, Invitrogen offers state-of-the-art Gateway® destination vectors for expression in E. coli , insect, yeast, or mammalian cells, as well as for production of native protein or N- or C-terminal fusion proteins. All Gateway® destination vectors have att R sites for recombination with any att L-flanked fragment, regardless of whether it is an entry clone or an Ultimate™ RF Clone. The following table lists the wide range of destination vectors available. Additional materials required, available separately: Gateway® entry clone, Gateway® LR Clonase® enzyme mix, an...
Catalog: V6020-20
Size: 6 µg
Category: Products & Services > DNA Vectors, Clones, Purified Nucleic Acids & Libraries > DNA Vectors > Mammalian Expression Vectors
All pEF or pUB vectors contain a strong promoter for high-level expression in mammalian cells, a choice of selection marker for generating stable cell lines, and an epitope tag for easy detection with a monoclonal antibody and rapid purification on nickel-chelating resin. Each vector is available in three reading frames to simplify cloning in-frame with the fusion tag.
Catalog: V962-20
Size: 20 µg
Category: Products & Services > Instruments, Software, & Accessories > Imaging & Microscopy Accessories > Microscopy Accessories
A suite of accessories has been designed to enable research on living cells using your ArcturusXT™ LCM Instrument. Researchers may use slides or Petri dishes to perform imaging and microdissection experiments. Following a validated protocol from Arcturus® LCM Systems from Applied Biosystems—the leaders in tissue-based microdissection—the live cells may be isolated, remaining viable for subsequent re-culture or direct processing for use in downstream applications. Polyethylene naphthalate (PEN) Membrane Frame Slides for Live Cell Microdissection • Specially optimized for use with live cell expe...
Catalog: LCM0531
Size: 25 each
Category: Products & Services > Instruments, Software, & Accessories > Imaging & Microscopy Accessories > Microscopy Accessories
ARCTURUS® laser capture microdissection (LCM) instruments offer a unique combination of infrared (IR) laser capture and ultraviolet (UV) laser cutting, permitting the use of any slide type and any sample preparation for microdissection. While plain glass slides are effectively used for standard IR-based LCM, polyethylene naphthalate (PEN) membrane slides facilitate this Arcturus®-exclusive dual laser function and allow you to determine the appropriate sample preparation based on your application need. Plain Glass Slides The ARCTURUS® instruments are the only LCM systems that allow efficient us...
Catalog: LCM0522
Size: 50 each
Category: Products & Services > Cell Culture & Transfection Reagents > Antibiotics & Antimycotics
The combination of the antibiotics penicillin and streptomycin are used to prevent bacterial contamination of cell cultures due to their effective action against gram-positive and gram-negative bacteria, respectively. Penicillin was originally purified from the fungi Penicillium and acts by interfering directly with the turnover of the bacteria cell wall and indirectly by triggering the release of enzymes that further alter the cell wall. Streptomycin was originally purified from Streptomyces griseus . Streptomycin acts by binding to the 30S subunit of the bacterial ribosome leading to inhibit...
Catalog: 15070-063
Size: 100 ml
Category: Products & Services > DNA Vectors, Clones, Purified Nucleic Acids & Libraries > DNA Vectors > PCR Cloning Vectors
PENTR/D-TOPO CLONING KIT
Catalog: K240020SP
Size: 20 reactions
Category: Products & Services > DNA Vectors, Clones, Purified Nucleic Acids & Libraries > DNA Vectors > Gateway® Entry Vectors - pENTR
Gateway® entry vectors are designed to clone DNA sequences using restriction endonucleases and ligase to create a Gateway® entry clone. The entry clone is ready for recombination with a destination vector to create an expression clone. New: pENTR™ Dual Selection vectors! The Gateway® entry vectors (Table 1) offer the following: • attL1 and attL2 sites for site-specific recombination of the entry clone with a Gateway® destination vector to ensure cloning of the gene of interest in the correct orientation for expression • Kozak consensus sequence for efficient translation initiation in eukaryoti...
Catalog: A10462
Size: 10 µg
Category: Products & Services > DNA Vectors, Clones, Purified Nucleic Acids & Libraries > DNA Vectors > Gateway® Entry Vectors - pENTR
Gateway® entry vectors are designed to clone DNA sequences using restriction endonucleases and ligase to create a Gateway® entry clone. The resulting entry clone is ready for recombination with a destination vector to create an expression clone. New: pENTR™ Dual Selection vectors! The Gateway® entry vectors (Table 1) offer the following: • attL1 and attL2 sites for site-specific recombination of the entry clone with a Gateway® destination vector to ensure cloning of the gene of interest in the correct orientation for expression • Kozak consensus sequence for efficient translation initiation in...
Catalog: A10463
Size: 10 µg