This is a purified mouse anti-human JMJD6 monoclonal antibody (mAb) that can be used in the validated application of immunoprecipitation (IP).

Recombinant antibody characteristics include:

• APPLICATIONS: This JMJD6 mouse recombinant mAb has been validated for use in IP.
• HOST SPECIES AND ISOTYPE: This is a recombinant mouse monoclonal IgG1 antibody against human JMJD6.
• PRODUCT SIZE: 100 µg

Specific for JMJD6

JMJD6 (jumonji domain-containing protein 6) is a nuclear enzyme that acts as a bifunctional arginine demethylase and lysyl-hydroxylase, and it is encoded by the JMJD6 gene. As a dioxygenase, it belongs to a family of redox enzymes specifically involved in catalyzing oxidation reactions, and they are characterized by the presence of a highly conserved jumonji C (Jmjc)-domain. As an arginine demethylase, JMJD6 plays a critical role in the histone code by demethylating histone H3 and histone H4. As a lysyl-hydroxylase, JMJD6 catalyzes target protein lysine.

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