Gibco® SensiCell™ RPMI (Roswell Park Memorial Institute) 1640 Medium is an enriched basal medium that enhances growth of sensitive or difficult-to-culture mammalian cells with standard Fetal Bovine Serum (FBS) supplementation. Compared to classic RPMI, SensiCell™ RPMI is formulated with GlutaMAX™ and additional nutrients that can increase cell viability and viable cell density. SensiCell™ RPMI requires supplementation, commonly with 10% Fetal Bovine Serum. Many cell lines do not require adaptation to this media.

SensiCell™ RPMI uses a sodium bicarbonate buffer system (2 g/L) and therefore requires a 5–10% CO2 environment to maintain physiological pH. Cells successfully cultured in SensiCell™ RPMI, with little or no adaptation, include ST-486, HL-60, and NK-92.

cGMP Manufacturing and Quality System
Gibco® SensiCell™ RPMI 1640 is manufactured at a cGMP compliant facility located in Grand Island, New York. The facility is registered with the FDA as a medical device manufacturer and is certified to the ISO 13485 and ISO 9001 standards.