Sodium pyruvate is commonly added to cell culture media as an energy source in addition to glucose. Since cells make sodium pyruvate as an intermediate metabolite in the glycolysis pathway, it is not a required supplement for all cell cultures. However, if cells have been grown in medium that is supplemented with sodium pyruvate, we recommend continuing use of the supplement as cell growth may lag without it. Gibco® Sodium Pyruvate (100 mM) is formulated using 11 g per liter of water. The final concentration of sodium pyruvate used in most cell culture media is 1 mM.

Dual-site cGMP Manufacturing and Quality System
Gibco® Sodium Pyruvate Solution is manufactured at a cGMP compliant facility, located in Grand Island, New York. The facility is registered with the FDA as a medical device manufacturer and is certified to ISO 13485 standards. For supply chain continuity, Life Technologies offers an identical Gibco® Sodium Pyruvate Solution product made in our Scotland facility (11360-039). This facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 standard.