|CD45R (B220), Rat IgG2a monoclonal|
|Qdot® 800 nanocrystal|
Ex/ Em and laser configuration:
|405 (488 or 647)/ 800 nm, violet, violet or red laser|
Leukocyte Workshop Status:
Specificity for CD45R (B220)
The RA3-6B2 monoclonal antibody (mAb) reacts with an exon A-specific epitope on CD45, which is expressed essentially on all B cells and is maintained throughout B cell development. Although RA3-6B2 epitope is expressed in a restricted manner by B cells, it is also present on lymphokine activated killer (LAK) cells. Although B220 has been widely used as a pan B cell marker, CD19 may be a more appropriate pan B cell marker, since expression of CD19 appears to be more closely restricted to B cells. The RA3-6B2 mAb has been shown to potentiate isotype switching in B cells and to inhibit proliferative responses of B cell mitogens on B cells. Applications of RA3-6B2 include immunostaining for flow cytometry and immunoprecipitation.
Use the primary antibody selector tool to see the full list of CD45R (B220) antibodies.
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