This purified recombinant human biotinylated Fab recognizes DOT1L in human samples.

Recombinant antibody characteristics include:

• Validation in immunoprecipitation (IP)
• Superior lot-to-lot consistency
• Extremely high specificity and sensitivity
• Recombinant human biotinylated Fab
• Specific for DOT1L /b>

DOT1L is a histone methyltransferase. It methylates lysine-79 of histone H3. DOT1L binds DNA and compared to free histones, nucleosomes are preferred substrate for DOT1L.

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