This purified ABfinity™ recombinant rabbit anti-SAA1 monoclonal antibody is specific to mouse SAA1 protein. Serum amyloid A (SAA) proteins are involved in the acute phase responses; these are the immediate early host responses to inflammation. Rabbit anti-SAA1 monoclonal antibody is used in western blotting applications.

Antibody Specifications:

• Applications: The validated application for this rabbit anti-SAA1 monoclonal antibody is western blotting.
• Host Species and Isotype: The host species and isotype of the antibody is rabbit IgG.
• Clone ID of Monoclonal Antibody (mAb): The rabbit anti-SAA1 monoclonal antibody clone is D9H4L41
• Reactivity: Reacts with mouse Serum Amyloid A (SAA1).
• Product Size: Rabbit anti-SAA1 monoclonal antibody is available in a 100 µg size.

Serum Amyloid A (SAA) proteins comprise a family of small (12-14 kDa, 104-112 amino acid residues), differentially expressed proteins that are highly conserved among vertebrates. SAA proteins are involved in the acute phase responses; these are the immediate early host responses to inflammation. During the acute phase, circulating SAA levels are increased by 100-1000 fold, reaching concentrations of up to one milligram per milliliter. Liver is the major site of SAA synthesis, although extra-hepatic expression has also been reported. Mouse SAA gene family maps to chromosome 7. In mouse, five SAA genes and four protein products have been identified: mouse SAA1, SAA2, SAA3 are the acute phase isoforms, SAA5 is constitutively expressed, and SAA4 is a pseudogene. SAAs belong to a category of acute phase proteins that also includes C-reactive protein (CRP), haptoglobin, ceruloplasmin, complement components C3 and C4, a1-acid glycoprotein, a1-proteinase inhibitor, and fibrinogen.